Knee joint synovial fluid content of aggrecan, cartilage oligomeric matrix protein (COMP), and bone sialoprotein (BSP) in the first sample obtained from each patient. Values are median (range)
| Destructive group2-150 | Non-destrucctive group2-150 |
Differnce (P value) | |
| Aggrecan (mg 1−1) | 68.6 (13.8 to 198.1) | 31.4 (6.1 to 91.4) | 0.0005 |
| COMP (mg 1−1) | 56.4 (14.4 to 84.6) | 52.2 (28.7 to 115.0) | 0.95, NS |
| Aggrecan/COMP concentration ratio | 1.12 (0.47 to 3.54) | 0.58 (0.12 to 1.77) | 0.00004 |
| BSP (μg 1−1) | 355.2 (200 to 510.8) | 310.1 (72.0 to 534.4) | 0.33, NS |
↵2-150 Destructive group n=18, non-destructive group n=25.