Table 4

Treatment of intractable diarrhoea caused by secondary amyloidosis in 24 rheumatoid arthritis patients

Patient IVH IVH duration (days) CS maximum dose (md/day)* CS pulse Duration of diarrhoea (days) Duration of pulse (days) Outcome§
1+3520D
210S
3+4410S
4+7310M1254217S
5+8720S
630S
75S
+4025S
+2120M1259214D
80S
9+3315S
10+7620S
+3920D
11+18220B10016611S
+6420B1006623S
12+22310B1002533S
13+1515D
14+5120B1003050S
15+2720D
16+3710D
17+417M12534D
18+4010S
19+3010M1251729S
200S
2110M125593S
22+565S
23+2920M1253011S
24+5020B1001917S
  • IVH=intravenous hyperalimentation, CS=corticosteroid, M125=methylprednisolone 125 mg × 3 days, B100=betamethazone 100 mg × 3 days, S=survival, D=death. *Maximum daily dose of prednisolone.Duration of diarrhoea before start of corticosteroid pulse treatment.Duration of diarrhoea after the end of corticosteroid pulse treatment. §Outcome of patient during the course of intractable diarrhoea. Denotes transition from intractable diarrhoea to intestinal pseudo-obstruction before death.