Relation between methylenetetrahydrofolate reductase (MTHFR) genotype and plasma homocysteine, mean/median (P25, P75)
| MTHFR4-150 | n | Hcys†week 0 | n | Hcys† week 52 | p value‡ |
|---|---|---|---|---|---|
| 0 | 40 | 13.6/13.9 (11.8, 15.7) | 31 | 15.1/14.2 (12.9, 19.1) | <0.05 |
| 1 | 53 | 14.6/14.6 (12.2, 17.0) | 44 | 18.4/18.3 (14.5, 23.0) | <0.05 |
| 2 | 10 | 19.6/17.7 (14.4, 24.5) | 9 | 19.4/21.0 (17.7, 23.3) | >0.05 |
| p value§ | <0.05, 2v 1 and 0 | <0.05, 2 and 1v 0 |
↵4-150 0: no mutation, 1: heterozygous, 2: homozygous for the C677T mutation. †Homocysteine. ‡intra-group comparison: baselinev week 52. §inter-group comparison.