Table 2

Activation markers on monocytes

MarkerCellular distributionRemarksMonoclonal antibodySource
MPOneutrophilsincreased expression after priming4.15CLB
monocytes
Pr3neutrophilsincreased expression after priming12.8CLB
monocytes
HLEneutrophilsincreased expression after primingNP57Dako
monocytes
CD63monocytesGP53, increased expression after primingCLB-gran/12,435CLB
granulocytes
activated platelets
CD11bmonocytesincreased expression after priming, subunit of beta2 integrin CD18/ CD11b (Mac-1), ligand for ICAM-1, β glucan, fibrinogen, C3bi.2LPM19cDako
macrophages
granulocytes
NK cells
CD49dmonocytesadhesion molecule, subunit of beta1 integrin CD29/CD49d (VLA-4).HP2/1Imm. tech
lymphocytes
eosinophils
FcγRI (CD64)monocytesincreased expression after activation, constitutively expressed on monocytes,22Medarex
granulocytes
  • CLB; Central Laboratory for the Bloodtransfusion Service, Amsterdam, the Netherlands, Dako; Dakopatts, Glostrup, Denmark, Imm. tech, Immunotech, Marseilles, France; Medarex, Annandale, USA.