Criteria for diagnosis of Behçet's disease. International Study Group for Behçet's Disease

Lancet. 1990 May 5;335(8697):1078-80.

Abstract

5 sets of criteria for diagnosis of Behçet's disease are in use--a problem which has hindered interpretation of different studies and collaborative research. An international study group, which included at least one proponent of 4 of the sets, was formed to derive new, internationally agreed diagnostic criteria for Behçet's disease. Data on 914 patients with Behçet's disease, from 12 centres in 7 countries, were compared with controls from the same centres. The new set of diagnostic criteria--which requires the presence of oral ulceration plus any two of genital ulceration, typical defined eye lesions, typical defined skin lesions, or a positive pathergy test--was simpler to use and had an improved discriminatory performance than its predecessors.

Publication types

  • Clinical Trial
  • Comparative Study
  • Multicenter Study
  • Review

MeSH terms

  • Algorithms
  • Behcet Syndrome / complications
  • Behcet Syndrome / diagnosis*
  • Eye Diseases / etiology
  • Female
  • Genital Diseases, Female / etiology
  • Genital Diseases, Male / etiology
  • Humans
  • Male
  • Multicenter Studies as Topic
  • Predictive Value of Tests
  • Recurrence
  • Reference Standards
  • Sampling Studies
  • Skin Tests
  • Skin Ulcer / etiology
  • Stomatitis, Aphthous / etiology
  • Ulcer / etiology