Table 3

Indices of responsiveness at week 28 of follow up, for each treatment group^3-150

		Combined treatment (n=75)			Sulfasalazine (n=79)		t Value
		Mean change	SE_Δ		*SRM*	ES	t Value		Mean change	SE_Δ	SRM	ES
Count core set measures ⩾20% improved	5.8	0.2	3.6	—	4.5	0.3	1.9	—	3.9
Change in disease activity by patient, 7 point Likert	2.5	0.1	2.8	—	1.6	0.2	1.1	—	4.6
Pooled index composite measure	1.5	0.1	2.4	—	0.8	0.1	1.1	—	5.7
MACTAR interview	12	0.6	2.3	3.3	8.6	0.8	1.2	2.2	3.8
Count core set measures ⩾50% improved	4.8	0.3	2.2	—	3.0	0.3	1.2	—	4.7
Disease activity score (DAS) composite measure	−2.3	0.1	1.8	2.2	−1.4	0.1	1.0	1.4	4.4
AIMS pain scale	−8.5	0.5	1.8	2.4	−5.8	0.6	1.2	1.4	3.5
Health Assessment Questionnaire	−1.1	0.1	1.4	1.5	−0.6	0.1	0.9	0.8	4.5
Pain assessment by patient, VAS	−3.4	0.3	1.4	1.7	−2.0	0.3	0.7	0.9	3.2
Disease activity by patient, 5 point Likert	−1.8	0.2	1.4	1.7	−1.2	0.1	1.0	1.2	2.8
ESR (mm/1st h)	−40	3	1.4	1.2	−27	3	1.0	0.8	3.1
Swollen joint count ARA 48	−10	1	1.3	1.1	−5	1	0.7	0.7	3.4
Grip strength (kPa)	25	2	1.5	1.6	11	2	0.7	0.5	5.6
Count core set measures ⩾70% improved	3.6	0.3	1.5	—	1.9	0.2	0.9	—	4.4
Global assessment by observer, VAS	−3.3	0.3	1.3	1.4	−1.7	0.3	0.7	0.8	3.9
Physical function by patient, 6 point Likert	2.0	0.2	1.3	1.7	1.4	0.2	0.7	1.2	2.5
Utility^3-151 rating scale technique	0.24	0.02	1.3	1.3	0.15	0.02	0.8	0.8	2.7
Tender joint count ARA 68	−16	2	1.1	1.2	−8	2	0.5	0.5	3.7
Ritchie Arthritis Index tender joints	−11	1	1.2	1.1	−7	1	0.8	0.7	2.4
CRP (mg/l)	−32	5	0.9	0.8	−22	4	0.7	0.7	1.5
AIMS mobility scale	5.3	0.6	1.0	1.0	3.2	0.6	0.6	0.5	2.6
Global assessment by patient, VAS	−2.4	0.3	1.0	1.2	−1.9	0.3	0.7	1.0	1.1
AIMS self efficacy scale	5.2	0.7	0.8	0.9	2.9	0.7	0.4	0.4	2.3
Utility^3-151 standard gamble technique	0.10	0.02	0.7	0.7	0.06	0.02	0.3	0.3	1.4

↵3-150 Abbreviations, see table 2. SRM 95% confidence intervals have a width of <0.5 around the listed value, between-SRMs differences ⩾0.35 are significant (two sided p<0.05, no correction for multiple comparison).
↵3-151 Utilities were only assessed at week 28.