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18250112,18633127,17308859,25392987,12209479,15516011,12188443,18975369,9849314,18701554,27391386,21796116,16601538,25314636,23457380,15980902,2102029,1406482,6762236,27936522,22052584,19286847,18546882,16783857,11821994,22488501,8178077,19485724,10050628,19585722,16339094,9512972,24560169,18409523,21724706,22549879,21833886,28205336,991731,25519877,7033016,27109450,19447778,24685969,22582566,16339099,23858803,26190562,2239590,21654265,8146793,21617552,15589427,19339925,511087,16377385,978666,27010159,18559233,18431090,23391676,21050952,19048458,17328081,27926541,17013833,22132950,25495503,19141576,27821644,22223180,525067,31477161,8842764,9439546,24307655,17697859,25807090,782809,21285173,28314755,457017,18636784,29165620,20506124,9598024,11876034,21353107,25547991,31317680,15980907,6633222,23978312,21279998,26771445,17897242,21898351,25615006,35795968,11212165,28823114,857138,101792,11296962,25963969,20617751,3589999,338280,32301360,31533805,29733441,17223663,30615649,28320765,20464796,21846852,18759308,28202260,11177768,19543895,332605,24925693,25180128,27605442,10920575,26013187,976920,3330140,21572152,31353871,28379501,35229198,33181081,20500048,23681955,25180126,18422564,11063179,22539486,6862346,5509800,23098865,32483927,19734730,7221794,9799074,7042900,21265967,897378,18975368,7871619,27927043,17130343,29268756,17388867,2681764,34927391,26233513,2080622,17047891,539082,4949305,20696962,18225332,28830881,30426652,11894180,29496000,18271232,16259349,23121270,26751377,22132953,27832384,26989892,16958189,33771758,32483906,5712110,14631540,24940666,3900392,24899662,19078356,23485476,16482645,25512479,29733447,34508567,24259601,9465329,26451524,30107437,3599002,1206675,20631196,9500573,6686776,5469423,3909489,18349751,7245774,20722028,25373449,8976121,7660906,816095,21849262,21862966,31980978,16881370,21916803,15290738,19999896,680625,22948225,335500,5710881,6873850,6530890,20463191,19327147,5234549,17919772,31416925,22156509,18420531,761542,17910294,29566736,17059911,891391,7848545,7043937,705170,21271794,31891407,19369457,27449546,22795277,16835972,488877,4439104,2623976,20561096,8230024,18465047,689495,7655872,17896799,18600509,11096285,9374937,19332629,18193917,9492630,17596042,28028194,7221944,15049403,5394966,19695386,2801716,21812496,11579724,30503879,918777,19463070,12522834,578444,8976102,26453097,11128679,8436158,5675122,25876828,4219708,24851021,26113027,437646,8618639,6861811,661730,19695403,6896252,16602151,11510209,16478808,30915866,5990726,9500766,31286139,30304329,1941830,28544467,24286500,7372248,26742777,4659072,15570646,25028379,19539099,30343856,25644128,5701049,19302899,36317407,16463619,30244431,17065067,22456297,26810134,8035396,628361,867154,3728165,4806417,30446002,23392592,26977497,9434564,1265467,5335059,28365572,30176211,17325024,23932726,5958699,6637745,2711778,31140959,16166134,33604505,17610315,25180130,22839705,28411137,25275760,32767502,24719620,7482890,6999575,33211886,1771852,1164458,29251661,19787189,30394337,5754904,31444839,15534635,2068454,4816858,29042386,16835310,11108066,17998214,17907217,25451835,305012,8832991,9375898,16498814,16598054,25331310,35629121,14687901,16953466,25152400,19696695,11889674,1172813,137686,36036279,17263196,306273,18266852,17349440,27894951,6999850,26077411,15229971,8336619,6994191,7171423,15985055,19448587,27591828,31476243,31391099,12629718,29123379,4978717,33521512,16913436,18557715,8523332,10192993,26387388,331478,4448143,7065639,23281274,10803751,22675142,16267879,7278572,9392688,6206519,36749254,9598031,32841190,5667553,2042555,23350244,5704850,7219341,23756530,17034470,1197959,3178870,23873481,5684610,21169857,9014485,24413343,11938622,4464994,5513199,26150126,23669799,26554739,17014020,21393610,23436266,18822021,28631693,5486126,867395,30575597,18282776,3275178,18640465,8090336,34779393,21295195,5748155,34406530,19369467,24395556,7392938,5621168,19698011,388398,3780828,7372221,3235015,11096905,5258764,4826801,757280,5131996,1259799,5569433,20690341,2067100,17113968,5947301,35966182,5597941,29133496,17058902,30478125,25162087,4413595,10334688,32286732,15912988,22235497,22345034,996556,11557658,7400372,6054472,1209378,33378761,344175,6075623,10895280,18344696,17728328,30845099,15788888,5765127,1093064,3815469,5723559,17064528,5599222,934016,8208488,31438085,1263801,903059,26170376,434944,663791,17650804,17132810,5818966,10750078,7278540,16979531,32265121,9651090,23590252,7433031,436143,10573316,1747133,35169055,18759307,22472359,12362184,5621966,19077754,17367691,9797577,4216779,26276048,5090544,10214039,5715143,4656975,17121496,685512,17587850,9678437,5622944,25898174,5485958,4805462,20472590,29272508,7072257,3590000,923626,31256872,31150161,15493119,28597919,3573681,4292983,16943372,22313089,7385782,4948390,29342288,6853140,3172103,16265700,35772867,16795900,37000552,21372003,11453075,27068619,5762750,4937597,37127506,23728186,15732163,645192,5285423,17059912,30845096,6890841,27639692,31683330,27683090,27296322,4946002,21329621,346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Results by year

Year	Number of Results
1785	1
1951	1
1952	2
1953	3
1954	7
1955	8
1956	4
1957	10
1958	2
1959	3
1960	1
1961	1
1962	4
1963	6
1965	4
1966	8
1967	22
1968	23
1969	15
1970	10
1971	13
1972	4
1973	4
1974	11
1975	9
1976	17
1977	18
1978	16
1979	16
1980	15
1981	13
1982	15
1983	10
1984	3
1985	6
1986	12
1987	8
1988	7
1989	10
1990	6
1991	9
1992	4
1993	3
1994	8
1995	9
1996	9
1997	5
1998	13
1999	9
2000	11
2001	11
2002	12
2003	9
2004	12
2005	15
2006	40
2007	36
2008	31
2009	30
2010	13
2011	28
2012	22
2013	23
2014	29
2015	28
2016	28
2017	33
2018	23
2019	24
2020	21
2021	18
2022	17
2023	9
2024	0

886 results

Page of 89

Results by year

Page 1

Efficacy and tolerability of urate-lowering drugs in gout: a randomised controlled trial of benzbromarone versus probenecid after failure of allopurinol.

Reinders MK, van Roon EN, Jansen TL, Delsing J, Griep EN, Hoekstra M, van de Laar MA, Brouwers JR. Reinders MK, et al. Ann Rheum Dis. 2009 Jan;68(1):51-6. doi: 10.1136/ard.2007.083071. Epub 2008 Feb 4. Ann Rheum Dis. 2009. PMID: 18250112 Clinical Trial.

A randomised controlled trial on the efficacy and tolerability with dose escalation of allopurinol 300-600 mg/day versus benzbromarone 100-200 mg/day in patients with gout.

Reinders MK, Haagsma C, Jansen TL, van Roon EN, Delsing J, van de Laar MA, Brouwers JR. Reinders MK, et al. Ann Rheum Dis. 2009 Jun;68(6):892-7. doi: 10.1136/ard.2008.091462. Epub 2008 Jul 16. Ann Rheum Dis. 2009. PMID: 18633127 Clinical Trial.

Biochemical effectiveness of allopurinol and allopurinol-probenecid in previously benzbromarone-treated gout patients.

Reinders MK, van Roon EN, Houtman PM, Brouwers JR, Jansen TL. Reinders MK, et al. Clin Rheumatol. 2007 Sep;26(9):1459-65. doi: 10.1007/s10067-006-0528-3. Epub 2007 Feb 17. Clin Rheumatol. 2007. PMID: 17308859 Clinical Trial.

Uricosuric medications for chronic gout.

Kydd AS, Seth R, Buchbinder R, Edwards CJ, Bombardier C. Kydd AS, et al. Cochrane Database Syst Rev. 2014 Nov 14;(11):CD010457. doi: 10.1002/14651858.CD010457.pub2. Cochrane Database Syst Rev. 2014. PMID: 25392987

Effect of urate-lowering therapy on the velocity of size reduction of tophi in chronic gout.

Perez-Ruiz F, Calabozo M, Pijoan JI, Herrero-Beites AM, Ruibal A. Perez-Ruiz F, et al. Arthritis Rheum. 2002 Aug;47(4):356-60. doi: 10.1002/art.10511. Arthritis Rheum. 2002. PMID: 12209479 Free article. Clinical Trial.

The efficacy of combined low dose of Allopurinol and benzbromarone compared to standard dose of Allopurinol in hyperuricemia.

Akkasilpa S, Osiri M, Deesomchok U, Avihingsanon Y. Akkasilpa S, et al. J Med Assoc Thai. 2004 Sep;87(9):1087-91. J Med Assoc Thai. 2004. PMID: 15516011

Efficacy of benzbromarone compared to allopurinol in lowering serum uric acid level in hyperuricemic patients.

Hanvivadhanakul P, Akkasilpa S, Deesomchok U. Hanvivadhanakul P, et al. J Med Assoc Thai. 2002 Jun;85 Suppl 1:S40-7. J Med Assoc Thai. 2002. PMID: 12188443 Clinical Trial.

Effects of febuxostat versus allopurinol and placebo in reducing serum urate in subjects with hyperuricemia and gout: a 28-week, phase III, randomized, double-blind, parallel-group trial.

Schumacher HR Jr, Becker MA, Wortmann RL, Macdonald PA, Hunt B, Streit J, Lademacher C, Joseph-Ridge N. Schumacher HR Jr, et al. Arthritis Rheum. 2008 Nov 15;59(11):1540-8. doi: 10.1002/art.24209. Arthritis Rheum. 2008. PMID: 18975369 Free article. Clinical Trial.

Efficacy of allopurinol and benzbromarone for the control of hyperuricaemia. A pathogenic approach to the treatment of primary chronic gout.

Perez-Ruiz F, Alonso-Ruiz A, Calabozo M, Herrero-Beites A, García-Erauskin G, Ruiz-Lucea E. Perez-Ruiz F, et al. Ann Rheum Dis. 1998 Sep;57(9):545-9. doi: 10.1136/ard.57.9.545. Ann Rheum Dis. 1998. PMID: 9849314 Free PMC article. Clinical Trial.

Opportunities for improving medication use and monitoring in gout.

Singh JA, Hodges JS, Asch SM. Singh JA, et al. Ann Rheum Dis. 2009 Aug;68(8):1265-70. doi: 10.1136/ard.2008.092619. Epub 2008 Aug 13. Ann Rheum Dis. 2009. PMID: 18701554

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