Patient category | Total (n=188) | Haematogenous infection of native joints (n=101) | Haematogenous infection of joints with prosthetic or osteosynthetic material (n=25) | Direct infection of native joints (n=29) | Direct infection of joints with prosthetic or osteosynthetic material (n=33) |
Children | 38 | 36 | - | 2 | - |
Previously healthy | 31 | 29 | 2 | ||
Concomitant disease1-150 | 7 | 7 | |||
Adults, previously healthy | 23 | 16 | - | 7 | - |
Adults, immunocompromised1-151 | 38 | 321-153 | - | 6 | - |
Adults with joint disorders: | 63 | 8 | 15 | 13 | 27 |
Osteoarthritis | 28 | 5 | 8 | 4 | 11 |
Rheumatoid arthritis | 13 | 2 | 5 | 1 | 5 |
Ankylosing spondylitis | 1 | 1 | |||
Psoriatic arthritis | 1 | 1 | |||
Juvenile chronic arthritis | 1 | 1 | |||
History of joint trauma | 18 | 1 | 2 | 7 | 8 |
History of tuberculous coxitis | 1 | 1 | |||
Adults, with joint disorders and immunocompromised1-152 | 26 | 9 | 10 | 1 | 6 |
Osteoarthritis | 4 | 2 | 2 | ||
Rheumatoid arthritis | 19 | 6 | 10 | 3 | |
History of joint trauma | 3 | 1 | 1 | 1 |
↵1-150 Sickle cell trait in two cases; bronchial asthma with eczema, Duchenne’s muscular dystrophy, history of cardiosurgery, impaired killing capacity of neutrophils and impaired chemotaxis of neutrophils, each in one case.
↵1-151 Intravenous drug abuse in 14 (six HIV infected), diabetes mellitus in 11, renal insufficiency in three (two requiring regular dialysis), hematological malignancy in three, AIDS in two and chronic osteomyelitis in two cases. In one cases each: polymyalgia rheumatica treated with prednisone, chronic obstructive lung disease intermittently treated with prednisone, leprosy and alcohol abuse.
↵1-152 Diabetes mellitus in six, breast cancer in four, renal insufficiency in one, and immunosuppressive medication (prednisone, methotrexate or azathioprine) in 18 cases.
↵1-153 Two patients, both intravenous drug misusers, had each two episodes of bacterial arthritis.