Disease
|
Aim of treatment
|
Example of treatment
|
AA amyloidosis | Suppress acute phase response (Monitor serum amyloid A protein) | Immunosuppression in rheumatoid arthritis, juvenile rheumatoid arthritis (for example, chlorambucil). Colchicine for familial Mediterranean fever. Surgery for resistant osteomyelitis, and rare cytokine producing tumours |
AL amyloidosis | Suppress production of monoclonal immunoglobulin light chains | Chemotherapy for myeloma and monoclonal gammopathy |
Hereditary amyloidosis | Eliminate source of genetically variant protein | Orthotopic liver transplantation for variant transthyretin associated familial amyloid polyneuropathy |
Haemodialysis amyloidosis | Reduce plasma concentration of β2M | Renal transplantation |