Table 2

Differential diagnosis of chronic wrist pain with most discriminating features in the history, examination and imaging for each diagnosis

DiagnosisHistoryExaminationImaging
Intra-capsular
Fracturetraumatic eventpoint tendernessSR, SV (carpal tunnel) or CT
Ligament tearclicking, (unnoticed) traumatic eventpoint tenderness
ST: Watson’s test (scaphoid),
SR: malalignement (lateral “zigzag”) or dissociation carpal bones
McMurray’s test (TFCC)AG: leakage between different compartments of wrist
DRUJ subluxationpainful pronation and supinationprominent ulnar headSR: lateral view unreliable
ST: DRUJ compression during pro- and supinationCT: axial view
Arthritisspontaneous swelling, symptomatology other joints or systemic complaintsswelling, warmth, erythema, decreased painful range of movementSV: decreased mineralisation, cortical interruption or crystal deposits
US: hydrops or synovial proliferation
US punction/biopsy
Osteoarthritis(gradually) progressive pain and stiffnessdecreased passive range of movement, crepitusSR: with PA oblique (CMC-I, STT) or AP oblique (pisotriquetral)
ST: (pisiform) Grind test
NeoplasmNDNDSR
(osteoid osteoma)(pain at night, relief of salicylates)CT/MRI: determining extent lesion and effect on surrounding neurovascular structures
(SR/CT: nidus with radiolucent or sclerotic centre)
Ganglialocalised painful swellingtense discrete subcutaneous swellingUS: anechoic cyst area
MRI: occult or intraosseus
Avascular necrosispain without swellingdecreased painful range of movementSR: subtly increased radiodensity
BS: increased uptake
MRI: abnormal
OtherNDNDSR
(carpal boss)(swelling base 2nd or 3th metacarpal)(tender bony prominence)(SV: carpal boss view)
Extra-capsular
Neuropathyparesthesia, nocturnal excacerbation of symptoms, metabolic diseaseatrophySR: PA view
ST: Tinel and Phalen tests, diagnostic lidocaine injection (neuroma)SV: carpal tunnel view
EMG: abnormal nerve conduction time
US: swelling/flattening median nerve and increased palmar bowing retinaculum
Tendinopathyburning pain, highly repetitious and forceful motionsswelling, crepitus, snapping,SR: calcifications
ST: isometric function tests, forced stretching (Finkelstein’s test)US: thickened tendon with peritendinous effusions
  • (ST: stress test, ND: non-discriminating, SR: standard radiograph, SV: supplemental view, EMG: electromyelogram, AG: arthrography, US; ultrasonography, BS: bone scan, MRI: magnetic resonance imaging).