Ecstasy toxicity and rheumatological differential diagnosis
| Ecstasy adverse effect | Rheumatological differential diagnosis |
|---|---|
| Seizures, psychiatric effects, organic cerebral damage3,4,9,10 | Cerebral lupus Cerebral vasculitis Drug adverse effects |
| Muscle pain,increased CK, rhabdomyolysis | Myositis |
| Abnormal liver function tests, hepatitis | Drug adverse effects, for example, SASP, MTX Hepatitis in association with autoimmune disease |
| Aplastic anaemia11 | Related to autoimmune disease Related to DMARDs |
| Pyrexia | Disease activity (systemic onset JCA, SLE, etc) Infection DMARD associated drug fever |
| Renal failure | Nephritis in association with CT disease/vasculitis Progression of amyloid Drug adverse effects Scleroderma renal crisis |
Disease modifying antirheumatic drug (DMARD), sulphasalazine (SASP), methotrexate (MTX), systemic lupus erythematosis (SLE), connective tissue (CT).