Table 2

Immunohistochemical staining of components of the plasminogen activation system in normal synovia and synovia of OA and RA patients

uPA uPAR tPA PAI-1
Normal+/− LC+ LC, EC+/− LC
+ EC
OA+ LC
+/− EC, IC
+/− LC+ LC, EC+ LC, EC
RA+ LC, EC, IC+ LC, IC+ LC, EC+ LC, EC
  • − = No expression, +/− = weak expression, + = moderate to strong expression. LC = synovial lining cells, IC = interstitial cells, EC = endothelial.