Table 1

Blood count and serological findings

Variable Value
White blood cells (/l)16.6 ×109
 Stab (%)7.0
 Segmented (%)75.5
 Lymphocytes (%)7.5
 Monocytes (%)6.5
 Eosinophils (%)3.0
 Basophils (%)0.5
Haemoglobin (g/l)8.8
Platelets (×1010/l)49.2
Erythrocyte sedimentation rate (mm/1st h)134
Angiotensin converting enzyme (IU/l)8.31-150
Adenosine deaminase (IU/l)8.01-150
C reactive protein (mg/l)148
IgG (g/l)13.45
IgA (g/l)6.45
IgM (g/l)4.27
C3 (g/l)1.2
C4 (g/l)0.1
CH50 (arb unit)41.5
Antinuclear antibody (titre)<20×
Rheumatoid factor (IU/ml)1-151 2390
P-ANCA1-152 (EU)65
C-ANCA1-154(EU)<10
STS1-160 (−)
2,5AS activity1-164 (pmol/l)<2001-150
Anti-hepatitis C virus(−)
Anti-HTLV-11-161 (−)
Anti-cytomegalovirus(−)
Anti-Epstein-Barr virus (IgG)(−)
Tumour markers
 CEA (μg/l)2.21-150
 CA-125 (U/ml)131-150
 Ferritin (μg/l)274

  • ↵1-150 These values are within the normal limit.

  • ↵1-151 Detected by a kit (RF, Eiken Ltd, Tokyo, Japan) using a latex agglutination method. Cut off value is <10 IU/ml.

  • ↵1-152 P-ANCA = perinuclear antineutrophil cytoplasmic antibody; detected by an enzyme linked immunosorbent assay kit (MPO-ANC, Nipro Ltd, Osaka, Japan) using myeloperoxidase. Cut off value is <10 EU. The sensitivity and specificity for the crescent forming nephritis and/or focal necrotising nephritis are 76.4 and 87.4%, respectively. Possibility of the interference by various factors, including rheumatoid factor (<500 IU/ml), chylomicron, glutathione (<500 mg/l), anti-dsDNA antibodies, and C-ANCA, has been excluded. 10 to 20 EU is a grey zone in RA.

  • ↵1-154 C-ANCA detected by an enzyme linked immunosorbent assay kit (PR3-ANC, Nipro Ltd) using protein . Cut off value is <10 EU.

  • ↵1-160 Serological test for syphilis .

  • ↵1-164 2',5'-Oligoadenylate synthetase activity, which rises in non-specific viral infections.

  • ↵1-161 Human T cell leukaemia virus 1.