HLA antigens in sarcoidosis

Clin Exp Immunol. 1977 Feb;27(2):227-9.

Abstract

The HLA antigens were identified in sixty-five patients with sarcoidosis, comprising forty-five with uveitis, twelve with erythema nodosum and eight with arthritis. In the group with arthritis, B8 was present in seven of eight (P = 0-0016) and the haplotype 1,8 in five of eight (P = 0-0053). A1 was present in 44% with uveitis (P = 0-04). There was no other significant disturbance of antigen frequencies in uveitis or in erythema nodosum, but it was noteworthy that B27 was present in only two patients with uveitis.

MeSH terms

  • Arthritis / immunology
  • Erythema Nodosum / immunology
  • HLA Antigens*
  • Histocompatibility Antigens*
  • Humans
  • Sarcoidosis / immunology*
  • Uveitis / immunology

Substances

  • HLA Antigens
  • Histocompatibility Antigens