Comparison of throat culture negative cases of post-streptococcal reactive arthritis (GUS) without and with previous antibiotic treatment (n=28). Data are means (SEM)
| Without antibiotic pre-treatment (n=10) | With antibiotic pre-treatment (n=18) | Significance | |
|---|---|---|---|
| 36 SJI | 4.5 (1.7) | 6.3 (1.3) | NS |
| 28 SJI | 3.7 (1.6) | 4.7 (1.0) | NS |
| Extra-articular manifestations (%) | 60 | 44 | NS |
| ESR (normal <10 mm 1st h) | 66 (10) | 62(8) | NS |
| CRP (normal <9 mg/l) | 84 (20) | 58(13) | NS |
| Leucocyte count (×109/l) | 11.3 (2.0) | 9.4 (0.9) | NS |
| ASO max (U/l) | 1335 (445) | 1480 (450) | NS |
| anti-DNase-B max (U/l) | 1080 (280) | 950 (125) | NS |
| ASO: anti-DNase-B ratio | 1.07 (0.32) | 1.64 (0.40) | NS |
| Recovery (days) | 18 (5) | 46 (9) | NS |
Extra-articular manifestations are erythema nodosum, erythema multiforme, hepatitis or lobular panniculatis.