The role of interleukin-1 and the inflammasome in gout: implications for therapy

Arthritis Rheum. 2007 Oct;56(10):3183-8. doi: 10.1002/art.22938.
No abstract available

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Arthritis, Gouty / immunology*
  • Arthritis, Gouty / physiopathology
  • Carrier Proteins / immunology
  • Colchicine / pharmacology
  • Gout / immunology
  • Gout Suppressants / pharmacology
  • Humans
  • Hyperuricemia / immunology
  • Inflammation / physiopathology
  • Interleukin-1beta / biosynthesis*
  • Macrophages / drug effects
  • Monocytes / drug effects
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • Signal Transduction
  • Toll-Like Receptors / immunology
  • Uric Acid / metabolism

Substances

  • Carrier Proteins
  • Gout Suppressants
  • Interleukin-1beta
  • NLR Family, Pyrin Domain-Containing 3 Protein
  • NLRP3 protein, human
  • Toll-Like Receptors
  • Uric Acid
  • Colchicine