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12810425,12847684,11350843,16728461,11508425,10693865,12571842,15476228,12209505,11792884,9778216,10834861,15188355,16207318,12571844,15457463,11592363,16173240,11508424,27424032,16507143,27733582,11062605,15229943,11561108,16200598,12379519,14558086,12687542,11908553,12563678,11406520,22076945,11840439,17763446,18203309,19883500,8814070,17009243,11857499,15667572,9692066,15146416,12508384,11219391,15198385,21816022,18055470,9884354,12509625,11959761,11289656,16872482,19678938,11824946,11346728,16205926,10834863,9667617,12011369,10493666,12384916,17105646,17177994,10857783,10643698,11035124,16507118,20678708,14611107,15731292,17426140,12517948,11759230,23224392,10544841,18276742,15593217,17223661,10946307,12228167,29394098,9972954,11920402,16414969,10943872,29328500,20374310,24982240,10529123,16311048,12794819,24440992,16449361,26658436,19479862,11709608,33679701,15743468,10334680,20665024,32431716,10617637,15320915,24309559,21385358,12009332,10556258,9764613,22264498,31978425,12634226,19248098,9236673,11808986,8546529,32131874,11115151,9014820,22824140,9870691,16277668,10211878,8311554,19826823,15540281,11710707,9440147,21658319,22212411,23006144,20439288,25031723,9461144,34887865,11560279,19627579,8356391,7686370,19426483,11561106,3258750,10494903,11665967,12594102,12695157,12694700,20636397,12586482,8017985,12114504,9041933,11285370,8919199,8129774,18256870,8356394,9034998,10587545,21272347,8898888,1448746,33329580,11087697,22767598,10333199,21730088,14607859,8546721,10402070,33427511,23370854,17903238,8311538,8778952,12296865,9918530,9232430,15879156,8546720,16627543,21909699,9259418,10531073,12525378,11160347,18292234,27696338,16146751,21345222,2675782,19415460,23956247,10371281,10404054,19037609,19226472,18660510,22494514,11312372,20108506,8574962,12634225,22661088,36326383,31487484,9376987,18727628,25858640,34645250,3547269,20589975,10517187,9569072,10662872,15366668,12810159,10102645,7614736,9416849,32393826,21913037,15693006,23826419,24066520,9562516,9683554,8129777,1393370,7492239,18473901,29409140,1374550,22656185,9783767,31072400,9385356,10803746,10994772,12006318,26097225,10340958,24574210,17951651,1967122,34685605,19196489,12269994,2787183,1657008,17425385,11954885,9259419,9259421,8792801,19596176,35008858,31186464,35653890,26792343,12058953,1279786,22718219,20193003,9228535,33968050,1958087,20105279,10531072,31320744,11312384,11925532,22179929,3493780,9640131,18633630,9590334,22734971,9659224,14597251,29439295,17951661,12860725,14583574,12417058,33107629,19660107,8343185,18214499,19497113,11171698,11953992,2257448,34220809,20304957,27450196,29891556,19378024,18647851,19593575,11377461,32557565,1371728,1980561,27863512,17545191,31497022,30630515,29579371,30357805,1085094,3075089,10491366,2481879,11762950,10928772,1329776,7504437,23377799,22574210,32840301,12784911,3264935,15046450,9828857,22409996,25163744,7683454,3548731,15814737,10638766,8153072,1099958,17963503,23098925,7679713,7939726,1384441,9416577,21262368,7677442,3314876,24942296,8202661,7575695,9133962,25147433,18369645,10622476,11136879,9566675,10778801,8625558,19956574,1082748,2786697,24108368,1124957,7612414,9509762,8796980,2457377,17951672,3968518,12010605,9184845,31784384,17951655,23840241,35296975,4545206,35592852,929119,35410356,3258751,30574751,33226449,35967291,2205906,6377451,1570520,11600741,21887369,2353357,12716448,34716857,30371936,6605750,8714431,1772295,1316742,10381487,11371660,9699841,27383913,11564829,23675020,21776443,30754994,21109518,10507305,23951325,2968782,20510236,18289056,10318942,29996944,7901286,6336086,35255378,1628162,33374446,9836371,25140813,31831833,30552174,30075744,7934515,18439312,30718650,29665766,33069194,20025584,10913062,1445692,1057866,36244795,35084317,29315512,11934970,16081832,8370165,29974224,30018954,8608350,33183053,11932042,10419868,8457225,1626285,8546734,8727714,6356908,19160981,7458429,28662826,10833466,3251351,10534574,10199746,32483659,18414968,31865803,8608348,24722995,6376325,35672464,3075077,12810431,36985456,9619953,8774184,19077955,7830475,10412569,12461081,7531440,14517450,19585131,10706681,12224862,3486592,33148884,11890208,12527218,11001373,29285051,11173599,34021673,31068444,14871458,2802794,7552064,33476818,17540510,7436557,2510332,10415789,8003048,11357166,7575729,18071707,20443906,10371277,30347191,305451,36799236,24631368,24286442,11336920,9255107,7986219,19395871,7702413,29998825,9122163,10727770,25332857,7020614,3524146,19007422,17898090,32519204,33898490,28518078,3257873,19491913,35958604,31921178,7939732,12498813,15103248,16112560,17951670,28737753,26749303,2198976,21542897,1866570,35678661,28425031,12056291,10577972,3814968,12379515,7725071,35384879,27183538,31895885,4357332,8916295,22905907,11142719,10913056,11147175,51603,33014110,9125268,2194461,11085795,10392518,6275499,12009565,8787634,31785142,20067598,6188207,31480453,34691030,25405084,11774572,33187941,8526082,15777203,8651965,1599815,4116086,5728096,14714889,23819059,21054095,35847785,7978846,8792803,2256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Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic synovial biopsies: comparison with synovial samples from patients with end stage, destructive rheumatoid arthritis.

Smeets TJ, Barg EC, Kraan MC, Smith MD, Breedveld FC, Tak PP. Smeets TJ, et al. Ann Rheum Dis. 2003 Jul;62(7):635-8. doi: 10.1136/ard.62.7.635. Ann Rheum Dis. 2003. PMID: 12810425 Free PMC article.

Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy.

Andreakos E, Smith C, Kiriakidis S, Monaco C, de Martin R, Brennan FM, Paleolog E, Feldmann M, Foxwell BM. Andreakos E, et al. Arthritis Rheum. 2003 Jul;48(7):1901-12. doi: 10.1002/art.11044. Arthritis Rheum. 2003. PMID: 12847684 Free article.

Analysis of the cell infiltrate and expression of matrix metalloproteinases and granzyme B in paired synovial biopsy specimens from the cartilage-pannus junction in patients with RA.

Smeets TJ, Kraan MC, Galjaard S, Youssef PP, Smith MD, Tak PP. Smeets TJ, et al. Ann Rheum Dis. 2001 Jun;60(6):561-5. doi: 10.1136/ard.60.6.561. Ann Rheum Dis. 2001. PMID: 11350843 Free PMC article.

Detailed analysis of the cell infiltrate and the expression of mediators of synovial inflammation and joint destruction in the synovium of patients with psoriatic arthritis: implications for treatment.

van Kuijk AW, Reinders-Blankert P, Smeets TJ, Dijkmans BA, Tak PP. van Kuijk AW, et al. Ann Rheum Dis. 2006 Dec;65(12):1551-7. doi: 10.1136/ard.2005.050963. Epub 2006 May 25. Ann Rheum Dis. 2006. PMID: 16728461 Free PMC article.

Production of cytokines, vascular endothelial growth factor, matrix metalloproteinases, and tissue inhibitor of metalloproteinases 1 by tenosynovium demonstrates its potential for tendon destruction in rheumatoid arthritis.

Jain A, Nanchahal J, Troeberg L, Green P, Brennan F. Jain A, et al. Arthritis Rheum. 2001 Aug;44(8):1754-60. doi: 10.1002/1529-0131(200108)44:8<1754::AID-ART310>3.0.CO;2-8. Arthritis Rheum. 2001. PMID: 11508425 Free article.

The effects of interferon-beta treatment of synovial inflammation and expression of metalloproteinases in patients with rheumatoid arthritis.

Smeets TJ, Dayer JM, Kraan MC, Versendaal J, Chicheportiche R, Breedveld FC, Tak PP. Smeets TJ, et al. Arthritis Rheum. 2000 Feb;43(2):270-4. doi: 10.1002/1529-0131(200002)43:2<270::AID-ANR5>3.0.CO;2-H. Arthritis Rheum. 2000. PMID: 10693865 Free article.

Association of interleukin-18 expression with enhanced levels of both interleukin-1beta and tumor necrosis factor alpha in knee synovial tissue of patients with rheumatoid arthritis.

Joosten LA, Radstake TR, Lubberts E, van den Bersselaar LA, van Riel PL, van Lent PL, Barrera P, van den Berg WB. Joosten LA, et al. Arthritis Rheum. 2003 Feb;48(2):339-47. doi: 10.1002/art.10814. Arthritis Rheum. 2003. PMID: 12571842 Free article.

Reduction of synovial sublining layer inflammation and proinflammatory cytokine expression in psoriatic arthritis treated with methotrexate.

Kane D, Gogarty M, O'leary J, Silva I, Bermingham N, Bresnihan B, Fitzgerald O. Kane D, et al. Arthritis Rheum. 2004 Oct;50(10):3286-95. doi: 10.1002/art.20518. Arthritis Rheum. 2004. PMID: 15476228 Free article.

Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: Implications for pathogenesis and evaluation of treatment.

Kraan MC, Reece RJ, Smeets TJ, Veale DJ, Emery P, Tak PP. Kraan MC, et al. Arthritis Rheum. 2002 Aug;46(8):2034-8. doi: 10.1002/art.10556. Arthritis Rheum. 2002. PMID: 12209505 Free article.

Serum matrix metalloproteinases and tissue inhibitors of metalloproteinases in different histological variants of rheumatoid synovitis.

Klimiuk PA, Sierakowski S, Latosiewicz R, Cylwik B, Skowronski J, Chwiecko J. Klimiuk PA, et al. Rheumatology (Oxford). 2002 Jan;41(1):78-87. doi: 10.1093/rheumatology/41.1.78. Rheumatology (Oxford). 2002. PMID: 11792884

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