Table 1

Expression of hMLH1 and hMSH2 in different tissue specimens. The semiquantitative analysis shows the number of cells positive for hMLH1 or hMSH2

hMLH1 hMSH2
Rheumatoid arthritis, lining layer++++
Rheumatoid arthritis, sublining++++
Osteoarthritis, lining+(+)
Osteoarthritis, sublining(+)(+)
Normal colon+—+++—++
Colon carcinomaNegative—(+)Negative—(+)

  • ++ = >50 %; +–++ = 30–50 %; + = 10–30 %, (+) = <10 %.