Etidronate/placebo | Etidronate/NaF | |
Serum | ||
Creatinine (50-140 μmol/l) | 106 (47) | 106 (32) |
Calcium (2.20-2.60 mmol/l) | 2.41 (0.10) | 2.46 (0.18) |
Phosphorus (0.80-1.50 mmol/l) | 0.94 (0.21) | 0.98 (0.18) |
CRP (< 8 mg/l) | 14 (23) | 13 (17) |
ESR (< 10 mm/1h) | 30 (22) | 28 (23) |
AP (27-93 U/l) | 60 (20) | 74 (33) |
BAP (14-43 U/l) | 15.1 (8.3) | 22.6 (14.2) |
Osteocalin (12.9-55.9 ng/ml) | 15.3 (9.2) | 20.4 (10.7) |
P1CP (50-220 μg/l) | 103 (48) | 112 (34) |
1CTP (1.7-5.0 μg/l) | 5.1 (2.6) | 5.6 (2.5) |
25 Vitamin D (< 15 μg/l) | 20.2 (10.6) | 21.9 (12.8) |
Urine | ||
Calcium (< 0.50 mmol/mol creatine) | 0.42 (0.30) | 0.33 (0.28) |
Hydroxyproline (< 30 μmol/mol creatine) | 14.3 (19.6) | 20.4 (9.1) |
Pyridinoline, total (13.5-53.2 μmol/mol creatine) | 55 (42) | 46 (23) |
Deoxypyridinoline, total (2.2-27.6 μmol/mol creatine) | 13.6 (9.8) | 12.4 (4.0) |
Data shown as mean with normal range in parentheses. No statistically significant differences at baseline were found between the two groups.