Effect of hydroxychloroquine treatment on various laboratory parameters
| Time (0) | Time (6 months) | Time (12 months) | |
|---|---|---|---|
| ESR (mm 1st h) | 43.1 (18.6) | 37.2 (15.1) | 27.2 (12.4)* |
| CRP (mg/dl) | 3.4 (1.1) | 3.1 (1.2) | 2.1 (0.7)* |
| IgG (mg/dl) | 2350 (460) | 2190 (450) | 1560 (310)* |
| IgM (mg/dl) | 320 (45) | 305 (41) | 295 (50) |
| IgA (mg/dl) | 300 (25) | 295 (30) | 280 (35) |
| Salivary flow rate ml/min | 0.07 (0.01) | ND | 0.08 (0.02) |
| Serum IL6 (pg/ml) | 5.4 (0.6) | 4.5 (0.8) | 2.9 (0.2)† |
| Salivary IL6 | 13.2 (1.2) | 8.7 (1.6)* | 7.3 (1.1)* |
| Serum HA (μg/l) | 142.4 (90.7) | 130.8 (97) | 106 (69) |
| Salivary HA | 577.8 (120) | 381.6 (115.2) | 200.2 (34)† |
| Serum sIL-2R (pg/ml) | 1481.4 (163.5) | 1471 (146) | 1463.6 (125.9) |
| Salivary sIL-2R | 74.3 (6.8) | 68.1 (5.8) | 65.2 (4.7) |
ND = Not done. *p<0.05. †p<0.001. Data are presented as mean (SEM).