Table 2

Significant differences in regional cerebral blood flow responses to the suffering and intensity components of pain (painful heat—non-painful heat) between the group of patients with active RA and normal controls (all Z scores denote an increased response in the control group compared with the RA group). Z scores indicate the normal deviate for each location

Region		Side		Coordinates		Z score
Region		Side		x	y	Z score	z
	Female controls versus rheumatoid arthritis
Prefrontal cortex (area 10)	R	26	40	12	3.190
Cingulofrontal transition cortex (area 32)	R	18	32	16	2.990
Anterior cingulate cortex (area 24)	L	−12	2	40	2.690

See Table 1 for details of coordinate system.