HLA DRB11-150 frequencies in RS3PE patients. Comparative study with seronegative RA and controls
| RS3PE patients | HLA DRB11-150 | DR1/DR4 variants | |
|---|---|---|---|
| 1 | 11,07 | ||
| 2 | 03,04 | DRB11-1500401 | |
| 3 | 16,04 | DRB11-1500404 | |
| 4 | 13,15 | ||
| 5 | 07,15 | ||
| 6 | 13,15 | ||
| 7 | 03,(−) | ||
| 8 | 13,14 | ||
| 9 | 04,10 | DRB11-1500405, | 1001 |
| 10 | 04,08 | DRB11-1500404 | |
| 11 | 11,(−) | ||
| 12 | 01,11 | DRB11-1500101 | |
| HLA DRB11-150 | RS3PE (n=12) | Seronegative RA (n=15) | Healthy controls (n=104) |
| 1 or 2 SE | 5 (41.6%)1-150 | 8 (53.3%)† | 37 (35.5%) |
| X/X | 7 (58.8%) | 7 (46.6%) | 67 (64.4%) |
| 1-1500101 | 1 | 3 | 14 |
| 1-1500102 | 0 | 1 | 0 |
| 1-1500401 | 1 | 1 | 8 |
| 1-1500404 | 2 | 1 | 3 |
| 1-1500405 | 1 | 1 | 3 |
| 1-1501001 | 1 | 2 | 4 |
↵1-150 χ2 test between RS3PE and controls (p=0.08).†χ2 test between seronegative RA and controls (p=0.29). RA, rheumatoid arthritis. SE, subtypes encompassing the shared epitope. X, all alleles except DRB1 1-1500101, 1-1500401, 1-1500404, 1-1500405, 1-1500408, 1-1501001.