Variable | Change from baseline to week 52 | ||
---|---|---|---|
SSZ | MTX | COMBI | |
DAS | −1.8 (−2.3,−1.3) | −2.0 (−2.4,−1.7) | −2.3 (−2.7,−1.9) |
Number of swollen joints | −9.2 (−12.2,−6.3) | −12.4 (−15.4,−9.5) | −14.3 (−17.3,−11.4) |
Ritchie articular index | −9.2 (−11.7,−6.8) | −9.5 (−11.6,−7.5) | −10.6 (−12.5,−8.7) |
Number of painful joints | −12.5 (−15.9,−9.1) | −15.2 (−18.2,−12.2) | −16.9 (−20.4,−13.5) |
VAS general health (mm) | −15.4 (−25.8,−5.0) | −21.3 (−30.2,−12.3) | −20.6 (−27.6,−13.7) |
ESR (mm/h) | −17 (−26,−8) | −21 (−28,−15) | −28 (−37,−19) |
MTX: methotrexate, COMBI: combination of methotrexate and sulphasalazine, SSZ: sulphasalazine, DAS: Disease Activity Score, VAS: Visual Analogue Scale (0–100 mm).