Editorials:

Arthritis and endogenous glucocorticoids: the emerging role of the 11β-HSD enzymes

Frank Buttgereit, Hong Zhou, and Markus J Seibel

Ann Rheum Dis 2008; 67: 1201-1203. doi:10.1136/ard.2008.092502

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Extended reports:

Local and systemic glucocorticoid metabolism in inflammatory arthritis

R Hardy, E H Rabbitt, A Filer, P Emery, M Hewison, P M Stewart, N J Gittoes, C D Buckley, K Raza, and M S Cooper

Ann Rheum Dis 2008; 67: 1204-1210.
Published Online First: 17 April 2008. doi:10.1136/ard.2008.090662

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Treatment with a CO-releasing molecule (CORM-3) reduces joint inflammation and erosion in murine collagen-induced arthritis

M L Ferrándiz, N Maicas, I Garcia-Arnandis, M C Terencio, R Motterlini, I Devesa, L A B Joosten, W B van den Berg, and M J Alcaraz

Ann Rheum Dis 2008; 67: 1211-1217.
Published Online First: 6 December 2007. doi:10.1136/ard.2007.082412

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Adalimumab effectively reduces the signs and symptoms of active ankylosing spondylitis in patients with total spinal ankylosis

D van der Heijde, A L Pangan, M H Schiff, J Braun, M Borofsky, J Torre, J C Davis, Jr, R L Wong, H Kupper, E Collantes, and for the ATLAS Study Group

Ann Rheum Dis 2008; 67: 1218-1221.
Published Online First: 4 December 2007. doi:10.1136/ard.2007.082529

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Long-term effects of bosentan on quality of life, survival, safety and tolerability in pulmonary arterial hypertension related to connective tissue diseases

C P Denton, J E Pope, H-H Peter, A Gabrielli, A Boonstra, F H J van den Hoogen, G Riemekasten, S De Vita, A Morganti, M Dölberg, O Berkani, L Guillevin, and (on behalf of the TRacleer Use in PAH associated with Scleroderma and Connective Tissue Diseases (TRUST) Investigators)

Ann Rheum Dis 2008; 67: 1222-1228.
Published Online First: 30 November 2007. doi:10.1136/ard.2007.079921

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The effectiveness and medication costs of three anti-tumour necrosis factor agents in the treatment of rheumatoid arthritis from prospective clinical practice data

W Kievit, E M Adang, J Fransen, H H Kuper, M A F J van de Laar, T L Jansen, C M A De Gendt, D-J R A M De Rooij, H L M Brus, P C M Van Oijen, and P C L M Van Riel

Ann Rheum Dis 2008; 67: 1229-1234.
Published Online First: 3 January 2008. doi:10.1136/ard.2007.083675

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Modulation of established murine collagen-induced arthritis by a single inoculation of short-term lipopolysaccharide-stimulated dendritic cells

L Salazar, O Aravena, P Abello, A Escobar, J Contreras-Levicoy, N Rojas-Colonelli, D Catalán, A Aguirre, R Zúñiga, B Pesce, C González, R Cepeda, M Cuchacovich, M C Molina, F Salazar-Onfray, M Delgado, R E Toes, and J C Aguillón

Ann Rheum Dis 2008; 67: 1235-1241.
Published Online First: 4 December 2007. doi:10.1136/ard.2007.072199

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COMP: a candidate molecule in the pathogenesis of systemic sclerosis with a potential as a disease marker

R Hesselstrand, A Kassner, D Heinegård, and T Saxne

Ann Rheum Dis 2008; 67: 1242-1248.
Published Online First: 7 December 2007. doi:10.1136/ard.2007.082099

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High bone turnover is associated with accelerated bone loss but not with increased fracture risk in men aged 50 and over: the prospective MINOS study

P Szulc, A Montella, and P D Delmas

Ann Rheum Dis 2008; 67: 1249-1255.
Published Online First: 7 December 2007. doi:10.1136/ard.2007.077941

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Association between leptin, body composition, sex and knee cartilage morphology in older adults: the Tasmanian older adult cohort (TASOAC) study

C Ding, V Parameswaran, F Cicuttini, J Burgess, G Zhai, S Quinn, and G Jones

Ann Rheum Dis 2008; 67: 1256-1261.
Published Online First: 3 January 2008. doi:10.1136/ard.2007.082651

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Corticosteroid injections effective for trigger finger in adults in general practice: a double-blinded randomised placebo controlled trial

C Peters-Veluthamaningal, J C Winters, K H Groenier, and B Meyboom-de Jong

Ann Rheum Dis 2008; 67: 1262-1266.
Published Online First: 7 January 2008. doi:10.1136/ard.2007.073106

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Level of radiographic damage and radiographic progression are determinants of physical function: a longitudinal analysis of the TEMPO trial

D van der Heijde, R Landewé, R van Vollenhoven, S Fatenejad, and L Klareskog

Ann Rheum Dis 2008; 67: 1267-1270.
Published Online First: 18 January 2008. doi:10.1136/ard.2007.081331

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Clinical features and risk factors of postsurgical gout

E H Kang, E Y Lee, Y J Lee, Y W Song, and E B Lee

Ann Rheum Dis 2008; 67: 1271-1275.
Published Online First: 12 November 2007. doi:10.1136/ard.2007.078683

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MRI in predicting a major clinical response to anti-tumour necrosis factor treatment in ankylosing spondylitis

M Rudwaleit, S Schwarzlose, E S Hilgert, J Listing, J Braun, and J Sieper

Ann Rheum Dis 2008; 67: 1276-1281.
Published Online First: 15 November 2007. doi:10.1136/ard.2007.073098

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Prevalence and clinical associations of anti-Ku antibodies in patients with systemic sclerosis: a European EUSTAR-initiated multi-centre case–control study

B Rozman, S Cucnik, S Sodin-Semrl, L Czirják, C Varjú, O Distler, D Huscher, M Aringer, G Steiner, M Matucci-Cerinic, S Guiducci, B Stamenkovic, A Stankovic, and T Kveder

Ann Rheum Dis 2008; 67: 1282-1286.
Published Online First: 6 December 2007. doi:10.1136/ard.2007.073981

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The FCRL3 –169T>C polymorphism is associated with rheumatoid arthritis and shows suggestive evidence of involvement with juvenile idiopathic arthritis in a Scandinavian panel of autoimmune diseases

M C Eike, G B N Nordang, T H Karlsen, K M Boberg, M H Vatn on behalf of the IBSEN study group, K Dahl-Jørgensen, K S Rønningen, G Joner, B Flatø, A Bergquist, E Thorsby, Ø Førre, T K Kvien, D E Undlien, and B A Lie

Ann Rheum Dis 2008; 67: 1287-1291.
Published Online First: 7 December 2007. doi:10.1136/ard.2007.077826

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Clinical and functional characterisation of a novel TNFRSF1A c.605T>A/V173D cleavage site mutation associated with tumour necrosis factor receptor-associated periodic fever syndrome (TRAPS), cardiovascular complications and excellent response to etanercept treatment

S Stojanov, C Dejaco, P Lohse, K Huss, C Duftner, B H Belohradsky, M Herold, and M Schirmer

Ann Rheum Dis 2008; 67: 1292-1298.
Published Online First: 7 January 2008. doi:10.1136/ard.2007.079376

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Th1 but not Th17 cells predominate in the joints of patients with rheumatoid arthritis

H Yamada, Y Nakashima, K Okazaki, T Mawatari, J-I Fukushi, N Kaibara, A Hori, Y Iwamoto, and Y Yoshikai

Ann Rheum Dis 2008; 67: 1299-1304.
Published Online First: 6 December 2007. doi:10.1136/ard.2007.080341

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Prospective meta-analysis of interleukin 1 gene complex polymorphisms confirms associations with ankylosing spondylitis

A-M Sims, A E Timms, J Bruges-Armas, R Burgos-Vargas, C-T Chou, T Doan, A Dowling, R N Fialho, P Gergely, D D Gladman, R Inman, M Kauppi, K Kaarela, K Laiho, W Maksymowych, J J Pointon, P Rahman, J D Reveille, R Sorrentino, J Tuomilehto, G Vargas-Alarcon, B P Wordsworth, H Xu, M A Brown, and on behalf of the International Genetics of Ankylosing Spondylitis

Ann Rheum Dis 2008; 67: 1305-1309.
Published Online First: 6 December 2007. doi:10.1136/ard.2007.081364

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Gout is associated with more comorbidities, poorer health-related quality of life and higher healthcare utilisation in US veterans

J A Singh and V Strand

Ann Rheum Dis 2008; 67: 1310-1316.
Published Online First: 4 January 2008. doi:10.1136/ard.2007.081604

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Oesophageal dilatation on high-resolution computed tomography scan of the lungs as a sign of scleroderma

M C Vonk, C E van Die, M M Snoeren, K J Bhansing, P L C M van Riel, J Fransen, and F H J van den Hoogen

Ann Rheum Dis 2008; 67: 1317-1321.
Published Online First: 28 December 2007. doi:10.1136/ard.2007.081612

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Long-term follow-up of relapsing/refractory anti-neutrophil cytoplasm antibody associated vasculitis treated with the lymphocyte depleting antibody alemtuzumab (CAMPATH-1H)

M Walsh, A Chaudhry, and D Jayne

Ann Rheum Dis 2008; 67: 1322-1327.
Published Online First: 29 November 2007. doi:10.1136/ard.2007.081661

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The Mal/TIRAP S180L and TLR4 G299D polymorphisms are not associated with susceptibility to, or severity of, rheumatoid arthritis

F J Sheedy, I Marinou, L A J O’Neill, and A G Wilson

Ann Rheum Dis 2008; 67: 1328-1331.
Published Online First: 7 January 2008. doi:10.1136/ard.2007.083337

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Early and long-lasting protection from arthritis in tumour necrosis factor (TNF) transgenic mice vaccinated against TNF

L Delavallée, H Le Buanec, N Bessis, E Assier, A Denys, B Bizzini, D Zagury, and M-C Boissier

Ann Rheum Dis 2008; 67: 1332-1338.
Published Online First: 27 November 2007. doi:10.1136/ard.2007.079137

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Concise reports:

Effect of intra-articular infliximab on synovial membrane pathology in a patient with a seronegative spondyloarthropathy

M J Ahern, D G Campbell, H Weedon, V Papangelis, and M D Smith

Ann Rheum Dis 2008; 67: 1339-1342.
Published Online First: 13 April 2008. doi:10.1136/ard.2008.090910

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Infliximab efficacy and safety against refractory systemic necrotising vasculitides: long-term follow-up of 15 patients

L Josselin, A Mahr, P Cohen, C Pagnoux, G Guaydier-Souquières, G Hayem, C Job-Deslandre, F Liferman, J Pourrat, and L Guillevin

Ann Rheum Dis 2008; 67: 1343-1346.
Published Online First: 29 April 2008. doi:10.1136/ard.2007.083584

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The role of the shared epitope in arthralgia with anti-cyclic citrullinated peptide antibodies (anti-CCP), and its effect on anti-CCP levels

W H Bos, J Ursum, N de Vries, G M Bartelds, G J Wolbink, M T Nurmohamed, I E van der Horst-Bruinsma, R J van de Stadt, J B A Crusius, P P Tak, B A C Dijkmans, and D van Schaardenburg

Ann Rheum Dis 2008; 67: 1347-1350.
Published Online First: 3 April 2008. doi:10.1136/ard.2008.089953

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Letters:

Extremity magnetic resonance imaging assessment of synovitis (without contrast) in rheumatoid arthritis may be less accurate than power Doppler ultrasound

J E Freeston, A K Brown, E M A Hensor, P Emery, and P G Conaghan

Ann Rheum Dis 2008; 67: 1351. doi:10.1136/ard.2007.082743

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Efficacy of rituximab in Felty’s syndrome

V Lekharaju and C Chattopadhyay

Ann Rheum Dis 2008; 67: 1352. doi:10.1136/ard.2007.078915

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GDF5 Polymorphism associated with osteoarthritis: risk for rheumatoid arthritis

A Martínez, J Varadé, J R Lamas, M Fernández-Arquero, J A Jover, E G de la Concha, B Fernández-Gutiérrez, and E Urcelay

Ann Rheum Dis 2008; 67: 1352-1353. doi:10.1136/ard.2007.085050

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Could tumour necrosis factor blockers inhibit the progression of future structural damage in ankylosing spondylitis?

N Gaspersic, I Sersa, V Jevtic, M Tomsic, and S Praprotnik

Ann Rheum Dis 2008; 67: 1354. doi:10.1136/ard.2007.082537

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Anti-collagen type II antibodies in patients with very early synovitis

K Raza, M Mullazehi, M Salmon, C D Buckley, and J Rönnelid

Ann Rheum Dis 2008; 67: 1354-1355. doi:10.1136/ard.2007.084277

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PostScript:

Trials in rheumatoid arthritis: choosing the right outcome measures—comment on the article by Felson et al

D Porter

Ann Rheum Dis 2008; 67: 1356. doi:10.1136/ard.2008.094805

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CORRECTION

Ann Rheum Dis 2008; 67: 1356.

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