Production of superoxide anion radicals measured by chemiluminescence
| Production rate (counts/10 s/105phagocytes) | CMLI2-150(counts/10 s/105 phagocytes) | ||||||
|---|---|---|---|---|---|---|---|
| Healthy subjects | Patients with AS | Healthy subjects | Patients with AS | ||||
| Resting | 6.2 (1.5) (0–26.1) | 60.9 (18.6) (0–354.7)2-151 | ND | ND | |||
| (n = 21, age 22–47) | (n = 24, age 19–54) | ||||||
| fMLP2-150 | 34.9 (5.9) (4.9–62.8) | 178.8 (36.9) (9.2–498.2)2-151 | 59.8 (11.3) (17.5–131.9) | 237.2 (45.0 (17.2–584.2)2-151 | |||
| (n = 9, age 23–42) | (n = 18, age 19–54) | ||||||
| PMA2-150 | 105.2 (19.1) (33.6–194.4) | 583.0 (112.8) (87.2–2006.3)2-151 | 150.2 (25.6) (56.5–282.5) | 766.5 (127.1 (139.2–2166.5)2-151 | |||
| (n = 9, age 23–42) | (n = 20, age 19–54) | ||||||
↵2-150 CMLI = chemiluminescence maximal light intensity; fMLP =N-formyl-methionyl-leucyl-phenylalanine; PMA = phorbol-12-myristate-13-acetate; n = number of patients; ND = not done.
All results are expressed as mean (standard error) (range).
↵2-151 p<0.01 compared with healthy subjects by Mann-Whitney U test.