PT  - JOURNAL ARTICLE
AU  - K De Ceulaer
AU  - M A Khamashta
AU  - E N Harris
AU  - G R Serjeant
AU  - G R Hughes
TI  - Antiphospholipid antibodies in homozygous sickle cell disease.
AID  - 10.1136/ard.51.5.671
DP  - 1992 May 01
TA  - Annals of the Rheumatic Diseases
PG  - 671--672
VI  - 51
IP  - 5
4099  - http://ard.bmj.com/content/51/5/671.short
4100  - http://ard.bmj.com/content/51/5/671.full
SO  - Ann Rheum Dis1992 May 01; 51
AB  - Serum samples from 108 unselected Jamaican patients with homozygous sickle cell disease and 116 control subjects with normal haemoglobin were screened for the presence of antiphospholipid antibodies. Slightly increased levels of IgG antiphospholipid antibodies were found in nine patients with sickle cell disease and in none of the control subjects. Serial control samples confirmed the increased levels of antiphospholipid antibodies. A comparison of the haematological and clinical features of patients with positive and negative antiphospholipid sickle cell disease did not highlight any differences between the groups.