Sensitivity, specificity, and positive predictive value for severe destructive RA of five autoantibodies, inflammatory parameters (ESR, CRP), and high risk HLA alleles in two groups of RA patients
| Variable | Sensitivity | Specificity | Positive predictive value | OR | 95% CI |
|---|---|---|---|---|---|
| RF | 0.69 | 0.51 | 0.58 | 2.41 | 0.99, 5.85 |
| APF | 0.46 | 0.74 | 0.64 | 2.52 | 1.01, 6.28 |
| AKA | 0.60 | 0.72 | 0.68 | 3.95 | 1.59, 9.75 |
| RA 33 | 0.34 | 0.72 | 0.55 | 1.38 | 0.55, 3.45 |
| ANA | 0.20 | 0.72 | 0.42 | 0.68 | 0.25, 1.84 |
| HLA DRB1*04 or DRB1*01 | 0.90 | 0.41 | 0.60 | 6.84 | 2.07, 22.60 |
| ESR | 1.0 | 0.27 | 0.55 | — | — |
| CRP | 0.91 | 0.44 | 0.56 | 8.53 | 1.68, 43.3 |