Table 2

p Values derived from analysis of synovial fluid data using split plot model for group, time, and group by time interaction, and backward elimination to determine significance of covariates (body mass index, sex, age, and Kellgren-Lawrence grade)

	Log 3B3	Log 7D4	Log GAG^2-151	3B3/GAG	7D4/GAG
Group (control or exercise)	0.049^2-150	0.829	0.009^2-150	0.404	0.320
Time	0.409	0.161	0.841	0.549	0.192
Group × time interaction	0.203	0.789	0.057	0.118	0.302
Body mass index	x	x	x	x	x
Sex	x	x	x	x	x
Age	0.001^2-150	x	0.007^2-150	0.049^2-150	x
Kellgren-Lawrence grade	x	x	x	x	x

↵2-150 Significant effect (p<0.05).
↵2-151 GAG = glycosaminoglycan.
x corresponds to covariates that were removed as a result of backward elimination.