Cox regression for discontinuation of treatment (univariate)
| Predictor (reference category) | All causes | Toxicity | Inefficacy | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | p Value | HR | 95% CI | p Value | HR | 95% CI | p Value | |||
| Type of AM (CQ) | 1.05 | 0.9, 1.3 | NS | 0.8 | 0.5, 1.1 | NS | 1.4 | 1.09, 1.9 | 0.01 | ||
| Sex (male) | NS | NS | 0.7 | 0.5, 0.9 | 0.02 | ||||||
| Age (<46) | 1.009 | 1.002, 1.01 | 0.005 | 1.9 | 1.4, 2.7 | 0.0001 | NS | ||||
| Disease duration (<2 y) | NS | NS | 1.3 | 1.02, 1.9 | NS | ||||||
| Physician (Rh 1) | NS | NS | NS | ||||||||
| Disease (RA) | NS | NS | — | — | 0.0001 | ||||||
| SLE | 0.3 | 0.1, 0.4 | 0.0001 | ||||||||
| PA | 0.6 | 0.4, 1.0 | 0.05 | ||||||||
| Other | 0.7 | 0.4, 1.2 | NS | ||||||||
| Rank (first) | 1.1 | 1.0, 1.2 | 0.002 | 0.6 | 0.4, 0.9 | 0.0003 | 0.6 | 0.4, 0.8 | 0.0001 | ||
HR = hazard ratio.