Organ affected |
lSSc (n = 124) |
dSSc (n = 114) |
Fisher's exact p value |
Raynaud's phenomenon | 123 (99) | 113 (99) | NS |
Lung† | 32 (32) | 58 (56) | 0.0011 |
Kidney | 3 (2) | 7 (6) | NS |
Oesophagus | 50 (40) | 62 (54) | 0.027 |
Heart | 9 (7) | 24 (21) | 0.0025 |
Digital pitting scars/ulcers/gangrene | 63 (51) | 77 (68) | 0.012 |
Joints | 32 (26) | 34 (30) | NS |
Peripheral neuropathy | 2 (2) | 3 (3) | NS |
Pulmonary evaluation | (n = 99) | (n = 104) | |
Interstitial fibrosis | 28 (28) | 57 (55) | 0.0003 |
Isolated pulmonary hypertension | 4 (4) | 1 (1) | NS |
Isolated reduction of Tlco 2-150 | 7 (7) | 12 (12) | NS |
↵2-150 Tlco = carbon monoxide transfer factor. †For patients with pulmonary evaluation n = 99 for lSSc and 104 for dSSc.