Second line drug | Number of patients | Median dose of resumed treatment (range) |
Chloroquine | 10 | 700 (400 to 1400) mg/week |
Hydroxy-chloroquine | 15 | 2800 (1400 to 4200) mg/week |
Parenteral gold | 10 | 1300 (130 to 2600) mg/year |
d-Penicillamine | 4 | 250 (250 to 600) mg/day |
Sulphasalazine | 8 | 2000 (1500 to 2000) mg/day |
Azathioprine | 2 | 125 (100 to 150) mg/day |
Methotrexate | 2 | 7.5 (7.5 to 7.5) mg/week |