Editorials:

How to dose infliximab in rheumatoid arthritis: new data on a serious issue

Ronald F van Vollenhoven

Ann Rheum Dis 2009; 68: 1237-1239. doi:10.1136/ard.2009.111682

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Reviews:

European biologicals registers: methodology, selected results and perspectives

A Zink, J Askling, W G Dixon, L Klareskog, A J Silman, and D P M Symmons

Ann Rheum Dis 2009; 68: 1240-1246.
Published Online First: 22 July 2008. doi:10.1136/ard.2008.091926

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Letters:

STAT4 single nucleotide polymorphism, rs7574865 G/T, as a risk for antiphospholipid syndrome

T Horita, T Atsumi, N Yoshida, H Nakagawa, H Kataoka, S Yasuda, and T Koike

Ann Rheum Dis 2009; 68: 1366-1367. doi:10.1136/ard.2008.094367

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Dihydroorotate dehydrogenase polymorphism influences the toxicity of leflunomide treatment in patients with rheumatoid arthritis

P Bohanec Grabar, B Rozman, D Logar, S Praprotnik, and V Dolzan

Ann Rheum Dis 2009; 68: 1367-1368. doi:10.1136/ard.2008.099093

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A single course of rituximab does not abrogate anti-infliximab antibodies in patients with rheumatoid arthritis

B J F van den Bemt, K Vos, A A den Broeder, M Blom, R M Thurlings, G M Bartelds, S O Stapel, P Barrera, P P Tak, M T Nurmohamed, and G-J Wolbink

Ann Rheum Dis 2009; 68: 1368-1369. doi:10.1136/ard.2008.095448

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High-resolution MRI for assessment of middle meningeal artery involvement in giant cell arteritis

T A Bley, J Geiger, S Jacobsen, O Wieben, M Markl, P Vaith, T Grist, M Langer, and M Uhl

Ann Rheum Dis 2009; 68: 1369-1370. doi:10.1136/ard.2008.101816

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Optimalisation of the clinical pharmacogenetic model to predict methotrexate treatment response: the influence of the number of haplotypes of MTHFR 1298A–677C alleles on probability to respond

W M Kooloos, J A M Wessels, S M van der Kooij, C F Allaart, T W J Huizinga, and H-J Guchelaar

Ann Rheum Dis 2009; 68: 1371. doi:10.1136/ard.2008.096891

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Changes in surgical intervention patterns in rheumatoid arthritis over 10 years in one centre

C Kolling, D B Herren, B R Simmen, and J Goldhahn

Ann Rheum Dis 2009; 68: 1372-1373. doi:10.1136/ard.2008.100800

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A re-evaluation of three putative functional single nucleotide polymorphisms in rheumatoid arthritis

D Plant, A Barton, W Thomson, X Ke, S Eyre, A Hinks, J Bowes, L J Gibbons, A G Wilson, I Marinou, A W Morgan, S Steer, L J Hocking, D M Reid, P Wordsworth, P Harrison, and J Worthington

Ann Rheum Dis 2009; 68: 1373-1375. doi:10.1136/ard.2008.103572

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Association of STAT4 polymorphism with systemic sclerosis in a Japanese population

N Tsuchiya, A Kawasaki, M Hasegawa, M Fujimoto, K Takehara, Y Kawaguchi, M Kawamoto, M Hara, and S Sato

Ann Rheum Dis 2009; 68: 1375-1376. doi:10.1136/ard.2009.111310

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Basic and translational research:

Apolipoprotein A-I and platelet factor 4 are biomarkers for infliximab response in rheumatoid arthritis

C Trocmé, H Marotte, A Baillet, B Pallot-Prades, J Garin, L Grange, P Miossec, J Tebib, F Berger, M J Nissen, R Juvin, F Morel, and P Gaudin

Ann Rheum Dis 2009; 68: 1328-1333.
Published Online First: 29 July 2008. doi:10.1136/ard.2008.093153

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Expression of cathepsin K and matrix metalloproteinase 1 indicate persistent osteodestructive activity in long-standing ankylosing spondylitis

M Neidhart, X Baraliakos, C Seemayer, C Zelder, R E Gay, B A Michel, H Boehm, S Gay, and J Braun

Ann Rheum Dis 2009; 68: 1334-1339.
Published Online First: 4 August 2008. doi:10.1136/ard.2008.092494

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Evidence for association of an interleukin 23 receptor variant independent of the R381Q variant with rheumatoid arthritis

J E Hollis-Moffatt, M E Merriman, R A Rodger, K A Rowley, P T Chapman, N Dalbeth, P J Gow, A A Harrison, J Highton, P B B Jones, J L O’Donnell, L K Stamp, and T R Merriman

Ann Rheum Dis 2009; 68: 1340-1344.
Published Online First: 22 July 2008. doi:10.1136/ard.2008.090142

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Regulatory IL4+CD8+ T cells in patients with ankylosing spondylitis and healthy controls

L Zhang, L B Jarvis, H-J Baek, and J S Hill Gaston

Ann Rheum Dis 2009; 68: 1345-1351.
Published Online First: 22 July 2008. doi:10.1136/ard.2008.088120

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Human bone marrow mesenchymal stem cells and chondrocytes promote and/or suppress the in vitro proliferation of lymphocytes stimulated by interleukins 2, 7 and 15

C Bocelli-Tyndall, L Bracci, S Schaeren, C Feder-Mengus, A Barbero, A Tyndall, and G C Spagnoli

Ann Rheum Dis 2009; 68: 1352-1359.
Published Online First: 22 July 2008. doi:10.1136/ard.2008.094003

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Reversible changes in serum immunoglobulin galactosylation during the immune response and treatment of inflammatory autoimmune arthritis

K Van Beneden, K Coppieters, W Laroy, F De Keyser, I E Hoffman, F Van den Bosch, B Vander Cruyssen, M Drennan, P Jacques, P Rottiers, G Verbruggen, R Contreras, N Callewaert, and D Elewaut

Ann Rheum Dis 2009; 68: 1360-1365.
Published Online First: 4 September 2008. doi:10.1136/ard.2008.089292

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Clinical and epidemiological research:

Local delivery of a recombinant adenoassociated vector containing a tumour necrosis factor antagonist gene in inflammatory arthritis: a phase 1 dose-escalation safety and tolerability study

P J Mease, K Hobbs, A Chalmers, H El-Gabalawy, A Bookman, E Keystone, D E Furst, P Anklesaria, and A E Heald

Ann Rheum Dis 2009; 68: 1247-1254.
Published Online First: 4 August 2008. doi:10.1136/ard.2008.089375

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The sensitivity to change for lower disease activity is greater than for higher disease activity in rheumatoid arthritis trials

B Zhang, M Lavalley, and D T Felson

Ann Rheum Dis 2009; 68: 1255-1259.
Published Online First: 12 August 2008. doi:10.1136/ard.2008.092460

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Progression of hand osteoarthritis over 2 years: a clinical and radiological follow-up study

S Botha-Scheepers, N Riyazi, I Watt, F R Rosendaal, E Slagboom, N Bellamy, F C Breedveld, and M Kloppenburg

Ann Rheum Dis 2009; 68: 1260-1264.
Published Online First: 26 August 2008. doi:10.1136/ard.2008.087981

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Opportunities for improving medication use and monitoring in gout

J A Singh, J S Hodges, and S M Asch

Ann Rheum Dis 2009; 68: 1265-1270.
Published Online First: 13 August 2008. doi:10.1136/ard.2008.092619

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Disease activity as a risk factor for myocardial infarction in rheumatoid arthritis

B J Radovits, D A Popa-Diaconu, C Popa, A Eijsbouts, R F J M Laan, P L C M van Riel, and J Fransen

Ann Rheum Dis 2009; 68: 1271-1276.
Published Online First: 13 August 2008. doi:10.1136/ard.2008.089862

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Infliximab improves vascular stiffness in patients with rheumatoid arthritis

M Wong, S P Oakley, L Young, B Y Jiang, A Wierzbicki, G Panayi, P Chowienczyk, and B Kirkham

Ann Rheum Dis 2009; 68: 1277-1284.
Published Online First: 17 October 2008. doi:10.1136/ard.2007.086157

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Increasing the infliximab dose in rheumatoid arthritis patients: a randomised, double blind study failed to confirm its efficacy

K Pavelka, K Jarosová, D Suchy, L Senolt, K Chroust, L Dusek, and J Vencovsky

Ann Rheum Dis 2009; 68: 1285-1289.
Published Online First: 6 April 2009. doi:10.1136/ard.2008.090860

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Mechanisms of bone erosion in gout: a quantitative analysis using plain radiography and computed tomography

N Dalbeth, B Clark, K Gregory, G Gamble, T Sheehan, A Doyle, and F M McQueen

Ann Rheum Dis 2009; 68: 1290-1295.
Published Online First: 15 August 2008. doi:10.1136/ard.2008.094201

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Does low-field dedicated extremity MRI (E-MRI) reliably detect bone erosions in rheumatoid arthritis? A comparison of two different E-MRI units and conventional radiography with high-resolution CT scanning

A Duer-Jensen, B Ejbjerg, E Albrecht-Beste, A Vestergaard, U Møller Døhn, M Lund Hetland, and M Østergaard

Ann Rheum Dis 2009; 68: 1296-1302.
Published Online First: 21 August 2008. doi:10.1136/ard.2008.093591

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A prospective, randomised, placebo-controlled study to identify biomarkers associated with active treatment in psoriatic arthritis: effects of adalimumab treatment on synovial tissue

A W R van Kuijk, D M Gerlag, K Vos, G Wolbink, M de Groot, M A de Rie, A H Zwinderman, B A C Dijkmans, and P P Tak

Ann Rheum Dis 2009; 68: 1303-1309.
Published Online First: 22 July 2008. doi:10.1136/ard.2008.091389

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Proposal for a new clinical entity, IgG₄-positive multiorgan lymphoproliferative syndrome: analysis of 64 cases of IgG₄-related disorders

Y Masaki, L Dong, N Kurose, K Kitagawa, Y Morikawa, M Yamamoto, H Takahashi, Y Shinomura, K Imai, T Saeki, A Azumi, S Nakada, E Sugiyama, S Matsui, T Origuchi, S Nishiyama, I Nishimori, T Nojima, K Yamada, M Kawano, Y Zen, M Kaneko, K Miyazaki, K Tsubota, K Eguchi, K Tomoda, T Sawaki, T Kawanami, M Tanaka, T Fukushima, S Sugai, and H Umehara

Ann Rheum Dis 2009; 68: 1310-1315.
Published Online First: 13 August 2008. doi:10.1136/ard.2008.089169

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Sustained changes in lipid profile and macrophage migration inhibitory factor levels after anti-tumour necrosis factor therapy in rheumatoid arthritis

C A Wijbrandts, S I van Leuven, H D Boom, D M Gerlag, E G S Stroes, J J P Kastelein, and P P Tak

Ann Rheum Dis 2009; 68: 1316-1321.
Published Online First: 22 August 2008. doi:10.1136/ard.2007.086728

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Ultrasound validity in the measurement of knee cartilage thickness

E Naredo, C Acebes, I Möller, F Canillas, J J de Agustín, E de Miguel, E Filippucci, A Iagnocco, C Moragues, R Tuneu, J Uson, J Garrido, E Delgado-Baeza, and I Sáenz-Navarro

Ann Rheum Dis 2009; 68: 1322-1327.
Published Online First: 6 August 2008. doi:10.1136/ard.2008.090738

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