Clinical manifestations during the evolution of SLE in the childhood onset patients compared with the adult onset patients
| Manifestations | Childhood onset (n=34) | Adult onset (n=396) | p Value | ||||
|---|---|---|---|---|---|---|---|
| no (%) | no (%) | ||||||
| Malar rash | 27 (79) | 203 (51) | 0.002 | ||||
| Discoid lesions | 5 (15) | 17 (4) | NS | ||||
| Subacute cutaneous lesions | 1 (3) | 25 (6) | NS | ||||
| Photosensitivity | 15 (44) | 140 (35) | NS | ||||
| Oral ulcers | 13 (38) | 100 (25) | NS | ||||
| Arthritis | 30 (88) | 320 (81) | NS | ||||
| Serositis | 11 (32) | 109 (27) | NS | ||||
| Nephropathy | 17 (50) | 136 (34) | NS | ||||
| Neurological involvement | 9 (26) | 63 (16) | NS | ||||
| Thrombocytopenia | 9 (26) | 91 (23) | NS | ||||
| Haemolytic anaemia | 5 (15) | 26 (6) | NS | ||||
| Fever | 21 (62) | 170 (43) | NS | ||||
| Raynaud’s phenomenon | 7 (20) | 100 (25) | NS | ||||
| Livedo reticularis | 2 (6) | 5 (1) | NS | ||||
| Thrombosis | 0 (0) | 31 (8) | NS | ||||
| Myositis | 1 (3) | 28 (7) | NS | ||||
| Lung involvement | 2 (6) | 15 (4) | NS | ||||
| Chorea | 3 (9) | 0 (0) | <0.001 | ||||
| Sicca syndrome | 3 (9) | 61 (15) | NS | ||||
| Lymphadenopathy | 2 (6) | 3 (1) | NS | ||||