Table 1

Anti-TNF α treatments

Name Description
D2E7Fully human anti-TNF α mAb
CDP571Humanised anti-TNF α mAb (murine CDR)
EtanerceptFusion protein consisting of two recombinant p75 TNF α  receptors and the Fc portion of human IgG1
Infliximab (cA2)Chimeric murine/human anti-TNF-α mAb
  • TNF=tumour necrosis factor; mAb=monoclonal antibody; IgG=immunoglobulin G; CDR=complementarity determining region.