Table 4

LMP2CfoI allelic frequencies in Mexican Mestizo with AS stratified by age at onset and history of AAU

LMP2-CfoI allele
A (%) B (%)
Guadalajara4-150
 Juveniles
  AAU+1  (25)3  (75)
  AAU−3 (10)27 (90)
 Adults
  AAU+6 (33.3)12 (66.7)
  AAU−21 (16.4)107 (83.6)
Mexico City4-151
 Juveniles
  AAU+8 (33.3)16 (66.7)
  AAU−14 (17.5)66 (82.5)
 Adults
  AAU+2 (33.3)4 (66.7)
  AAU−9 (18)41 (82)
  • 4-150 Stratified exact OR = 2.58 (95% CI, 0.80, 7.62; p = 0.12).

  • 4-151 Stratified exact OR = 2.31 (95% CI, 0.84, 6.12; p = 0.11).

  • Combined population stratified exact OR = 2.51 (95% CI, 1.21, 5.09; p = 0.013). OR = The exact conditional maximum likelihood estimates, stratified by age at onset of disease, for the odds ratio relating LMP2A allelic frequency and history of AAU.