Degree of clinical improvement stratified by shared epitope status
| Treatment group | Shared epitope status | Change in tender joints | Change in swollen joints | ||
|---|---|---|---|---|---|
| Methotrexate | Negative | −19.5 (1.4) | −19.2 (10.1) | ||
| }p=0.95 | }p=0.97 | ||||
| All three drugs | Negative | −20.0 (21.0) | −19.4 (15.1) | ||
| Methotrexate | Positive | −12.5 (14.7) | −15.0 (15.4) | ||
| }p=0.007 | }p=0.019 | ||||
| All three drugs | Positive | −23.4 (9.1) | −25.9 (11.1) | ||
Values are mean (SD) of the change in scores from start of treatment until study completion.