Reason for discontinuation of AM in total (and by drug)
| AM n (%) | CQ n (%) | HCQ n (%) | |
|---|---|---|---|
| Total receiving therapy | 940 | 541 (58) | 399 (42) |
| Total discontinued | 472 (50) | 290 (54) | 182 (46) |
| Toxicity | 145 (15) | 97 (18) | 48 (12) |
| Inefficacy | 175 (19) | 93 (17) | 82 (21) |
| Other causes | 152 (16) | 100 (18) | 52 (13) |
| no longer needed | 27 (3) | 17 (3) | 10 (3) |
| by patient | 63 (7) | 44 (8) | 19 (5) |
| pregnancy | 14 (2) | 12 (2) | 2 (0.5) |
| concomitant disease | 19 (2) | 12 (2) | 7 (2) |
| other | 6 (0.6) | 2 (0.4) | 4 (1) |
| unknown | 23 (2) | 13 (2) | 10 (3) |