Editorials:

When patients with rheumatoid arthritis fail tumour necrosis factor inhibitors: what is the next step?

Josef S Smolen and Michael E Weinblatt

Ann Rheum Dis 2008; 67: 1497-1498. doi:10.1136/ard.2008.098111

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Reviews:

The metastasis associated protein S100A4: a potential novel link to inflammation and consequent aggressive behaviour of rheumatoid arthritis synovial fibroblasts

L Oslejsková, M Grigorian, S Gay, M Neidhart, and L Senolt

Ann Rheum Dis 2008; 67: 1499-1504.
Published Online First: 4 December 2007. doi:10.1136/ard.2007.079905

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Utility of animal models for identification of potential therapeutics for rheumatoid arthritis

M Hegen, J C Keith, Jr, M Collins, and C L Nickerson-Nutter

Ann Rheum Dis 2008; 67: 1505-1515.
Published Online First: 29 November 2007. doi:10.1136/ard.2007.076430

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Letters:

Duration of pre-rheumatoid arthritis anti-cyclic citrullinated peptide positivity is positively associated with age at seroconversion

W H Bos, M M J Nielen, B A C Dijkmans, and D van Schaardenburg

Ann Rheum Dis 2008; 67: 1642. doi:10.1136/ard.2007.085456

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Anti-thrombopoietin antibodies suppress megakaryocytic colony formation in vitro in patients with systemic lupus erythaematosus

P D Ziakas, H A Papadaki, M Psyllaki, and M Voulgarelis

Ann Rheum Dis 2008; 67: 1643-1644. doi:10.1136/ard.2007.087478

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Anti-tumour necrosis factor therapy modulates ghrelin in patients with severe rheumatoid arthritis

M A Gonzalez-Gay, M T Garcia-Unzueta, A Berja, T R Vazquez-Rodriguez, C Gonzalez-Juanatey, J M de Matias, J Martin, P H Dessein, and J Llorca

Ann Rheum Dis 2008; 67: 1644-1646. doi:10.1136/ard.2008.088773

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Angiotensin receptor blockers reduce erythrocyte sedimentation rate levels in patients with rheumatoid arthritis

M E Perry, M M Chee, W R Ferrell, J C Lockhart, and R D Sturrock

Ann Rheum Dis 2008; 67: 1646-1647. doi:10.1136/ard.2007.082917

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Successful treatment of psoriatic arthritis with rituximab

J D Cohen

Ann Rheum Dis 2008; 67: 1647-1648. doi:10.1136/ard.2007.085290

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Clinical outcome and B cell depletion in patients with rheumatoid arthritis receiving rituximab monotherapy in comparison with patients receiving concomitant methotrexate

K Owczarczyk, M Hellmann, G Fliedner, T Röhrs, K Maizus, D Passon, M Hallek, and A Rubbert

Ann Rheum Dis 2008; 67: 1648-1649. doi:10.1136/ard.2007.087023

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Life-table analysis of etanercept with or without methotrexate in patients with psoriatic arthritis

A Spadaro, F Ceccarelli, R Scrivo, and G Valesini

Ann Rheum Dis 2008; 67: 1650-1651. doi:10.1136/ard.2007.085951

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Corrections:

Correction

Ann Rheum Dis 2008; 67: 1652.

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Correction

Ann Rheum Dis 2008; 67: 1652.

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Basic and translational research:

Imatinib mesylate inhibits in vitro and ex vivo biological responses related to vascular occlusion in giant cell arteritis

E Lozano, M Segarra, A García-Martínez, J Hernández-Rodríguez, and M C Cid

Ann Rheum Dis 2008; 67: 1581-1588.
Published Online First: 21 June 2007. doi:10.1136/ard.2007.070805

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A novel TNFRSF1A splice mutation associated with increased nuclear factor appaB (NF-B) transcription factor activation in patients with tumour necrosis factor receptor associated periodic syndrome (TRAPS)

S M Churchman, L D Church, S Savic, L R Coulthard, B Hayward, B Nedjai, M D Turner, R J Mathews, E Baguley, G A Hitman, H C Gooi, P M D Wood, P Emery, and M F McDermott

Ann Rheum Dis 2008; 67: 1589-1595.
Published Online First: 17 December 2007. doi:10.1136/ard.2007.078667

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Effects of immunosuppressive treatment on microsomal prostaglandin E synthase 1 and cyclooxygenases expression in muscle tissue of patients with polymyositis or dermatomyositis

M Korotkova, S Barbasso Helmers, I Loell, H Alexanderson, C Grundtman, C Dorph, I E Lundberg, and P-J Jakobsson

Ann Rheum Dis 2008; 67: 1596-1602.
Published Online First: 18 December 2007. doi:10.1136/ard.2007.079525

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CTLA-4 directly inhibits osteoclast formation

R Axmann, S Herman, M Zaiss, S Franz, K Polzer, J Zwerina, M Herrmann, J Smolen, and G Schett

Ann Rheum Dis 2008; 67: 1603-1609.
Published Online First: 18 January 2008. doi:10.1136/ard.2007.080713

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Tumour necrosis factor blockade increases lymphangiogenesis in murine and human arthritic joints

K Polzer, D Baeten, A Soleiman, J Distler, D M Gerlag, P P Tak, G Schett, and J Zwerina

Ann Rheum Dis 2008; 67: 1610-1616.
Published Online First: 3 January 2008. doi:10.1136/ard.2007.083394

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Annexin 5 overexpression increased articular chondrocyte apoptosis induced by basic calcium phosphate crystals

H K Ea, V Monceau, E Camors, M Cohen-Solal, D Charlemagne, and F Lioté

Ann Rheum Dis 2008; 67: 1617-1625.
Published Online First: 24 January 2008. doi:10.1136/ard.2008.087718

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IgG autoantibodies bound to surfaces of necrotic cells and complement C4 comprise the phagocytosis promoting activity for necrotic cells of systemic lupus erythaematosus sera

G E Grossmayer, L E Munoz, C K Weber, S Franz, R E Voll, P M Kern, J R Kalden, G Schett, M Herrmann, and U S Gaipl

Ann Rheum Dis 2008; 67: 1626-1632.
Published Online First: 28 December 2007. doi:10.1136/ard.2007.081828

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Differential Toll-like receptor-dependent collagenase expression in chondrocytes

Q Zhang, W Hui, G J Litherland, M J Barter, R Davidson, C Darrah, S T Donell, I M Clark, T E Cawston, J H Robinson, A D Rowan, and D A Young

Ann Rheum Dis 2008; 67: 1633-1641.
Published Online First: 7 February 2008. doi:10.1136/ard.2007.079574

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Clinical and epidemiological research:

IL-6 receptor inhibition with tocilizumab improves treatment outcomes in patients with rheumatoid arthritis refractory to anti-tumour necrosis factor biologicals: results from a 24-week multicentre randomised placebo-controlled trial

P Emery, E Keystone, H P Tony, A Cantagrel, R van Vollenhoven, A Sanchez, E Alecock, J Lee, and J Kremer

Ann Rheum Dis 2008; 67: 1516-1523.
Published Online First: 14 July 2008. doi:10.1136/ard.2008.092932

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Knee alignment differences between Chinese and Caucasian subjects without osteoarthritis

W F Harvey, J Niu, Y Zhang, P I McCree, D T Felson, M Nevitt, L Xu, P Aliabadi, and D J Hunter

Ann Rheum Dis 2008; 67: 1524-1528.
Published Online First: 29 January 2008. doi:10.1136/ard.2007.074294

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Cigarette smoking, disease severity and autoantibody expression in African Americans with recent-onset rheumatoid arthritis

T R Mikuls, L B Hughes, A O Westfall, V M Holers, L Parrish, D van der Heijde, M van Everdingen, G S Alarcón, D L Conn, B Jonas, L F Callahan, E A Smith, G Gilkeson, G Howard, L W Moreland, and S L Bridges, Jr

Ann Rheum Dis 2008; 67: 1529-1534.
Published Online First: 15 January 2008. doi:10.1136/ard.2007.082669

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The diagnostic value of scintigraphy in assessing sacroiliitis in ankylosing spondylitis: a systematic literature research

I H Song, J Carrasco-Fernández, M Rudwaleit, and J Sieper

Ann Rheum Dis 2008; 67: 1535-1540.
Published Online First: 29 January 2008. doi:10.1136/ard.2007.083089

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Reduction of fatigue in Sjögren syndrome with rituximab: results of a randomised, double-blind, placebo-controlled pilot study

S Dass, S J Bowman, E M Vital, K Ikeda, C T Pease, J Hamburger, A Richards, S Rauz, and P Emery

Ann Rheum Dis 2008; 67: 1541-1544.
Published Online First: 14 February 2008. doi:10.1136/ard.2007.083865

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Premorbid knee osteoarthritis is not characterised by diffuse thinness: the Framingham Osteoarthritis Study

D J Hunter, J B Niu, Y Zhang, M LaValley, C E McLennan, M Hudelmaier, F Eckstein, and D T Felson

Ann Rheum Dis 2008; 67: 1545-1549.
Published Online First: 24 January 2008. doi:10.1136/ard.2007.076810

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Lymphotoxin 252A>G polymorphism is common and associates with myocardial infarction in patients with rheumatoid arthritis

V F Panoulas, S N Nikas, J P Smith, K M J Douglas, P Nightingale, H J Milionis, G J Treharne, T E Toms, M D Kita, and G D Kitas

Ann Rheum Dis 2008; 67: 1550-1556.
Published Online First: 29 January 2008. doi:10.1136/ard.2007.082594

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Anti-cyclic citrullinated peptide revised criteria for the classification of rheumatoid arthritis

K P Liao, K L Batra, L Chibnik, P H Schur, and K H Costenbader

Ann Rheum Dis 2008; 67: 1557-1561.
Published Online First: 30 January 2008. doi:10.1136/ard.2007.082339

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Head-to-head comparison of the Lyon Schuss and fixed flexion radiographic techniques. Long-term reproducibility in normal knees and sensitivity to change in osteoarthritic knees

M-P Hellio Le Graverand, E P Vignon, K D Brandt, S A Mazzuca, M Piperno, R Buck, H C Charles, D J Hunter, C G Jackson, V Byers Kraus, T M Link, T J Schnitzer, A Vaz, and B Wyman

Ann Rheum Dis 2008; 67: 1562-1566.
Published Online First: 7 February 2008. doi:10.1136/ard.2007.077834

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Anti-tumour necrosis factor therapy in patients with refractory Takayasu arteritis: long-term follow-up

E S Molloy, C A Langford, T M Clark, C E Gota, and G S Hoffman

Ann Rheum Dis 2008; 67: 1567-1569.
Published Online First: 3 August 2008. doi:10.1136/ard.2008.093260

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Vitamin K in hand osteoarthritis: results from a randomised clinical trial

T Neogi, D T Felson, R Sarno, and S L Booth

Ann Rheum Dis 2008; 67: 1570-1573.
Published Online First: 14 July 2008. doi:10.1136/ard.2008.094771

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Tight control and intensified COBRA combination treatment in early rheumatoid arthritis: 90% remission in a pilot trial

L H D van Tuyl, W F Lems, A E Voskuyl, P J S M Kerstens, P Garnero, B A C Dijkmans, and M Boers

Ann Rheum Dis 2008; 67: 1574-1577.
Published Online First: 14 July 2008. doi:10.1136/ard.2008.090712

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The TRAF1/C5 region is a risk factor for polyarthritis in juvenile idiopathic arthritis

H M Albers, F A S Kurreeman, J J Houwing-Duistermaat, D M C Brinkman, S S M Kamphuis, H J Girschick, C Wouters, M A J Van Rossum, W Verduijn, R E M Toes, T W J Huizinga, M W Schilham, and R ten Cate

Ann Rheum Dis 2008; 67: 1578-1580.
Published Online First: 1 July 2008. doi:10.1136/ard.2008.089060

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