TY - JOUR T1 - 2018 update of the EULAR recommendations for the management of Behçet’s syndrome JF - Annals of the Rheumatic Diseases JO - Ann Rheum Dis SP - 808 LP - 818 DO - 10.1136/annrheumdis-2018-213225 VL - 77 IS - 6 AU - Gulen Hatemi AU - Robin Christensen AU - Dongsik Bang AU - Bahram Bodaghi AU - Aykut Ferhat Celik AU - Farida Fortune AU - Julien Gaudric AU - Ahmet Gul AU - Ina Kötter AU - Pietro Leccese AU - Alfred Mahr AU - Robert Moots AU - Yesim Ozguler AU - Jutta Richter AU - David Saadoun AU - Carlo Salvarani AU - Francesco Scuderi AU - Petros P Sfikakis AU - Aksel Siva AU - Miles Stanford AU - Ilknur Tugal-Tutkun AU - Richard West AU - Sebahattin Yurdakul AU - Ignazio Olivieri AU - Hasan Yazici Y1 - 2018/06/01 UR - http://ard.bmj.com/content/77/6/808.abstract N2 - Several new treatment modalities with different mechanisms of action have been studied in patients with Behçet’s syndrome (BS). The aim of the current effort was to update the recommendations in the light of these new data under the auspices of the European League Against Rheumatism (EULAR) Standing Committee for Clinical Affairs. A task force was formed that included BS experts from different specialties including internal medicine, rheumatology, ophthalmology, dermatology, neurology, gastroenterology, oral health medicine and vascular surgery, along with a methodologist, a health professional, two patients and two fellows in charge of the systematic literature search. Research questions were determined using a Delphi approach. EULAR standardised operating procedures was used as the framework. Results of the systematic literature review were presented to the task force during a meeting. The former recommendations were modified or new recommendations were formed after thorough discussions followed by voting. The recommendations on the medical management of mucocutaneous, joint, eye, vascular, neurological and gastrointestinal involvement of BS were modified; five overarching principles and a new recommendation about the surgical management of vascular involvement were added. These updated, evidence-based recommendations are intended to help physicians caring for patients with BS. They also attempt to highlight the shortcomings of the available clinical research with the aim of proposing an agenda for further research priorities. ER -