Frequency of VDR positive cells in rheumatoid tissues
| VDR+specimens/total | Assessment of positive staining | ||||
|---|---|---|---|---|---|
| ++++ | +++ | ++ | + | − | |
| 1 Rheumatoid synovium*(n=10) | |||||
| 10/10 | 1 | 4 | 3 | 2 | 0 |
| 2 “Rheumatoid” cartilage (n=10) | |||||
| 5/10 | 0 | 0 | 0 | 5 | 5 |
| 3 CPJs (n=18) | |||||
| chondrocytes 10/18 | 0 | 0 | 3 | 7 | 8 |
| pannus 12/18 | 0 | 0 | 3 | 9 | 6 |
| interface 8/18 | 0 | 0 | 2 | 6 | 10 |
| 4 Normal cartilage (n=10) | |||||
| 1/10 | 0 | 0 | 0 | 1 | 9 |
+, ++, +++, and ++++ represent gradings of <5, 5–10, 10–20 and up to 60% of total cells, respectively, as determined by two independent assessors; −, no cells stained for VDR. *Synovial tissue remote from cartilage interface.