Editorials:

Is there a microangiopathic antiphospholipid syndrome?

Ronald A Asherson, Sylvia S Pierangeli, and Ricard Cervera

Ann Rheum Dis 2007; 66: 429-432. doi:10.1136/ard.2006.067033

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Reviews:

Effect of weight reduction in obese patients diagnosed with knee osteoarthritis: a systematic review and meta-analysis

Robin Christensen, Else Marie Bartels, Arne Astrup, and Henning Bliddal

Ann Rheum Dis 2007; 66: 433-439.
Published Online First: 4 January 2007. doi:10.1136/ard.2006.065904

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Management of septic arthritis: a systematic review

C J Mathews, G Kingsley, M Field, A Jones, V C Weston, M Phillips, D Walker, and G Coakley

Ann Rheum Dis 2007; 66: 440-445.
Published Online First: 12 January 2007. doi:10.1136/ard.2006.058909

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Extended reports:

Attachment to laminin-111 facilitates transforming growth factor ß-induced expression of matrix metalloproteinase-3 in synovial fibroblasts

Maik Hoberg, Maximilian Rudert, Thomas Pap, Gerd Klein, Steffen Gay, and Wilhelm K Aicher

Ann Rheum Dis 2007; 66: 446-451.
Published Online First: 23 November 2006. doi:10.1136/ard.2006.060228

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GM-CSF neutralisation suppresses inflammation and protects cartilage in acute streptococcal cell wall arthritis of mice

C Plater-Zyberk, L A B Joosten, M M A Helsen, J Hepp, P A Baeuerle, and W B van den Berg

Ann Rheum Dis 2007; 66: 452-457.
Published Online First: 4 October 2006. doi:10.1136/ard.2006.057182

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Resistin in rheumatoid arthritis synovial tissue, synovial fluid and serum

L Senolt, D Housa, Z Vernerová, T Jirásek, R Svobodová, D Veigl, K Anderlová, U Müller-Ladner, K Pavelka, and M Haluzík

Ann Rheum Dis 2007; 66: 458-463.
Published Online First: 13 October 2006. doi:10.1136/ard.2006.054734

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Reproducibility and sensitivity to change of four scoring methods for the radiological assessment of osteoarthritis of the hand

Emmanuel Maheu, Christian Cadet, Sylvie Gueneugues, Philippe Ravaud, and Maxime Dougados

Ann Rheum Dis 2007; 66: 464-469.
Published Online First: 15 November 2006. doi:10.1136/ard.2006.060277

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Efficacy of rituximab (anti-CD20) for refractory systemic lupus erythematosus involving the central nervous system

Mikiko Tokunaga, Kazuyoshi Saito, Daisuke Kawabata, Yoshitaka Imura, Takao Fujii, Shingo Nakayamada, Shizuyo Tsujimura, Masao Nawata, Shigeru Iwata, Taeko Azuma, Tsuneyo Mimori, and Yoshiya Tanaka

Ann Rheum Dis 2007; 66: 470-475.
Published Online First: 15 November 2006. doi:10.1136/ard.2006.057885

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Reduced telomere length in rheumatoid arthritis is independent of disease activity and duration

Sophia E Steer, Frances M K Williams, Bernet Kato, Jeffry P Gardner, Paul J Norman, Margaret A Hall, Masayuki Kimura, Robert Vaughan, Abraham Aviv, and Tim D Spector

Ann Rheum Dis 2007; 66: 476-480.
Published Online First: 17 November 2006. doi:10.1136/ard.2006.059188

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Sulphasalazine inhibits human antigen-specific immune responses in vivo

Christina Trollmo, Sveinn Gudmundsson, Nils Feltelius, Siv Rogberg, Göran Smedegård, and Lars Klareskog

Ann Rheum Dis 2007; 66: 481-485.
Published Online First: 19 September 2006. doi:10.1136/ard.2006.059881

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Early functional disability predicts both all-cause and cardiovascular mortality in people with inflammatory polyarthritis: results from the Norfolk Arthritis Register

Tracey M Farragher, Mark Lunt, Diane K Bunn, Alan J Silman, and Deborah P M Symmons

Ann Rheum Dis 2007; 66: 486-492.
Published Online First: 7 November 2006. doi:10.1136/ard.2006.056390

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Prediction of major clinical response (ACR50) to infliximab in psoriatic arthritis refractory to methotrexate

J Gratacós, E Casado, J Real, and J C Torre-Alonso

Ann Rheum Dis 2007; 66: 493-497.
Published Online First: 19 December 2006. doi:10.1136/ard.2006.060079

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Infliximab maintains a high degree of clinical response in patients with active psoriatic arthritis through 1 year of treatment: results from the IMPACT 2 trial

A Kavanaugh, G G Krueger, A Beutler, C Guzzo, B Zhou, L T Dooley, P J Mease, D D Gladman, K de Vlam, P P Geusens, C Birbara, D G Halter, C Antoni for the IMPACT 2 Study Group

Ann Rheum Dis 2007; 66: 498-505.
Published Online First: 17 November 2006. doi:10.1136/ard.2006.058339

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Cardiac dysfunction in patients with systemic lupus erythematosus and antiphospholipid syndrome

Daphna Paran, Dan Caspi, David Levartovsky, Ori Elkayam, Ilana Kaufman, Irena Litinsky, Gad Keren, and Bella Koifman

Ann Rheum Dis 2007; 66: 506-510.
Published Online First: 1 November 2006. doi:10.1136/ard.2005.044073

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Anti-cyclic citrullinated peptide positivity in non-rheumatoid arthritis disease samples: citrulline-dependent or not?

A Vannini, K Cheung, M Fusconi, J Stammen-Vogelzangs, J P H Drenth, A C Dall’Aglio, F B Bianchi, L E Bakker-Jonges, W J van Venrooij, G J M Pruijn, and A J W Zendman

Ann Rheum Dis 2007; 66: 511-516.
Published Online First: 19 September 2006. doi:10.1136/ard.2006.058933

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Pressure pain thresholds and tender point counts as predictors of new chronic widespread pain in somatising subjects

A Gupta, J McBeth, G J Macfarlane, R Morriss, C Dickens, D Ray, Y H Chiu, and A J Silman

Ann Rheum Dis 2007; 66: 517-521.
Published Online First: 29 September 2006. doi:10.1136/ard.2006.054650

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Diagnostic quality and scoring of synovitis, tenosynovitis and erosions in low-field MRI of patients with rheumatoid arthritis: a comparison with conventional MRI

Claudia Schirmer, Alexander K Scheel, Christian E Althoff, Tania Schink, Iris Eshed, Alexander Lembcke, Gerd-Rüdiger Burmester, Marina Backhaus, Bernd Hamm, and Kay-Geert A Hermann

Ann Rheum Dis 2007; 66: 522-529.
Published Online First: 26 October 2006. doi:10.1136/ard.2006.056366

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Concise reports:

Cell-ELISA detection of antineuronal antibodies in central nervous system involvement in systemic lupus erythematosus

Xuan Zhang, Huijun Shu, Fengchun Zhang, Xinping Tian, and Yi Dong

Ann Rheum Dis 2007; 66: 530-532.
Published Online First: 11 August 2006. doi:10.1136/ard.2006.055772

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Factor XII autoantibodies as a novel marker for thrombosis and adverse obstetric history in patients with systemic lupus erythematosus

Maria Laura Bertolaccini, Kirti Mepani, Giovanni Sanna, Graham R V Hughes, and Munther A Khamashta

Ann Rheum Dis 2007; 66: 533-536.
Published Online First: 4 October 2006. doi:10.1136/ard.2006.059022

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High anti-collagen type-II antibody levels and induction of proinflammatory cytokines by anti-collagen antibody-containing immune complexes in vitro characterise a distinct rheumatoid arthritis phenotype associated with acute inflammation at the time of disease onset

Mohammed Mullazehi, Linda Mathsson, Jon Lampa, and Johan Rönnelid

Ann Rheum Dis 2007; 66: 537-541.
Published Online First: 13 October 2006. doi:10.1136/ard.2006.064782

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Formative research in clinical trial development: attitudes of patients with arthritis in enhancing prevention trials

Holly A Taylor, Jeremy Sugarman, David S Pisetsky, and Joan Bathon

Ann Rheum Dis 2007; 66: 542-544.
Published Online First: 19 September 2006. doi:10.1136/ard.2006.059600

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Real-time quantitative PCR to detect changes in synovial gene expression in rheumatoid arthritis after corticosteroid treatment

Danielle M Gerlag, David L Boyle, Sanna Rosengren, Tony Nash, Paul P Tak, and Gary S Firestein

Ann Rheum Dis 2007; 66: 545-547.
Published Online First: 19 September 2006. doi:10.1136/ard.2006.059790

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Infliximab and etanercept in the treatment of chronic uveitis associated with refractory juvenile idiopathic arthritis

Pirjo Tynjälä, Päivi Lindahl, Visa Honkanen, Pekka Lahdenne, and Kaisu Kotaniemi

Ann Rheum Dis 2007; 66: 548-550.
Published Online First: 26 October 2006. doi:10.1136/ard.2006.058248

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Risk factors for lung cancer in patients with scleroderma: a nested case–control study

Eliza K Pontifex, Catherine L Hill, and Peter Roberts-Thomson

Ann Rheum Dis 2007; 66: 551-553.
Published Online First: 19 September 2006. doi:10.1136/ard.2006.056424

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Vasculitis restricted to the lower limbs: a clinical and histopathological study

M Khellaf, M Hamidou, C Pagnoux, M Michel, J M Brisseau, X Chevallier, P Cohen, L Guillevin, and B Godeau

Ann Rheum Dis 2007; 66: 554-556.
Published Online First: 26 October 2006. doi:10.1136/ard.2006.065110

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Letters:

Will steroidal aromatase inhibitors induce rheumatoid arthritis?

Benoit Morel, Hubert Marotte, and Pierre Miossec

Ann Rheum Dis 2007; 66: 557-558. doi:10.1136/ard.2006.066159

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Improved insulin sensitivity by anti-TNF antibody treatment in patients with rheumatic diseases

Frank C Huvers, Calin Popa, Mihai G Netea, Frank H J van den Hoogen, and Cees J Tack

Ann Rheum Dis 2007; 66: 558-559. doi:10.1136/ard.2006.062323

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Study of DNASE I gene polymorphisms in systemic lupus erythematosus susceptibility

Ana Bodaño, Antonio González, Eva Balada, Josep Ordi, Patricia Carreira, Juan J Gómez-Reino, and Carmen Conde

Ann Rheum Dis 2007; 66: 560-561. doi:10.1136/ard.2006.067140

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High disease activity of ankylosing spondylitis in the community before the introduction of tumour necrosis factor blockers

Josef Hermann, Thomas Müller, Babak Yazdani-Biuki, Martin Aringer, Manfred Herold, Wolfgang Ebner, Petra Ofner, and Winfried Graninger

Ann Rheum Dis 2007; 66: 561-562. doi:10.1136/ard.2006.060061

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Association of tumour necrosis factor promoter polymorphisms with ankylosing spondylitis in Taiwan

Ming-Yuh Shiau, Mei-Kuei Lo, Cheng-Pei Chang, Tzi-Peng Yang, Kuo-Ting Ho, and Yih-Hsin Chang

Ann Rheum Dis 2007; 66: 562-563. doi:10.1136/ard.2006.065888

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Infliximab in patients with systemic vasculitis that is difficult to treat: poor outcome and significant adverse effects

Shirish R Sangle, Graham R V Hughes, and David P D’Cruz

Ann Rheum Dis 2007; 66: 564-565. doi:10.1136/ard.2006.065623

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Adalimumab: a new modality for Behçet’s disease?

J A M van Laar, T Missotten, P L A van Daele, A Jamnitski, G S Baarsma, and P M van Hagen

Ann Rheum Dis 2007; 66: 565-566.
Published Online First: 23 November 2006. doi:10.1136/ard.2006.064279

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Autosplenectomy: rare syndrome in autoimmunopathy

J Leipe, A J Hueber, S Kallert, J Rech, and H Schulze-Koops

Ann Rheum Dis 2007; 66: 566-567. doi:10.1136/ard.2006.063313

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