Editorials:

What does the clinician need to improve patient care in systemic sclerosis?

Madelon C Vonk, Frank H J van den Hoogen, Piet L C M van Riel, and Gabriele Valentini

Ann Rheum Dis 2007; 66: 1129-1131. doi:10.1136/ard.2007.073957

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Reviews:

What effects might anti-TNF treatment be expected to have on cardiovascular morbidity and mortality in rheumatoid arthritis? A review of the role of TNF in cardiovascular pathophysiology

W G Dixon and D P M Symmons

Ann Rheum Dis 2007; 66: 1132-1136.
Published Online First: 24 January 2007. doi:10.1136/ard.2006.063867

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Vitamin D and autoimmunity: new aetiological and therapeutic considerations

Yoav Arnson, Howard Amital, and Yehuda Shoenfeld

Ann Rheum Dis 2007; 66: 1137-1142.
Published Online First: 8 June 2007. doi:10.1136/ard.2007.069831

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Extended reports:

Reduction of arthritis following intra-articular administration of an adeno-associated virus serotype 5 expressing a disease-inducible TNF-blocking agent

J Adriaansen, M Khoury, C J de Cortie, F J Fallaux, P Bigey, D Scherman, D J Gould, Y Chernajovsky, F Apparailly, C Jorgensen, M J B M Vervoordeldonk, and P P Tak

Ann Rheum Dis 2007; 66: 1143-1150.
Published Online First: 15 March 2007. doi:10.1136/ard.2006.064519

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Imbalance in distribution of functional autologous regulatory T cells in rheumatoid arthritis

Frank Behrens, Andrea Himsel, Stefan Rehart, Joanna Stanczyk, Björn Beutel, Stefanie Y Zimmermann, Ulrike Koehl, Burkhard Möller, Steffen Gay, Joachim P Kaltwasser, Josef M Pfeilschifter, and Heinfried H Radeke

Ann Rheum Dis 2007; 66: 1151-1156.
Published Online First: 28 March 2007. doi:10.1136/ard.2006.068320

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Research in hand osteoarthritis: time for reappraisal and demand for new strategies. An opinion paper

Margreet Kloppenburg, Tanja Stamm, Iain Watt, Franz Kainberger, Tim E Cawston, Fraser N Birrell, Ingemar F Petersson, Tore Saxne, Tore K Kvien, Barbara Slatkowsky-Christensen, Maxime Dougados, Laure Gossec, Ferdinand C Breedveld, and Josef S Smolen

Ann Rheum Dis 2007; 66: 1157-1161.
Published Online First: 14 March 2007. doi:10.1136/ard.2007.070813

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Study of active controlled monotherapy used for rheumatoid arthritis, an IL-6 inhibitor (SAMURAI): evidence of clinical and radiographic benefit from an x ray reader-blinded randomised controlled trial of tocilizumab

Norihiro Nishimoto, Jun Hashimoto, Nobuyuki Miyasaka, Kazuhiko Yamamoto, Shinichi Kawai, Tsutomu Takeuchi, Norikazu Murata, Désirée van der Heijde, and Tadamitsu Kishimoto

Ann Rheum Dis 2007; 66: 1162-1167.
Published Online First: 7 May 2007. doi:10.1136/ard.2006.068064

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Effect of hydroxychloroquine on the survival of patients with systemic lupus erythematosus: data from LUMINA, a multiethnic US cohort (LUMINA L)

Graciela S Alarcón, Gerald McGwin, Ana M Bertoli, Barri J Fessler, Jaime Calvo-Alén, Holly M Bastian, Luis M Vilá, John D Reveille for the LUMINA Study Group

Ann Rheum Dis 2007; 66: 1168-1172.
Published Online First: 27 March 2007. doi:10.1136/ard.2006.068676

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Development of additional autoimmune diseases in a multiethnic cohort of patients with systemic lupus erythematosus with reference to damage and mortality

S A Chambers, S C Charman, A Rahman, and D A Isenberg

Ann Rheum Dis 2007; 66: 1173-1177.
Published Online First: 9 January 2007. doi:10.1136/ard.2006.062984

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Efficacy and safety of epicutaneous ketoprofen in Transfersome (IDEA-033) versus oral celecoxib and placebo in osteoarthritis of the knee: multicentre randomised controlled trial

Matthias Rother, Bernard J Lavins, Werner Kneer, Klaus Lehnhardt, Egbert J Seidel, and Stefan Mazgareanu

Ann Rheum Dis 2007; 66: 1178-1183.
Published Online First: 15 March 2007. doi:10.1136/ard.2006.065128

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Do rheumatoid arthritis patients in clinical practice benefit from switching from infliximab to a second tumor necrosis factor alpha inhibitor?

Elisabeth Hjardem, Mikkel Østergaard, Jan Pødenphant, Ulrik Tarp, Lis Smedegaard Andersen, Jette Bing, Elisabeth Peen, Hanne Merete Lindegaard, Vibeke Stevenius Ringsdal, Anne Rødgaard, Jens Skøt, Annette Hansen, Hans Henrik Mogensen, Janne Unkerskov, and Merete Lund Hetland

Ann Rheum Dis 2007; 66: 1184-1189.
Published Online First: 27 March 2007. doi:10.1136/ard.2006.054742

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Does knee pain in the community behave like a regional pain syndrome? Prospective cohort study of incidence and persistence

K T Palmer, I Reading, M Calnan, C Linaker, and D Coggon

Ann Rheum Dis 2007; 66: 1190-1194.
Published Online First: 17 November 2006. doi:10.1136/ard.2006.061481

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Pain and psychological health status over a 10-year period in patients with recent onset rheumatoid arthritis

Sigrid Ødegård, Arnstein Finset, Petter Mowinckel, Tore K. Kvien, and Till Uhlig

Ann Rheum Dis 2007; 66: 1195-1201.
Published Online First: 28 March 2007. doi:10.1136/ard.2006.064287

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Radical oxygen species production induced by advanced oxidation protein products predicts clinical evolution and response to treatment in systemic sclerosis

A Servettaz, P Guilpain, C Goulvestre, C Chéreau, C Hercend, C Nicco, L Guillevin, B Weill, L Mouthon, and F Batteux

Ann Rheum Dis 2007; 66: 1202-1209.
Published Online First: 15 March 2007. doi:10.1136/ard.2006.067504

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Polymorphism of immunoglobulin enhancer element HS1,2A: allele *2 associates with systemic sclerosis. Comparison with HLA-DR and DQ allele frequency

D Frezza, V Giambra, B Tolusso, M De Santis, S Bosello, S Vettori, G Triolo, G Valentini, and G Ferraccioli

Ann Rheum Dis 2007; 66: 1210-1215.
Published Online First: 28 March 2007. doi:10.1136/ard.2006.066597

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Introduction of a novel magnetic resonance imaging tenosynovitis score for rheumatoid arthritis: reliability in a multireader longitudinal study

Espen A Haavardsholm, Mikkel Østergaard, Bo J Ejbjerg, Nils P Kvan, and Tore K Kvien

Ann Rheum Dis 2007; 66: 1216-1220.
Published Online First: 28 March 2007. doi:10.1136/ard.2006.068361

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Disease Activity Score 28 (DAS28) using C-reactive protein underestimates disease activity and overestimates EULAR response criteria compared with DAS28 using erythrocyte sedimentation rate in a large observational cohort of rheumatoid arthritis patients in Japan

Toshihiro Matsui, Yoshiaki Kuga, Atsushi Kaneko, Jinju Nishino, Yoshito Eto, Noriyuki Chiba, Masayuki Yasuda, Koichiro Saisho, Kota Shimada, and Shigeto Tohma

Ann Rheum Dis 2007; 66: 1221-1226.
Published Online First: 16 March 2007. doi:10.1136/ard.2006.063834

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Patient preferences for treatment: report from a randomised comparison of treatment strategies in early rheumatoid arthritis (BeSt trial)

Yvonne P M Goekoop-Ruiterman, Jeska K de Vries-Bouwstra, Cornelia F Allaart, Pit J S M Kerstens, Bernard A M Grillet, Mike H de Jager, K Huub Han, Irene Speyer, Peter A H M van der Lubbe, Patrick E H Seys, Ferdinand C Breedveld, and Ben A C Dijkmans

Ann Rheum Dis 2007; 66: 1227-1232.
Published Online First: 3 April 2007. doi:10.1136/ard.2006.068296

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Double-blinded infliximab dose escalation in patients with rheumatoid arthritis

Mahboob U Rahman, Ingrid Strusberg, Piet Geusens, Alberto Berman, David Yocum, Daniel Baker, Carrie Wagner, John Han, and Rene Westhovens

Ann Rheum Dis 2007; 66: 1233-1238.
Published Online First: 28 March 2007. doi:10.1136/ard.2006.065995

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A pilot study of a Mediterranean-type diet intervention in female patients with rheumatoid arthritis living in areas of social deprivation in Glasgow

G McKellar, E Morrison, A McEntegart, R Hampson, A Tierney, G Mackle, J Scoular, J A Scott, and H A Capell

Ann Rheum Dis 2007; 66: 1239-1243.
Published Online First: 5 July 2007. doi:10.1136/ard.2006.065151

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Body composition and knee cartilage properties in healthy, community-based adults

Yuanyuan Wang, Anita E Wluka, Dallas R English, Andrew J Teichtahl, Graham G Giles, Richard O’Sullivan, and Flavia M Cicuttini

Ann Rheum Dis 2007; 66: 1244-1248.
Published Online First: 29 January 2007. doi:10.1136/ard.2006.064352

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Concise reports:

Contribution of anti-cyclic citrullinated peptide antibody and rheumatoid factor to the diagnosis of arthropathy in haemochromatosis

E Aigner, I Schmid, C H Österreicher, J Zwerina, G Schett, M Strasser, F Niksic, F Hohla, T Ramsauer, U Dorn, W Patsch, and C Datz

Ann Rheum Dis 2007; 66: 1249-1251.
Published Online First: 24 April 2007. doi:10.1136/ard.2007.071621

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Decreased clinical response to infliximab in ankylosing spondylitis is correlated with anti-infliximab formation

Mirjam K de Vries, Gerrit Jan Wolbink, Steven O Stapel, Henk de Vrieze, J Christiaan van Denderen, Ben A C Dijkmans, Lucien A Aarden, and Irene E van der Horst-Bruinsma

Ann Rheum Dis 2007; 66: 1252-1254.
Published Online First: 1 May 2007. doi:10.1136/ard.2007.072397

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Optic neuritis occurring with anti-tumour necrosis factor therapy

Ismail Simsek, Hakan Erdem, Salih Pay, Gungor Sobaci, and Ayhan Dinc

Ann Rheum Dis 2007; 66: 1255-1258.
Published Online First: 24 April 2007. doi:10.1136/ard.2006.066787

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B cell depletion therapy in systemic lupus erythematosus: long-term follow-up and predictors of response

Kristine P Ng, Geraldine Cambridge, Maria J Leandro, Jonathan C W Edwards, Michael Ehrenstein, and David A Isenberg

Ann Rheum Dis 2007; 66: 1259-1262.
Published Online First: 5 April 2007. doi:10.1136/ard.2006.067124

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Letters:

Protective effect of A at position –168 in the type III promoter of the MHCIITA gene in systemic lupus erythematosus

Hiroshi Okamoto, Hirotaka Kaneko, Chihiro Terai, and Naoyuki Kamatani

Ann Rheum Dis 2007; 66: 1263-1264. doi:10.1136/ard.2006.066142

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Crico-thyroid perichondritis leading to sore throat in patients with active adult-onset Still’s disease

Der-Yuan Chen, Howard Haw-Chang Lan, Tsu-Yi Hsieh, Hsin-Hua Chen, and Joung-Liang Lan

Ann Rheum Dis 2007; 66: 1264-1266. doi:10.1136/ard.2006.065342

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The low-penetrance R92Q mutation of the tumour necrosis factor superfamily 1A gene is neither a major risk factor for Wegener’s granulomatosis nor multiple sclerosis

Dieter E Jenne, Peer M Aries, Simon Einwächter, Amer D Akkad, Stefan Wieczorek, Peter Lamprecht, and Wolfgang L Gross

Ann Rheum Dis 2007; 66: 1266-1267. doi:10.1136/ard.2006.065987

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Serum serotonin levels are not useful in diagnosing fibromyalgia

Gabriel Jaschko, Urs Hepp, Magdalena Berkhoff, Margrit Schmet, Beat A Michel, Steffen Gay, and Haiko Sprott

Ann Rheum Dis 2007; 66: 1267-1268. doi:10.1136/ard.2006.058842

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