GST genotypes and measures of disease outcome and activity in 122 RA patients with disease duration 5–10 years
| Genotype | Number | Larsen score (SD) | HAQ (SD) | MAUCESR (SD) | MAUCCRP (SD) |
|---|---|---|---|---|---|
| GSTM1 null | 63 | 89.9 (43.3) | 1.33 (0.82) | 27.9 (18.0) | 17.1 (14.6) |
| GSTM12-150A | 42 | 70.7 (42.8) | 1.22 (0.86) | 24.3 (13.7) | 15.1 (16.9) |
| GSTM12-150B | 15 | 83.2 (32.3) | 1.67 (0.91) | 30.4 (10.7) | 20.8 (17.8) |
| GSTM12-150A/2-150B | 1 | 115.0 | 1.80 | 46.9 | ND |
| GSTM1 non-null | 58 | 74.7 (40.4)2-150 | 1.39 (0.89) | 26.3 (13.3) | 16.8 (17.1) |
| GSTM32-150A/2-150A | 86 | 86.3 (43.3) | 1.34 (0.86) | 27.9 (17.3) | 17.8 (17.1) |
| GSTM32-150A/2-150B | 23 | 77.3 (40.9) | 1.18 (1.18) | 25.0 (12.4) | 15.8 (14.8) |
| GSTM32-150B/2-150B | 3 | 98.3 (30.9) | 1.33 (1.18) | 23.2 (13.8) | 21.8 (20.1) |
| GSTM3 non2-150A/2-150A | 26 | 79.7 (40.0) | 1.19 (0.86) | 24.8 (12.3) | 16.4 (14.1) |
| GSTT1 null | 28 | 77.9 (33.4) | 1.54 (0.87) | 30.8 (18.8) | 20.3 (21.3) |
| GSTT12-150A/2-150A | 93 | 84.0 (44.9) | 1.28 (0.84) | 26.0 (14.8) | 15.9 (13.7) |
| GSTP12-150A/2-150A | 41 | 82.3 (39.37) | 1.45 (0.92) | 23.7 (15.5) | 15.8 (14.4) |
| GSTP12-150A/2-150B | 44 | 82.7 (46.0) | 1.21 (0.86) | 30.0 (17.6) | 18.1 (18.7) |
| GSTP12-150B/2-150B | 10 | 107.1 (35.4) | 1.52 (0.70) | 32.0 (16.8) | 21.4 (18.4) |
| GSTP1 non2-150B/2-150B | 85 | 82.5 (42.5) | 1.27 (0.87) | 27.2 (16.6) | 16.9 (16.7) |
↵2-150 p=0.039 (compared with GSTM1 null, after correction for age, sex, and disease duration). ND = not done.