Menu

rss

Online First


Online First articles have been peer reviewed, accepted for publication, published online and indexed by PubMed; they have not yet been assigned to a journal issue. When an article is published in an issue it will be removed from this page.

Online First articles are copy-edited, typeset and approved by the author before publication and we aim to post each article within 3 weeks of acceptance.

Articles appear on this page in reverse chronological order; you may also view by section by clicking on the link at the top of the column to the right.

More about Online First, including how to cite >>

View multiple abstracts by picking relevant boxes and click Get all checked abstracts

Basic and translational research

    Basic and translational research: Concise report: Deletion of LCE3C and LCE3B genes at PSORS4 does not contribute to susceptibility to psoriatic arthritis in German patients
    • Ulrike Hüffmeier,
    • Xavier Estivill,
    • Eva Riveira-Munoz,
    • Heiko Traupe,
    • Jörg Wendler,
    • Jörg Lohmann,
    • Beate Böhm,
    • Harald Burkhardt,
    • André Reis
    Ann Rheum Dis doi:10.1136/ard.2010.108951
    Open Access
    Basic and translational research: Extended Report: A genetic variant in the region of MMP-9 is associated with serum levels and progression of joint damage in rheumatoid arthritis
    • D P C de Rooy,
    • A Zhernakova,
    • R Tsonaka,
    • A Willemze,
    • B A S Kurreeman,
    • G Trynka,
    • L van Toorn,
    • R E M Toes,
    • T W J Huizinga,
    • J J Houwing-Duistermaat,
    • P K Gregersen,
    • A H M van der Helm-van Mil
    Ann Rheum Dis Published Online First: 21 May 2013 doi:10.1136/annrheumdis-2013-203375
    Basic and translational research: Extended Report: Evidence of NLRP3-inflammasome activation in rheumatoid arthritis (RA); genetic variants within the NLRP3-inflammasome complex in relation to susceptibility to RA and response to anti-TNF treatment
    • Rebeccah J Mathews,
    • James I Robinson,
    • Michele Battellino,
    • Chi Wong,
    • John C Taylor,
    • Steve Eyre,
    • Sarah M Churchman,
    • Anthony G Wilson,
    • John D Isaacs,
    • Kimme Hyrich,
    • Anne Barton,
    • Darren Plant,
    • Sinisa Savic,
    • Graham P Cook,
    • Piercarlo Sarzi-Puttini,
    • Paul Emery,
    • Jennifer H Barrett,
    • Ann W Morgan,
    • Michael F McDermott
    Ann Rheum Dis Published Online First: 17 May 2013 doi:10.1136/annrheumdis-2013-203276
    Basic and translational research: Extended Report: Autoantibodies against CD74 in spondyloarthritis
    • N T Baerlecken,
    • S Nothdorft,
    • G H Stummvoll,
    • J Sieper,
    • M Rudwaleit,
    • S Reuter,
    • T Matthias,
    • R E Schmidt,
    • T Witte
    Ann Rheum Dis Published Online First: 17 May 2013 doi:10.1136/annrheumdis-2012-202208
    Basic and translational research: Concise Report: Sclerostin inhibition reverses systemic, periarticular and local bone loss in arthritis
    • Xiao-Xiang Chen,
    • Wolfgang Baum,
    • Denise Dwyer,
    • Michael Stock,
    • Kay Schwabe,
    • Hua-Zhu Ke,
    • Marina Stolina,
    • Georg Schett,
    • Aline Bozec
    Ann Rheum Dis Published Online First: 10 May 2013 doi:10.1136/annrheumdis-2013-203345
    Open Access
    Basic and translational research: Concise Report: Regulatory B cells in ANCA-associated vasculitis
    • B Wilde,
    • M Thewissen,
    • J Damoiseaux,
    • S Knippenberg,
    • M Hilhorst,
    • P van Paassen,
    • O Witzke,
    • J W Cohen Tervaert
    Ann Rheum Dis Published Online First: 10 May 2013 doi:10.1136/annrheumdis-2012-202986
    Basic and translational research: Concise Report: The cellular composition of lymph nodes in the earliest phase of inflammatory arthritis
    • L G M van Baarsen,
    • M J H de Hair,
    • T H Ramwadhdoebe,
    • IJ A J Zijlstra,
    • M Maas,
    • D M Gerlag,
    • P P Tak
    Ann Rheum Dis Published Online First: 9 May 2013 doi:10.1136/annrheumdis-2012-202990
    Open Access
    Basic and translational research: Extended Report: Heat shock protein 90 (Hsp90) inhibition targets canonical TGF-β signalling to prevent fibrosis
    • Michal Tomcik,
    • Pawel Zerr,
    • Jana Pitkowski,
    • Katrin Palumbo-Zerr,
    • Jérôme Avouac,
    • Oliver Distler,
    • Radim Becvar,
    • Ladislav Senolt,
    • Georg Schett,
    • Jörg H Distler
    Ann Rheum Dis Published Online First: 9 May 2013 doi:10.1136/annrheumdis-2012-203095
    Basic and translational research: Extended Report: Hypoxia and hypoxia-inducible factor-1α provoke toll-like receptor signalling-induced inflammation in rheumatoid arthritis
    • Fanlei Hu,
    • Rong Mu,
    • Jiaxin Zhu,
    • Lianjie Shi,
    • Yingni Li,
    • Xu Liu,
    • Wenwei Shao,
    • Guiye Li,
    • Minghui Li,
    • Yin Su,
    • Philip L Cohen,
    • Xiaoyan Qiu,
    • Zhanguo Li
    Ann Rheum Dis Published Online First: 3 May 2013 doi:10.1136/annrheumdis-2012-202444
    Basic and translational research: Extended Report: Deletion of the receptor tyrosine kinase Tyro3 inhibits synovial hyperplasia and bone damage in arthritis
    • Gisela Ruiz-Heiland,
    • Yi Zhao,
    • Anja Derer,
    • Tobias Braun,
    • Klaus Engelke,
    • Elena Neumann,
    • Ulf Mueller-Ladner,
    • Yi Liu,
    • Jochen Zwerina,
    • Georg Schett
    Ann Rheum Dis Published Online First: 30 April 2013 doi:10.1136/annrheumdis-2012-202907
    Basic and translational research: Extended report: Changes in biomarkers after therapeutic intervention in temporal arteries cultured in Matrigel: a new model for preclinical studies in giant-cell arteritis
    • Marc Corbera-Bellalta,
    • Ana García-Martínez,
    • Ester Lozano,
    • Ester Planas-Rigol,
    • Itziar Tavera-Bahillo,
    • Marco A Alba,
    • Sergio Prieto-González,
    • Montserrat Butjosa,
    • Georgina Espígol-Frigolé,
    • José Hernández-Rodríguez,
    • Pedro L Fernández,
    • Pascale Roux-Lombard,
    • Jean-Michel Dayer,
    • Mahboob U Rahman,
    • Maria C Cid
    Ann Rheum Dis Published Online First: 27 April 2013 doi:10.1136/annrheumdis-2012-202883
    Basic and translational research: Extended report: Anakinra treatment in patients with refractory inflammatory myopathies and possible predictive response biomarkers: a mechanistic study with 12 months follow-up
    • Mei Zong,
    • Christina Dorph,
    • Maryam Dastmalchi,
    • Helene Alexanderson,
    • Jennifer Pieper,
    • Petra Amoudruz,
    • Sevim Barbasso Helmers,
    • Inger Nennesmo,
    • Vivianne Malmström,
    • Ingrid E Lundberg
    Ann Rheum Dis Published Online First: 26 April 2013 doi:10.1136/annrheumdis-2012-202857
    Basic and translational research: Extended report: Expression of aberrant HLA-B27 molecules is dependent on B27 dosage and peptide supply
    • Kirsty McHugh,
    • Oliwia Rysnik,
    • Simon Kollnberger,
    • Jacqueline Shaw,
    • Lotta Utriainen,
    • Mohammad Hussein Al-Mossawi,
    • Sravan Payeli,
    • Osiris Marroquin,
    • Simon Milling,
    • Christoph Renner,
    • Paul Bowness
    Ann Rheum Dis Published Online First: 26 April 2013 doi:10.1136/annrheumdis-2012-203080
    Basic and translational research: Concise report: Circulating plasmablasts/plasmacells as a source of anticitrullinated protein antibodies in patients with rheumatoid arthritis
    • Priscilla F Kerkman,
    • Yoann Rombouts,
    • Ellen I H van der Voort,
    • Leendert A Trouw,
    • Tom W J Huizinga,
    • René EM Toes,
    • Hans U Scherer
    Ann Rheum Dis Published Online First: 26 April 2013 doi:10.1136/annrheumdis-2012-202893
    Basic and translational research: Extended report: Osteoarthritis development is induced by increased dietary cholesterol and can be inhibited by atorvastatin in APOE*3Leiden.CETP mice—a translational model for atherosclerosis
    • L M Gierman,
    • S Kühnast,
    • A Koudijs,
    • E J Pieterman,
    • M Kloppenburg,
    • G J V M van Osch,
    • V Stojanovic-Susulic,
    • T W J Huizinga,
    • H M G Princen,
    • A-M Zuurmond
    Ann Rheum Dis Published Online First: 26 April 2013 doi:10.1136/annrheumdis-2013-203248
    Basic and translational research: Extended report: Peripheral joint inflammation in early onset spondyloarthritis is not specifically related to enthesitis
    • Jacqueline E Paramarta,
    • Christiaan van der Leij,
    • Ioana Gofita,
    • Nataliya Yeremenko,
    • Marleen G van de Sande,
    • Maria J de Hair,
    • Paul P Tak,
    • Mario Maas,
    • Dominique Baeten
    Ann Rheum Dis Published Online First: 25 April 2013 doi:10.1136/annrheumdis-2012-203155
    Basic and translational research: Extended report: Rheumatoid arthritis synovial tissue harbours dominant B-cell and plasma-cell clones associated with autoreactivity
    • M E Doorenspleet,
    • P L Klarenbeek,
    • M J H de Hair,
    • B D C van Schaik,
    • R E E Esveldt,
    • A H C van Kampen,
    • D M Gerlag,
    • A Musters,
    • F Baas,
    • P P Tak,
    • N de Vries
    Ann Rheum Dis Published Online First: 20 April 2013 doi:10.1136/annrheumdis-2012-202861
    Basic and translational research: Concise report: Blockade of canonical Wnt signalling ameliorates experimental dermal fibrosis
    • Christian Beyer,
    • Helena Reichert,
    • Hümeyra Akan,
    • Tatjana Mallano,
    • Amelie Schramm,
    • Clara Dees,
    • Katrin Palumbo-Zerr,
    • Neng Yu Lin,
    • Alfiya Distler,
    • Kolja Gelse,
    • John Varga,
    • Oliver Distler,
    • Georg Schett,
    • Jörg H W Distler
    Ann Rheum Dis Published Online First: 17 April 2013 doi:10.1136/annrheumdis-2012-202544
    Basic and translational research: Extended report: Impaired serum cholesterol efflux capacity in rheumatoid arthritis and systemic lupus erythematosus
    • Nicoletta Ronda,
    • Elda Favari,
    • Maria Orietta Borghi,
    • Francesca Ingegnoli,
    • Maria Gerosa,
    • Cecilia Chighizola,
    • Francesca Zimetti,
    • Maria Pia Adorni,
    • Franco Bernini,
    • Pier Luigi Meroni
    Ann Rheum Dis Published Online First: 5 April 2013 doi:10.1136/annrheumdis-2012-202914
    Basic and translational research: Extended report: A synthetic PPAR-γ agonist triterpenoid ameliorates experimental fibrosis: PPAR-γ-independent suppression of fibrotic responses
    • Jun Wei,
    • Hongyan Zhu,
    • Kazuhiro Komura,
    • Gabriel Lord,
    • Michal Tomcik,
    • Wenxia Wang,
    • Sruthi Doniparthi,
    • Zenshiro Tamaki,
    • Monique Hinchcliff,
    • Joerg H W Distler,
    • John Varga
    Ann Rheum Dis Published Online First: 20 March 2013 doi:10.1136/annrheumdis-2012-202716
    Basic and translational research: Extended report: Ochronotic osteoarthropathy in a mouse model of alkaptonuria, and its inhibition by nitisinone
    • Andrew J Preston,
    • Craig M Keenan,
    • Hazel Sutherland,
    • Peter J Wilson,
    • Brenda Wlodarski,
    • Adam M Taylor,
    • Dominic P Williams,
    • Lakshminarayan R Ranganath,
    • James A Gallagher,
    • Jonathan C Jarvis
    Ann Rheum Dis Published Online First: 19 March 2013 doi:10.1136/annrheumdis-2012-202878
    Basic and translational research: Extended report: The enhanced liver fibrosis test: a clinical grade, validated serum test, biomarker of overall fibrosis in systemic sclerosis
    • Giuseppina Abignano,
    • Giovanna Cuomo,
    • Maya H Buch,
    • William M Rosenberg,
    • Gabriele Valentini,
    • Paul Emery,
    • Francesco Del Galdo
    Ann Rheum Dis Published Online First: 19 March 2013 doi:10.1136/annrheumdis-2012-202843
    Basic and translational research: Extended report: Identification of a new exon 2-skipped TNFR1 transcript: regulation by three functional polymorphisms of the TNFR-associated periodic syndrome (TRAPS) gene
    • Cécile Rittore,
    • Elodie Sanchez,
    • Stephan Soler,
    • Mouna Barat-Houari,
    • Marieke Albers,
    • Laura Obici,
    • Michael F McDermott,
    • Isabelle Touitou,
    • Sylvie Grandemange
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-203023
    Basic and translational research: Extended report: Increased NLRP3-dependent interleukin 1β secretion in patients with familial Mediterranean fever: correlation with MEFV genotype
    • Alessia Omenetti,
    • Sonia Carta,
    • Laura Delfino,
    • Alberto Martini,
    • Marco Gattorno,
    • Anna Rubartelli
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202774
    Basic and translational research: Extended report: MEFV mutations affecting pyrin amino acid 577 cause autosomal dominant autoinflammatory disease
    • Monique Stoffels,
    • Agata Szperl,
    • Anna Simon,
    • Mihai G Netea,
    • Theo S Plantinga,
    • Marcel van Deuren,
    • Sylvia Kamphuis,
    • Helen J Lachmann,
    • Edwin Cuppen,
    • Wigard P Kloosterman,
    • Joost Frenkel,
    • Cleo C van Diemen,
    • Cisca Wijmenga,
    • Marielle van Gijn,
    • Jos W M van der Meer
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202580
    Basic and translational research: Extended report: IL-7 receptor α expressing B cells act proinflammatory in collagen-induced arthritis and are inhibited by sympathetic neurotransmitters
    • Georg Pongratz,
    • Judith M Anthofer,
    • Madlen Melzer,
    • Sven Anders,
    • Susanne Grässel,
    • Rainer H Straub
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202944
    Basic and translational research: Extended report: Lysophosphatidic acid receptor inhibition as a new multipronged treatment for rheumatoid arthritis
    • Beatriz Orosa,
    • Samuel García,
    • Paula Martínez,
    • Antonio González,
    • Juan J Gómez-Reino,
    • Carmen Conde
    Ann Rheum Dis Published Online First: 13 March 2013 doi:10.1136/annrheumdis-2012-202832
    Basic and translational research: Extended report: Urinary CD4 T cells identify SLE patients with proliferative lupus nephritis and can be used to monitor treatment response
    • Philipp Enghard,
    • Claudia Rieder,
    • Katharina Kopetschke,
    • J R Klocke,
    • Reinmar Undeutsch,
    • Robert Biesen,
    • Duska Dragun,
    • Maik Gollasch,
    • Udo Schneider,
    • Karlfried Aupperle,
    • Jens Y Humrich,
    • Falk Hiepe,
    • Marina Backhaus,
    • A H Radbruch,
    • Gerd R Burmester,
    • Gabriela Riemekasten
    Ann Rheum Dis Published Online First: 8 March 2013 doi:10.1136/annrheumdis-2012-202784
    Basic and translational research: Extended report: Heightened immune response to autocitrullinated Porphyromonas gingivalis peptidylarginine deiminase: a potential mechanism for breaching immunologic tolerance in rheumatoid arthritis
    • Anne-Marie Quirke,
    • Elena Birgitta Lugli,
    • Natalia Wegner,
    • Bart C Hamilton,
    • Peter Charles,
    • Muslima Chowdhury,
    • A Jimmy Ytterberg,
    • Roman A Zubarev,
    • Jan Potempa,
    • Shauna Culshaw,
    • Yonghua Guo,
    • Benjamin A Fisher,
    • Geoffrey Thiele,
    • Ted R Mikuls,
    • Patrick JW Venables
    Ann Rheum Dis Published Online First: 5 March 2013 doi:10.1136/annrheumdis-2012-202726
    Open Access
    Basic and translational research: Extended report: Low-avidity anticitrullinated protein antibodies (ACPA) are associated with a higher rate of joint destruction in rheumatoid arthritis
    • Parawee Suwannalai,
    • Karin Britsemmer,
    • Rachel Knevel,
    • Hans Ulrich Scherer,
    • E W Nivine Levarht,
    • Annette H van der Helm-van Mil,
    • Dirkjan van Schaardenburg,
    • Tom W J Huizinga,
    • René E M Toes,
    • L A Trouw
    Ann Rheum Dis Published Online First: 5 March 2013 doi:10.1136/annrheumdis-2012-202615
    Basic and translational research: Extended report: New insight on the Xq28 association with systemic sclerosis
    • F David Carmona,
    • M Carmen Cénit,
    • Lina-Marcela Diaz-Gallo,
    • Jasper C A Broen,
    • Carmen P Simeón,
    • Patricia E Carreira,
    • José-Luis Callejas-Rubio,
    • Vicente Fonollosa,
    • Francisco J López-Longo,
    • Miguel A González-Gay,
    • Nicolas Hunzelmann,
    • Gabriela Riemekasten,
    • Torsten Witte,
    • Alexander Kreuter,
    • Jörg H W Distler,
    • Rajan Madhok,
    • Paul Shiels,
    • Jacob M van Laar,
    • Annemie J Schuerwegh,
    • Madelon C Vonk,
    • Alexandre E Voskuyl,
    • Carmen Fonseca,
    • Christopher P Denton,
    • Ariane Herrick,
    • Jane Worthington,
    • Frank C Arnett,
    • Filemon K Tan,
    • Shervin Assassi,
    • Timothy R D J Radstake,
    • Maureen D Mayes,
    • Javier Martín
    Ann Rheum Dis Published Online First: 26 February 2013 doi:10.1136/annrheumdis-2012-202742
    Basic and translational research: Extended report: The liver X receptor pathway is highly upregulated in rheumatoid arthritis synovial macrophages and potentiates TLR-driven cytokine release
    • Darren Lee Asquith,
    • Lucy E Ballantine,
    • Jagtar Singh Nijjar,
    • Manhal Khuder Makdasy,
    • Sabina Patel,
    • Pamela B Wright,
    • James H Reilly,
    • Shauna Kerr,
    • Mariola Kurowska-Stolarska,
    • J Alastair Gracie,
    • Iain B McInnes
    Ann Rheum Dis Published Online First: 23 February 2013 doi:10.1136/annrheumdis-2012-202872
    Basic and translational research: Extended report: A phase 1b clinical trial evaluating sifalimumab, an anti-IFN-α monoclonal antibody, shows target neutralisation of a type I IFN signature in blood of dermatomyositis and polymyositis patients
    • Brandon W Higgs,
    • Wei Zhu,
    • Chris Morehouse,
    • Wendy I White,
    • Philip Brohawn,
    • Xiang Guo,
    • Marlon Rebelatto,
    • Chenxiong Le,
    • Anthony Amato,
    • David Fiorentino,
    • Steven A Greenberg,
    • Jorn Drappa,
    • Laura Richman,
    • Warren Greth,
    • Bahija Jallal,
    • Yihong Yao
    Ann Rheum Dis Published Online First: 23 February 2013 doi:10.1136/annrheumdis-2012-202794
    Open Access
    Basic and translational research: Extended report: Virtual skin biopsy by optical coherence tomography: the first quantitative imaging biomarker for scleroderma
    • Giuseppina Abignano,
    • Sibel Zehra Aydin,
    • Concepción Castillo-Gallego,
    • Vasiliki Liakouli,
    • Daniel Woods,
    • Adam Meekings,
    • Richard J Wakefield,
    • Dennis G McGonagle,
    • Paul Emery,
    • Francesco Del Galdo
    Ann Rheum Dis Published Online First: 20 February 2013 doi:10.1136/annrheumdis-2012-202682
    Basic and translational research: Extended report: Regulation of matrixmetalloproteinase-3 and matrixmetalloproteinase-13 by SUMO-2/3 through the transcription factor NF-κB
    • Svetlana Frank,
    • Marvin A Peters,
    • Corinna Wehmeyer,
    • Simon Strietholt,
    • Christina Koers-Wunrau,
    • Jessica Bertrand,
    • Marianne Heitzmann,
    • Anja Hillmann,
    • Joanna Sherwood,
    • Christine Seyfert,
    • Steffen Gay,
    • Thomas Pap
    Ann Rheum Dis Published Online First: 16 February 2013 doi:10.1136/annrheumdis-2012-202080
    Basic and translational research: Extended report: NKG2D stimulated T-cell autoreactivity in giant cell arteritis and polymyalgia rheumatica
    • Christian Dejaco,
    • Christina Duftner,
    • Juman Al-Massad,
    • Annette D Wagner,
    • Joon-Keun Park,
    • Johannes Fessler,
    • Ariane Aigelsreiter,
    • Franz Hafner,
    • Sandra Vega,
    • William Sterlacci,
    • Beatrix Grubeck-Loebenstein,
    • Alexander Tzankov,
    • Thomas Ness,
    • Luigi Boiardi,
    • Carlo Salvarani,
    • Michael Schirmer
    Ann Rheum Dis Published Online First: 15 February 2013 doi:10.1136/annrheumdis-2012-201660
    Basic and translational research: Extended report: A profibrotic role for thymic stromal lymphopoietin in systemic sclerosis
    • Alicia Usategui,
    • Gabriel Criado,
    • Elena Izquierdo,
    • Manuel J Del Rey,
    • Patricia E Carreira,
    • Pablo Ortiz,
    • Warren J Leonard,
    • José L Pablos
    Ann Rheum Dis Published Online First: 14 February 2013 doi:10.1136/annrheumdis-2012-202279
    Basic and translational research: Extended report: Interleukin-1 receptor antagonist deficient mice provide insights into pathogenesis of human intervertebral disc degeneration
    • Kate Louise Eve Phillips,
    • Nikki Jordan-Mahy,
    • Martin J H Nicklin,
    • Christine Lyn Le Maitre
    Ann Rheum Dis Published Online First: 9 February 2013 doi:10.1136/annrheumdis-2012-202266
    Basic and translational research: Extended report: Population-specific influence of SLC2A9 genotype on the acute hyperuricaemic response to a fructose load
    • Nicola Dalbeth,
    • Meaghan E House,
    • Gregory D Gamble,
    • Anne Horne,
    • Bregina Pool,
    • Lauren Purvis,
    • Angela Stewart,
    • Marilyn Merriman,
    • Murray Cadzow,
    • Amanda Phipps-Green,
    • Tony R Merriman
    Ann Rheum Dis Published Online First: 24 January 2013 doi:10.1136/annrheumdis-2012-202732
    Basic and translational research: Extended report: Aryl hydrocarbon receptor antagonism mitigates cytokine-mediated inflammatory signalling in primary human fibroblast-like synoviocytes
    • Tejas S Lahoti,
    • Kaarthik John,
    • Jarod M Hughes,
    • Ann Kusnadi,
    • Iain A Murray,
    • Gowdahalli Krishnegowda,
    • Shantu Amin,
    • Gary H Perdew
    Ann Rheum Dis Published Online First: 24 January 2013 doi:10.1136/annrheumdis-2012-202639
    Basic and translational research: Extended report: IL-17/Th17 mediated synovial inflammation is IL-22 independent
    • Jan Piet van Hamburg,
    • Odilia B J Corneth,
    • Sandra M J Paulissen,
    • Nadine Davelaar,
    • Patrick S Asmawidjaja,
    • Adriana M C Mus,
    • Erik Lubberts
    Ann Rheum Dis Published Online First: 17 January 2013 doi:10.1136/annrheumdis-2012-202373
    Basic and translational research: Extended report: High density lipoprotein is targeted for oxidation by myeloperoxidase in rheumatoid arthritis
    • Anuradha Vivekanandan-Giri,
    • Jessica L Slocum,
    • Jaeman Byun,
    • Chongren Tang,
    • Robin L Sands,
    • Brenda W Gillespie,
    • Jay W Heinecke,
    • Rajiv Saran,
    • Mariana J Kaplan,
    • Subramaniam Pennathur
    Ann Rheum Dis Published Online First: 12 January 2013 doi:10.1136/annrheumdis-2012-202033
    Basic and translational research: Extended report: Nicotinamide phosphoribosyltransferase/visfatin expression by inflammatory monocytes mediates arthritis pathogenesis
    • Jessy Présumey,
    • Gabriel Courties,
    • Pascale Louis-Plence,
    • Virginie Escriou,
    • Daniel Scherman,
    • Yves-Marie Pers,
    • Hans Yssel,
    • Jérôme Pène,
    • Diego Kyburz,
    • Steffen Gay,
    • Christian Jorgensen,
    • Florence Apparailly
    Ann Rheum Dis Published Online First: 12 January 2013 doi:10.1136/annrheumdis-2012-202403
    Basic and translational research: Extended report: Long-term measurement of anti-adalimumab using pH-shift-anti-idiotype antigen binding test shows predictive value and transient antibody formation
    • Pauline A van Schouwenburg,
    • Charlotte L Krieckaert,
    • Theo Rispens,
    • Lucien Aarden,
    • Gerrit Jan Wolbink,
    • Diana Wouters
    Ann Rheum Dis Published Online First: 7 January 2013 doi:10.1136/annrheumdis-2012-202407
    Basic and translational research: Extended report: Toll-like receptor 4 in bone marrow-derived cells as well as tissue-resident cells participate in aggravating autoimmune destructive arthritis
    • Ben T van den Brand,
    • Shahla Abdollahi-Roodsaz,
    • Miranda B Bennink,
    • Johan Bussink,
    • Onno J Arntz,
    • Wim B van den Berg,
    • Fons A J van de Loo
    Ann Rheum Dis Published Online First: 3 January 2013 doi:10.1136/annrheumdis-2012-202467
    Basic and translational research: Extended report: Epstein–Barr virus persistence and infection of autoreactive plasma cells in synovial lymphoid structures in rheumatoid arthritis
    • Cristina Croia,
    • Barbara Serafini,
    • Michele Bombardieri,
    • Stephen Kelly,
    • Frances Humby,
    • Martina Severa,
    • Fabiana Rizzo,
    • Eliana Marina Coccia,
    • Paola Migliorini,
    • Francesca Aloisi,
    • Costantino Pitzalis
    Ann Rheum Dis Published Online First: 25 December 2012 doi:10.1136/annrheumdis-2012-202352
    Basic and translational research: Extended report: The novel cytokine interleukin-36α is expressed in psoriatic and rheumatoid arthritis synovium
    • Silke Frey,
    • Anja Derer,
    • Maria-Elena Messbacher,
    • Dominique L P Baeten,
    • Serena Bugatti,
    • Carlomaurizio Montecucco,
    • Georg Schett,
    • Axel J Hueber
    Ann Rheum Dis Published Online First: 25 December 2012 doi:10.1136/annrheumdis-2012-202264
    Basic and translational research: Extended report: Foxp3+ Helios+ regulatory T cells are expanded in active systemic lupus erythematosus
    • Tobias Alexander,
    • Arne Sattler,
    • Lars Templin,
    • Siegfried Kohler,
    • Christian Groß,
    • Andreas Meisel,
    • Birgit Sawitzki,
    • Gerd-Rüdiger Burmester,
    • Renate Arnold,
    • Andreas Radbruch,
    • Andreas Thiel,
    • Falk Hiepe
    Ann Rheum Dis Published Online First: 21 December 2012 doi:10.1136/annrheumdis-2012-202216
    Basic and translational research: Extended report: Citrullination enhances the pro-inflammatory response to fibrin in rheumatoid arthritis synovial fibroblasts
    • Olga Sanchez-Pernaute,
    • Maria Filkova,
    • Antonio Gabucio,
    • Martin Klein,
    • Hanna Maciejewska-Rodrigues,
    • Caroline Ospelt,
    • Fabia Brentano,
    • Beat A Michel,
    • Renate E Gay,
    • Gabriel Herrero-Beaumont,
    • Steffen Gay,
    • Michel Neidhart,
    • Astrid Juengel
    Ann Rheum Dis Published Online First: 12 December 2012 doi:10.1136/annrheumdis-2012-201906
    Basic and translational research: Extended report: Genome-wide association analysis of anti-TNF drug response in patients with rheumatoid arthritis
    • Maša Umiċeviċ Mirkov,
    • Jing Cui,
    • Sita H Vermeulen,
    • Eli A Stahl,
    • Erik J M Toonen,
    • Remco R Makkinje,
    • Annette T Lee,
    • Tom W J Huizinga,
    • Renee Allaart,
    • Anne Barton,
    • Xavier Mariette,
    • Corinne Richard Miceli,
    • Lindsey A Criswell,
    • Paul P Tak,
    • Niek de Vries,
    • Saedis Saevarsdottir,
    • Leonid Padyukov,
    • S Louis Bridges,
    • Dirk-Jan van Schaardenburg,
    • Tim L Jansen,
    • Ellen A J Dutmer,
    • Mart A F J van de Laar,
    • Pilar Barrera,
    • Timothy R D J Radstake,
    • Piet L C M van Riel,
    • Hans Scheffer,
    • Barbara Franke,
    • Han G Brunner,
    • Robert M Plenge,
    • Peter K Gregersen,
    • Henk-Jan Guchelaar,
    • Marieke J H Coenen
    Ann Rheum Dis Published Online First: 11 December 2012 doi:10.1136/annrheumdis-2012-202405
    Basic and translational research: Extended report: Identification of the NF-κB activating protein-like locus as a risk locus for rheumatoid arthritis
    • Gang Xie,
    • Yue Lu,
    • Ye Sun,
    • Steven Shiyang Zhang,
    • Edward Clark Keystone,
    • Peter K Gregersen,
    • Robert M Plenge,
    • Christopher I Amos,
    • Katherine A Siminovitch
    Ann Rheum Dis Published Online First: 6 December 2012 doi:10.1136/annrheumdis-2012-202076
    Open Access
    Basic and translational research: Extended report: Toll-like receptor-mediated, enhanced production of profibrotic TIMP-1 in monocytes from patients with systemic sclerosis: role of serum factors
    • Marzena Ciechomska,
    • Christiaan A Huigens,
    • Thomas Hügle,
    • Tess Stanly,
    • Andreas Gessner,
    • Bridget Griffiths,
    • Timothy R D J Radstake,
    • Sophie Hambleton,
    • Steven O'Reilly,
    • Jacob M van Laar
    Ann Rheum Dis Published Online First: 6 December 2012 doi:10.1136/annrheumdis-2012-201958
    Basic and translational research: Extended report: The TNF family member APRIL dampens collagen-induced arthritis
    • Leticia Fernandez,
    • Gabriela Franco Salinas,
    • Cecilia Rocha,
    • Carla E Carvalho-Pinto,
    • Nataliya Yeremenko,
    • Laura Papon,
    • Jan Paul Medema,
    • Bernard Combe,
    • Jacques Morel,
    • Dominique Baeten,
    • Michael Hahne
    Ann Rheum Dis Published Online First: 24 November 2012 doi:10.1136/annrheumdis-2012-202382
    Basic and translational research: Extended report: Implication of IL-2/IL-21 region in systemic sclerosis genetic susceptibility
    • Lina-Marcela Diaz-Gallo,
    • Carmen P Simeon,
    • Jasper C Broen,
    • Norberto Ortego-Centeno,
    • Lorenzo Beretta,
    • Madelon C Vonk,
    • Patricia E Carreira,
    • Sofia Vargas,
    • José Andrés Román-Ivorra,
    • Miguel A González-Gay,
    • Carlos Tolosa,
    • Francisco Javier López-Longo,
    • Gerard Espinosa,
    • Esther F Vicente,
    • Roger Hesselstrand,
    • Gabriela Riemekasten,
    • Torsten Witte,
    • Jörg H W Distler,
    • Alexandre E Voskuyl,
    • Annemie J Schuerwegh,
    • Paul G Shiels,
    • Annika Nordin,
    • Leonid Padyukov,
    • Anna-Maria Hoffmann-Vold,
    • Raffaella Scorza,
    • Claudio Lunardi,
    • Paolo Airo,
    • Jacob M van Laar,
    • Nicolas Hunzelmann,
    • Birgit S Gathof,
    • Alexander Kreuter,
    • Ariane Herrick,
    • Jane Worthington,
    • Christopher P Denton,
    • Xiaodong Zhou,
    • Frank C Arnett,
    • Carmen Fonseca,
    • Bobby PC Koeleman,
    • Shervin Assasi,
    • Timothy R D J Radstake,
    • Maureen D Mayes,
    • Javier Martín,
    • The Spanish Scleroderma Group
    Ann Rheum Dis Published Online First: 21 November 2012 doi:10.1136/annrheumdis-2012-202357
    Basic and translational research: Extended report: The cathelicidins LL-37 and rCRAMP are associated with pathogenic events of arthritis in humans and rats
    • Markus H Hoffmann,
    • Heiko Bruns,
    • Liselotte Bäckdahl,
    • Petra Neregård,
    • Birgit Niederreiter,
    • Martin Herrmann,
    • Anca Irinel Catrina,
    • Birgitta Agerberth,
    • Rikard Holmdahl
    Ann Rheum Dis Published Online First: 21 November 2012 doi:10.1136/annrheumdis-2012-202218
    Basic and translational research: Extended report: TLR4 as receptor for HMGB1 induced muscle dysfunction in myositis
    • Mei Zong,
    • Joseph D Bruton,
    • Cecilia Grundtman,
    • Huan Yang,
    • Jian Hua Li,
    • Helene Alexanderson,
    • Karin Palmblad,
    • Ulf Andersson,
    • Helena E Harris,
    • Ingrid E Lundberg,
    • Håkan Westerblad
    Ann Rheum Dis Published Online First: 12 November 2012 doi:10.1136/annrheumdis-2012-202207
    Basic and translational research: Concise report: Inactivation of tankyrases reduces experimental fibrosis by inhibiting canonical Wnt signalling
    • Alfiya Distler,
    • Lisa Deloch,
    • Jingang Huang,
    • Clara Dees,
    • Neng-Yu Lin,
    • Katrin Palumbo-Zerr,
    • Christian Beyer,
    • Alexander Weidemann,
    • Oliver Distler,
    • Georg Schett,
    • Jörg H W Distler
    Ann Rheum Dis Published Online First: 12 November 2012 doi:10.1136/annrheumdis-2012-202275
    Basic and translational research: Extended report: C57BL/6 mice need MHC class II Aq to develop collagen-induced arthritis dependent on autoreactive T cells
    • Johan Bäcklund,
    • Cuiqin Li,
    • Erik Jansson,
    • Stefan Carlsen,
    • Patrick Merky,
    • Kutty-Selva Nandakumar,
    • Sabrina Haag,
    • Jimmy Ytterberg,
    • Roman A Zubarev,
    • Rikard Holmdahl
    Ann Rheum Dis Published Online First: 5 October 2012 doi:10.1136/annrheumdis-2012-202055

Clinical and epidemiological research

    Clinical and epidemiological research: Extended report: Efficacy and safety of open-label etanercept on extended oligoarticular juvenile idiopathic arthritis, enthesitis-related arthritis and psoriatic arthritis: part 1 (week 12) of the CLIPPER study
    • Gerd Horneff,
    • Ruben Burgos-Vargas,
    • Tamas Constantin,
    • Ivan Foeldvari,
    • Jelena Vojinovic,
    • Vyacheslav G Chasnyk,
    • Joke Dehoorne,
    • Violeta Panaviene,
    • Gordana Susic,
    • Valda Stanevica,
    • Katarzyna Kobusinska,
    • Zbigniew Zuber,
    • Richard Mouy,
    • Ingrida Rumba-Rozenfelde,
    • Luciana Breda,
    • Pavla Dolezalova,
    • Chantal Job-Deslandre,
    • Nico Wulffraat,
    • Daniel Alvarez,
    • Chuanbo Zang,
    • Joseph Wajdula,
    • Deborah Woodworth,
    • Bonnie Vlahos,
    • Alberto Martini,
    • Nicolino Ruperto
    Ann Rheum Dis Published Online First: 21 May 2013 doi:10.1136/annrheumdis-2012-203046
    Open Access
    Clinical and epidemiological research: Extended report: Efficacy and safety of infliximab plus naproxen versus naproxen alone in patients with early, active axial spondyloarthritis: results from the double-blind, placebo-controlled INFAST study, Part 1
    • J Sieper,
    • J Lenaerts,
    • J Wollenhaupt,
    • M Rudwaleit,
    • V I Mazurov,
    • L Myasoutova,
    • S Park,
    • Y Song,
    • R Yao,
    • D Chitkara,
    • N Vastesaeger
    Ann Rheum Dis Published Online First: 21 May 2013 doi:10.1136/annrheumdis-2012-203201
    Clinical and epidemiological research: Extended Report: Evidence-based detection of pulmonary arterial hypertension in systemic sclerosis: the DETECT study
    • J Gerry Coghlan,
    • Christopher P Denton,
    • Ekkehard Grünig,
    • Diana Bonderman,
    • Oliver Distler,
    • Dinesh Khanna,
    • Ulf Müller-Ladner,
    • Janet E Pope,
    • Madelon C Vonk,
    • Martin Doelberg,
    • Harbajan Chadha-Boreham,
    • Harald Heinzl,
    • Daniel M Rosenberg,
    • Vallerie V McLaughlin,
    • James R Seibold
    Ann Rheum Dis Published Online First: 18 May 2013 doi:10.1136/annrheumdis-2013-203301
    Open Access
    Clinical and epidemiological research: Extended Report: Primary Sjögren's syndrome and malignancy risk: a systematic review and meta-analysis
    • Yan Liang,
    • Zaixing Yang,
    • Baodong Qin,
    • Renqian Zhong
    Ann Rheum Dis Published Online First: 17 May 2013 doi:10.1136/annrheumdis-2013-203305
    Clinical and epidemiological research: Extended report: A randomised, double-blind, parallel-group study to demonstrate equivalence in efficacy and safety of CT-P13 compared with innovator infliximab when coadministered with methotrexate in patients with active rheumatoid arthritis: the PLANETRA study
    • Dae Hyun Yoo,
    • Pawel Hrycaj,
    • Pedro Miranda,
    • Edgar Ramiterre,
    • Mariusz Piotrowski,
    • Sergii Shevchuk,
    • Volodymyr Kovalenko,
    • Nenad Prodanovic,
    • Mauricio Abello-Banfi,
    • Sergio Gutierrez-Ureña,
    • Luis Morales-Olazabal,
    • Michael Tee,
    • Renato Jimenez,
    • Omid Zamani,
    • Sang Joon Lee,
    • HoUng Kim,
    • Won Park,
    • Ulf Müller-Ladner
    Ann Rheum Dis Published Online First: 16 May 2013 doi:10.1136/annrheumdis-2012-203090
    Open Access
    Clinical and epidemiological research: Extended report: A randomised, double-blind, multicentre, parallel-group, prospective study comparing the pharmacokinetics, safety, and efficacy of CT-P13 and innovator infliximab in patients with ankylosing spondylitis: the PLANETAS study
    • Won Park,
    • Pawel Hrycaj,
    • Slawomir Jeka,
    • Volodymyr Kovalenko,
    • Grygorii Lysenko,
    • Pedro Miranda,
    • Helena Mikazane,
    • Sergio Gutierrez-Ureña,
    • MieJin Lim,
    • Yeon-Ah Lee,
    • Sang Joon Lee,
    • HoUng Kim,
    • Dae Hyun Yoo,
    • Jürgen Braun
    Ann Rheum Dis Published Online First: 16 May 2013 doi:10.1136/annrheumdis-2012-203091
    Open Access
    Clinical and epidemiological research: Extended Report: A preliminary algorithm introducing immunogenicity assessment in the management of patients with RA receiving tumour necrosis factor inhibitor therapies
    • Sandra Garcês,
    • Marília Antunes,
    • Elizabeth Benito-Garcia,
    • José Canas da Silva,
    • Lucien Aarden,
    • Jocelyne Demengeot
    Ann Rheum Dis Published Online First: 11 May 2013 doi:10.1136/annrheumdis-2013-203296
    Clinical and epidemiological research: Extended Report: Postoperative effects of neuromuscular exercise prior to hip or knee arthroplasty: a randomised controlled trial
    • Allan Villadsen,
    • Søren Overgaard,
    • Anders Holsgaard-Larsen,
    • Robin Christensen,
    • Ewa M Roos
    Ann Rheum Dis Published Online First: 9 May 2013 doi:10.1136/annrheumdis-2012-203135
    Clinical and epidemiological research: Concise Report: Long-term outcome of Rheumatoid Arthritis defined according to the 2010-classification criteria
    • L E Burgers,
    • J A B van Nies,
    • L Y Ho,
    • D P C de Rooy,
    • T W J Huizinga,
    • A H M van der Helm-van Mil
    Ann Rheum Dis Published Online First: 9 May 2013 doi:10.1136/annrheumdis-2013-203402
    Clinical and epidemiological research: Extended Report: Periarticular and generalised bone loss in patients with early rheumatoid arthritis: influence of alendronate and intra-articular glucocorticoid treatment. Post hoc analyses from the CIMESTRA trial
    • T W Jensen,
    • M S Hansen,
    • K Hørslev-Petersen,
    • L Hyldstrup,
    • B Abrahamsen,
    • B Langdahl,
    • B Zerahn,
    • J Pødenphant,
    • K Stengaard-Petersen,
    • P Junker,
    • M Østergaard,
    • T Lottenburger,
    • T Ellingsen,
    • L S Andersen,
    • I Hansen,
    • H Skjødt,
    • J K Pedersen,
    • U B Lauridsen,
    • A J Svendsen,
    • U Tarp,
    • H Lindegaard,
    • Anne Grethe Jurik,
    • Aage Vestergaard,
    • M L Hetland
    Ann Rheum Dis Published Online First: 9 May 2013 doi:10.1136/annrheumdis-2012-203171
    Clinical and epidemiological research: Concise Report: The risk of gastrointestinal perforations in patients with rheumatoid arthritis treated with anti-TNF therapy: results from the BSRBR-RA
    • Jakub Závada,
    • Mark Lunt,
    • Rebecca Davies,
    • Audrey SL Low,
    • Louise K Mercer,
    • James B Galloway,
    • Kath D Watson,
    • Deborah P Symmons,
    • Kimme L Hyrich
    Ann Rheum Dis Published Online First: 5 May 2013 doi:10.1136/annrheumdis-2012-203102
    Clinical and epidemiological research: Extended Report: Suppression of inflammation reduces endothelial microparticles in active systemic lupus erythematosus
    • Ben Parker,
    • Awal Al-Husain,
    • Philip Pemberton,
    • Allen P Yates,
    • Pauline Ho,
    • Rachel Gorodkin,
    • Lee Suan Teh,
    • M Yvonne Alexander,
    • Ian N Bruce
    Ann Rheum Dis Published Online First: 5 May 2013 doi:10.1136/annrheumdis-2012-203028
    Open Access
    Clinical and epidemiological research: Concise Report: Correlations between nailfold microangiopathy severity, finger dermal thickness and fingertip blood perfusion in systemic sclerosis patients
    • A Sulli,
    • B Ruaro,
    • E Alessandri,
    • C Pizzorni,
    • M A Cimmino,
    • G Zampogna,
    • M Gallo,
    • M Cutolo
    Ann Rheum Dis Published Online First: 3 May 2013 doi:10.1136/annrheumdis-2012-202572
    Clinical and epidemiological research: Extended Report: High prevalence of anti-CD74 antibodies specific for the HLA class II-associated invariant chain peptide (CLIP) in patients with axial spondyloarthritis
    • X Baraliakos,
    • N Baerlecken,
    • T Witte,
    • F Heldmann,
    • J Braun
    Ann Rheum Dis Published Online First: 3 May 2013 doi:10.1136/annrheumdis-2012-202177
    Clinical and epidemiological research: Extended report: The effect of two golimumab doses on radiographic progression in ankylosing spondylitis: results through 4 years of the GO-RAISE trial
    • Jürgen Braun,
    • Xenofon Baraliakos,
    • Kay-Geert A Hermann,
    • Atul Deodhar,
    • Désirée van der Heijde,
    • Robert Inman,
    • Anna Beutler,
    • Yiying Zhou,
    • Stephen Xu,
    • Benjamin Hsu
    Ann Rheum Dis Published Online First: 3 May 2013 doi:10.1136/annrheumdis-2012-203075
    Open Access
    Clinical and epidemiological research: Extended report: The fibrin-derived citrullinated peptide β60–74Cit60,72,74 bears the major ACPA epitope recognised by the rheumatoid arthritis-specific anticitrullinated fibrinogen autoantibodies and anti-CCP2 antibodies
    • M Cornillet,
    • M Sebbag,
    • E Verrouil,
    • A Magyar,
    • F Babos,
    • A Ruyssen-Witrand,
    • F Hudecz,
    • A Cantagrel,
    • G Serre,
    • L Nogueira
    Ann Rheum Dis Published Online First: 1 May 2013 doi:10.1136/annrheumdis-2012-202868
    Clinical and epidemiological research: Extended report: Whole-body MRI in the assessment of disease activity in juvenile dermatomyositis
    • Clara Malattia,
    • Maria Beatrice Damasio,
    • Annalisa Madeo,
    • Angela Pistorio,
    • Anna Providenti,
    • Silvia Pederzoli,
    • Stefania Viola,
    • Antonella Buoncompagni,
    • Chiara Mattiuz,
    • Agnese Beltramo,
    • Alessandro Consolaro,
    • Angelo Ravelli,
    • Nicolino Ruperto,
    • Paolo Picco,
    • Gian Michele Magnano,
    • Alberto Martini
    Ann Rheum Dis Published Online First: 1 May 2013 doi:10.1136/annrheumdis-2012-202915
    Clinical and epidemiological research: Extended report: Osteitis and synovitis, but not bone erosion, is associated with proteoglycan loss and microstructure damage in the cartilage of patients with rheumatoid arthritis
    • Barbara Herz,
    • Andreas Albrecht,
    • Matthias Englbrecht,
    • Götz H Welsch,
    • Michael Uder,
    • Nina Renner,
    • Philipp Schlechtweg,
    • Dominik Paul,
    • Lars Lauer,
    • Klaus Engelke,
    • Rolf Janka,
    • Jürgen Rech,
    • Georg Schett,
    • Stephanie Finzel
    Ann Rheum Dis Published Online First: 26 April 2013 doi:10.1136/annrheumdis-2012-202850
    Clinical and epidemiological research: Concise report: Efficacy of oral prednisolone in active ankylosing spondylitis: results of a double-blind, randomised, placebo-controlled short-term trial
    • H Haibel,
    • C Fendler,
    • J Listing,
    • J Callhoff,
    • J Braun,
    • J Sieper
    Ann Rheum Dis Published Online First: 26 April 2013 doi:10.1136/annrheumdis-2012-203055
    Clinical and epidemiological research: Extended report: Tumour necrosis factor α blockers are more effective than methotrexate in the inhibition of radiographic joint damage progression among patients with psoriatic arthritis
    • Lihi Eder,
    • Arane Thavaneswaran,
    • Vinod Chandran,
    • Dafna D Gladman
    Ann Rheum Dis Published Online First: 25 April 2013 doi:10.1136/annrheumdis-2012-202959
    Clinical and epidemiological research: Extended report: Thyroxin substitution and the risk of developing rheumatoid arthritis; results from the Swedish population-based EIRA study
    • Camilla Bengtsson,
    • Leonid Padyukov,
    • Henrik Källberg,
    • Saedis Saevarsdottir
    Ann Rheum Dis Published Online First: 23 April 2013 doi:10.1136/annrheumdis-2013-203354
    Clinical and epidemiological research: Extended report: Peg-IFNα/ribavirin/protease inhibitor combination in hepatitis C virus associated mixed cryoglobulinemia vasculitis: results at week 24
    • David Saadoun,
    • M Resche Rigon,
    • V Thibault,
    • M Longuet,
    • S Pol,
    • F Blanc,
    • G Pialoux,
    • A Karras,
    • D Bazin-Karra,
    • C Cazorla,
    • D Vittecoq,
    • L Musset,
    • O Decaux,
    • J M Ziza,
    • O Lambotte,
    • Patrice Cacoub
    Ann Rheum Dis Published Online First: 20 April 2013 doi:10.1136/annrheumdis-2012-202770
    Open Access
    Clinical and epidemiological research: Extended report: Measurement error in the assessment of radiographic progression in rheumatoid arthritis (RA) clinical trials: the smallest detectable change (SDC) revisited
    • V Navarro-Compán,
    • D van der Heijde,
    • Harris A Ahmad,
    • Colin G Miller,
    • R Wolterbeek,
    • R Landewé
    Ann Rheum Dis Published Online First: 20 April 2013 doi:10.1136/annrheumdis-2012-202939
    Clinical and epidemiological research: Extended report: The degree of skin involvement identifies distinct lung disease outcomes and survival in systemic sclerosis
    • Tricia R Cottrell,
    • Robert A Wise,
    • Fredrick M Wigley,
    • Francesco Boin
    Ann Rheum Dis Published Online First: 20 April 2013 doi:10.1136/annrheumdis-2012-202849
    Clinical and epidemiological research: Extended report: Genetic associations to germinal centre formation in primary Sjögren's syndrome
    • Tove Ragna Reksten,
    • Svein Joar Auglænd Johnsen,
    • Malin Viktoria Jonsson,
    • Roald Omdal,
    • Johan G Brun,
    • Elke Theander,
    • Per Eriksson,
    • Marie Wahren-Herlenius,
    • Roland Jonsson,
    • Gunnel Nordmark
    Ann Rheum Dis Published Online First: 20 April 2013 doi:10.1136/annrheumdis-2012-202500
    Clinical and epidemiological research: Extended report: The risk of atrial fibrillation in patients with rheumatoid arthritis
    • Seoyoung C Kim,
    • Jun Liu,
    • Daniel H Solomon
    Ann Rheum Dis Published Online First: 20 April 2013 doi:10.1136/annrheumdis-2013-203343
    Clinical and epidemiological research: Extended report: A non-inferiority trial of an attenuated combination strategy (‘COBRA-light’) compared to the original COBRA strategy: clinical results after 26 weeks
    • Debby den Uyl,
    • Marieke ter Wee,
    • Maarten Boers,
    • Pit Kerstens,
    • Alexandre Voskuyl,
    • Mike Nurmohamed,
    • Hennie Raterman,
    • Dirkjan van Schaardenburg,
    • Nancy van Dillen,
    • Ben Dijkmans,
    • Willem Lems
    Ann Rheum Dis Published Online First: 19 April 2013 doi:10.1136/annrheumdis-2012-202818
    Open Access
    Clinical and epidemiological research: Extended report: Safety profile of protein kinase inhibitors in rheumatoid arthritis: systematic review and meta-analysis
    • Eva Salgado,
    • Jose R Maneiro,
    • Loreto Carmona,
    • Juan J Gomez-Reino
    Ann Rheum Dis Published Online First: 18 April 2013 doi:10.1136/annrheumdis-2012-203116
    Clinical and epidemiological research: Concise report: VCAM-1 serum levels are associated with arthropathy in hereditary haemochromatosis
    • Valerie Nell-Duxneuner,
    • Roland Axmann,
    • Emma Husar-Memmer,
    • Tomáš Dallos,
    • Christian Datz,
    • Andreas Stadlmayr,
    • Elmar Aigner,
    • Matthias Englbrecht,
    • Georg Schett,
    • Jochen Zwerina
    Ann Rheum Dis Published Online First: 18 April 2013 doi:10.1136/annrheumdis-2012-202800
    Clinical and epidemiological research: Extended report: A phase 2 dose-ranging study of subcutaneous tabalumab for the treatment of patients with active rheumatoid arthritis and an inadequate response to methotrexate
    • Mark C Genovese,
    • Eric Lee,
    • Julie Satterwhite,
    • Melissa Veenhuizen,
    • Damon Disch,
    • Pierre-Yves Berclaz,
    • Stephen Myers,
    • Gregory Sides,
    • Olivier Benichou
    Ann Rheum Dis Published Online First: 18 April 2013 doi:10.1136/annrheumdis-2012-202864
    Clinical and epidemiological research: Extended report: Moderate vitamin D deficiency is associated with changes in knee and hip pain in older adults: a 5-year longitudinal study
    • Laura L Laslett,
    • Stephen Quinn,
    • John R Burgess,
    • Venkateswaran Parameswaran,
    • Tania M Winzenberg,
    • Graeme Jones,
    • Changhai Ding
    Ann Rheum Dis Published Online First: 17 April 2013 doi:10.1136/annrheumdis-2012-202831
    Clinical and epidemiological research: Extended report: Genetics of toll like receptor 9 in ANCA associated vasculitides
    • C A Husmann,
    • J U Holle,
    • F Moosig,
    • S Mueller,
    • B Wilde,
    • J W Cohen Tervaert,
    • L Harper,
    • G Assmann,
    • W L Gross,
    • J T Epplen,
    • S Wieczorek
    Ann Rheum Dis Published Online First: 16 April 2013 doi:10.1136/annrheumdis-2012-202803
    Clinical and epidemiological research: Extended report: Performance of the 2010 ACR/EULAR classification criteria for rheumatoid arthritis: a systematic literature review
    • Helga Radner,
    • Tuhina Neogi,
    • Josef S Smolen,
    • Daniel Aletaha
    Ann Rheum Dis Published Online First: 16 April 2013 doi:10.1136/annrheumdis-2013-203284
    Clinical and epidemiological research: Extended report: Effect of bisphosphonate use in patients with symptomatic and radiographic knee osteoarthritis: data from the Osteoarthritis Initiative
    • Laura L Laslett,
    • Sarah R Kingsbury,
    • Elizabeth M A Hensor,
    • Michael A Bowes,
    • Philip G Conaghan
    Ann Rheum Dis Published Online First: 12 April 2013 doi:10.1136/annrheumdis-2012-202989
    Clinical and epidemiological research: Extended report: The relationship between longitudinal serum leptin measures and measures of magnetic resonance imaging-assessed knee joint damage in a population of mid-life women
    • Carrie A Karvonen-Gutierrez,
    • Siobán D Harlow,
    • Jon Jacobson,
    • Peter Mancuso,
    • Yebin Jiang
    Ann Rheum Dis Published Online First: 10 April 2013 doi:10.1136/annrheumdis-2012-202685
    Clinical and epidemiological research: Concise report: Relationship between air pollution and positivity of RA-related autoantibodies in individuals without established RA: a report on SERA
    • Ryan W Gan,
    • Kevin D Deane,
    • Gary O Zerbe,
    • M Kristen Demoruelle,
    • Michael H Weisman,
    • Jane H Buckner,
    • Peter K Gregersen,
    • Ted R Mikuls,
    • James R O'Dell,
    • Richard M Keating,
    • V Michael Holers,
    • Jill M Norris
    Ann Rheum Dis Published Online First: 9 April 2013 doi:10.1136/annrheumdis-2012-202949
    Clinical and epidemiological research: Extended report: What is the evidence for the presence of a therapeutic window of opportunity in rheumatoid arthritis? A systematic literature review
    • J A B van Nies,
    • A Krabben,
    • J W Schoones,
    • T W J Huizinga,
    • M Kloppenburg,
    • A H M van der Helm-van Mil
    Ann Rheum Dis Published Online First: 9 April 2013 doi:10.1136/annrheumdis-2012-203130
    Clinical and epidemiological research: Concise report: Switching between TNF inhibitors in psoriatic arthritis: data from the NOR-DMARD study
    • Karen Minde Fagerli,
    • Elisabeth Lie,
    • Désirée van der Heijde,
    • Marte Schrumpf Heiberg,
    • Synøve Kalstad,
    • Erik Rødevand,
    • Knut Mikkelsen,
    • Åse Stavland Lexberg,
    • Tore K Kvien
    Ann Rheum Dis Published Online First: 5 April 2013 doi:10.1136/annrheumdis-2012-203018
    Clinical and epidemiological research: Extended report: Association between testosterone levels and risk of future rheumatoid arthritis in men: a population-based case–control study
    • Mitra Pikwer,
    • Aleksander Giwercman,
    • Ulf Bergström,
    • Jan-Åke Nilsson,
    • Lennart T H Jacobsson,
    • Carl Turesson
    Ann Rheum Dis Published Online First: 3 April 2013 doi:10.1136/annrheumdis-2012-202781
    Press Release
    Clinical and epidemiological research: Concise report: Extent and distribution of CPP deposits in patients affected by calcium pyrophosphate dihydrate deposition disease: an ultrasonographic study
    • Georgios Filippou,
    • Emilio Filippucci,
    • Marika Tardella,
    • Ilaria Bertoldi,
    • Marco Di Carlo,
    • Antonella Adinolfi,
    • Walter Grassi,
    • Bruno Frediani
    Ann Rheum Dis Published Online First: 26 March 2013 doi:10.1136/annrheumdis-2012-202748
    Clinical and epidemiological research: Extended report: Improvements in health-related quality of life with belimumab, a B-lymphocyte stimulator-specific inhibitor, in patients with autoantibody-positive systemic lupus erythematosus from the randomised controlled BLISS trials
    • Vibeke Strand,
    • Roger A Levy,
    • Ricard Cervera,
    • Michelle A Petri,
    • Helen Birch,
    • William W Freimuth,
    • Z John Zhong,
    • Ann E Clarke
    Ann Rheum Dis Published Online First: 22 March 2013 doi:10.1136/annrheumdis-2012-202865
    Open Access
    Clinical and epidemiological research: Extended report: Bone loss before the clinical onset of rheumatoid arthritis in subjects with anticitrullinated protein antibodies
    • Arnd Kleyer,
    • Stephanie Finzel,
    • Jürgen Rech,
    • Bernhard Manger,
    • Manuel Krieter,
    • Francesca Faustini,
    • Elisabeth Araujo,
    • Axel J Hueber,
    • Ulrike Harre,
    • Klaus Engelke,
    • Georg Schett
    Ann Rheum Dis Published Online First: 21 March 2013 doi:10.1136/annrheumdis-2012-202958
    Clinical and epidemiological research: Extended report: Predictors of work disability during the first 3 years after diagnosis in a national rheumatoid arthritis inception cohort
    • Tor Olofsson,
    • Ingemar F Petersson,
    • Jonas K Eriksson,
    • Martin Englund,
    • Julia F Simard,
    • Jan-Åke Nilsson,
    • Pierre Geborek,
    • Lennart T H Jacobsson,
    • Johan Askling,
    • Martin Neovius
    Ann Rheum Dis Published Online First: 21 March 2013 doi:10.1136/annrheumdis-2012-202911
    Clinical and epidemiological research: Extended report: N-terminal pro-brain-type natriuretic peptide (NT-pro-BNP) and mortality risk in early inflammatory polyarthritis: results from the Norfolk Arthritis Registry (NOAR)
    • Hoda Mirjafari,
    • Paul Welsh,
    • Suzanne M M Verstappen,
    • Paddy Wilson,
    • Tarnya Marshall,
    • Helena Edlin,
    • Diane Bunn,
    • Jacqueline Chipping,
    • Mark Lunt,
    • Deborah P M Symmons,
    • Naveed Sattar,
    • Ian N Bruce
    Ann Rheum Dis Published Online First: 19 March 2013 doi:10.1136/annrheumdis-2012-202848
    Open Access
    Clinical and epidemiological research: Extended report: Carotid ultrasound is useful for the cardiovascular risk stratification of patients with rheumatoid arthritis: results of a population-based study
    • Alfonso Corrales,
    • Carlos González-Juanatey,
    • María E Peiró,
    • Ricardo Blanco,
    • Javier Llorca,
    • Miguel A González-Gay
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-203101
    Clinical and epidemiological research: Extended report: Smoking, the HLA-DRB1 shared epitope and ACPA fine-specificity in Koreans with rheumatoid arthritis: evidence for more than one pathogenic pathway linking smoking to disease
    • Benjamin A Fisher,
    • So-Young Bang,
    • Muslima Chowdhury,
    • Hye-Soon Lee,
    • Jae-Hoon Kim,
    • Peter Charles,
    • Patrick Venables,
    • Sang-Cheol Bae
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202535
    Clinical and epidemiological research: Extended report: Continuous long-term anti-TNF therapy does not lead to an increase in the rate of new bone formation over 8 years in patients with ankylosing spondylitis
    • Xenofon Baraliakos,
    • Hildrun Haibel,
    • Joachim Listing,
    • Joachim Sieper,
    • Jürgen Braun
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202698
    Clinical and epidemiological research: Extended report: Mortality risk factors associated with familial Mediterranean fever among a cohort of 1.25 million adolescents
    • Gilad Twig,
    • Avi Livneh,
    • Asaf Vivante,
    • Arnon Afek,
    • Ari Shamiss,
    • Estela Derazne,
    • Dorit Tzur,
    • Ilan Ben-Zvi,
    • Amir Tirosh,
    • Micha Barchana,
    • Tamy Shohat,
    • Eliezer Golan,
    • Howard Amital
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202932
    Clinical and epidemiological research: Extended report: Anaemia may add information to standardised disease activity assessment to predict radiographic damage in rheumatoid arthritis: a prospective cohort study
    • Burkhard Möller,
    • Almut Scherer,
    • Frauke Förger,
    • Peter M Villiger,
    • Axel Finckh
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202709
    Open Access
    Clinical and epidemiological research: Extended report: Kinetics of the long-term antibody response after meningococcal C vaccination in patients with juvenile idiopathic arthritis: a retrospective cohort study
    • Susanne P Stoof,
    • Marloes W Heijstek,
    • Karen M Sijssens,
    • Fiona van der Klis,
    • Elisabeth A M Sanders,
    • Peter F M Teunis,
    • Nico M Wulffraat,
    • Guy A M Berbers
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202561
    Clinical and epidemiological research: Extended report: The 158VV Fcgamma receptor 3A genotype is associated with response to rituximab in rheumatoid arthritis: results of an Italian multicentre study
    • Luca Quartuccio,
    • Martina Fabris,
    • Elena Pontarini,
    • Sara Salvin,
    • Alen Zabotti,
    • Maurizio Benucci,
    • Mariangela Manfredi,
    • Domenico Biasi,
    • Viviana Ravagnani,
    • Fabiola Atzeni,
    • Piercarlo Sarzi-Puttini,
    • Pia Morassi,
    • Fabio Fischetti,
    • Paola Tomietto,
    • Laura Bazzichi,
    • Marta Saracco,
    • Raffaele Pellerito,
    • Marco Cimmino,
    • Franco Schiavon,
    • Valeria Carraro,
    • Angelo Semeraro,
    • Roberto Caporali,
    • Lorenzo Cavagna,
    • Roberto Bortolotti,
    • Giuseppe Paolazzi,
    • Marcello Govoni,
    • Stefano Bombardieri,
    • Salvatore De Vita
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202435
    Clinical and epidemiological research: Extended report: Genome-wide DNA methylation analysis of articular chondrocytes reveals a cluster of osteoarthritic patients
    • Juan Fernández-Tajes,
    • Angel Soto-Hermida,
    • Maria E Vázquez-Mosquera,
    • Estefania Cortés-Pereira,
    • Alejandro Mosquera,
    • Mercedes Fernández-Moreno,
    • Natividad Oreiro,
    • Carlos Fernández-López,
    • Jose Luis Fernández,
    • Ignacio Rego-Pérez,
    • Francisco J Blanco
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202783
    Clinical and epidemiological research: Extended report: Using lifestyle factors to identify individuals at higher risk of inflammatory polyarthritis (results from the European Prospective Investigation of Cancer-Norfolk and the Norfolk Arthritis Register—the EPIC-2-NOAR Study)
    • Manjari Lahiri,
    • Robert N Luben,
    • Catharine Morgan,
    • Diane K Bunn,
    • Tarnya Marshall,
    • Mark Lunt,
    • Suzanne M M Verstappen,
    • Deborah P M Symmons,
    • Kay-Tee Khaw,
    • Nick Wareham,
    • Ian N Bruce
    Ann Rheum Dis Published Online First: 16 March 2013 doi:10.1136/annrheumdis-2012-202481
    Open Access
    Clinical and epidemiological research: Extended report: Open-label tofacitinib and double-blind atorvastatin in rheumatoid arthritis patients: a randomised study*
    • Iain B McInnes,
    • Ho-Youn Kim,
    • Sang-Heon Lee,
    • David Mandel,
    • Yeong-Wook Song,
    • Carol A Connell,
    • Zhen Luo,
    • M Julia Brosnan,
    • Andrea Zuckerman,
    • Samuel H Zwillich,
    • John D Bradley
    Ann Rheum Dis Published Online First: 12 March 2013 doi:10.1136/annrheumdis-2012-202442
    Clinical and epidemiological research: Extended report: Efficacy and safety of adalimumab in Chinese adults with active ankylosing spondylitis: results of a randomised, controlled trial
    • Feng Huang,
    • Jieruo Gu,
    • Ping Zhu,
    • Chunde Bao,
    • Jianhua Xu,
    • Huji Xu,
    • Huaxiang Wu,
    • Guochun Wang,
    • Qun Shi,
    • Nupun Andhivarothai,
    • Jaclyn Anderson,
    • Aileen L Pangan
    Ann Rheum Dis Published Online First: 8 March 2013 doi:10.1136/annrheumdis-2012-202533
    Clinical and epidemiological research: Extended report: Ultrasound colour Doppler is associated with synovial pathology in biopsies from hand joints in rheumatoid arthritis patients: a cross-sectional study
    • Martin Andersen,
    • Karen Ellegaard,
    • Josephine B Hebsgaard,
    • Robin Christensen,
    • Søren Torp-Pedersen,
    • Peter H Kvist,
    • Niels Søe,
    • John Rømer,
    • Nina Vendel,
    • Else Marie Bartels,
    • Bente Danneskiold-Samsøe,
    • Henning Bliddal
    Ann Rheum Dis Published Online First: 8 March 2013 doi:10.1136/annrheumdis-2012-202669
    Clinical and epidemiological research: Extended report: Inequities in access to biologic and synthetic DMARDs across 46 European countries
    • Polina Putrik,
    • Sofia Ramiro,
    • Tore K Kvien,
    • Tuulikki Sokka,
    • Milena Pavlova,
    • Till Uhlig,
    • Annelies Boonen,
    • Working Group ‘Equity in access to treatment of rheumatoid arthritis in Europe’
    Ann Rheum Dis Published Online First: 6 March 2013 doi:10.1136/annrheumdis-2012-202603
    Press Release
    Clinical and epidemiological research: Extended report: Results from a multicentre international registry of familial Mediterranean fever: impact of environment on the expression of a monogenic disease in children
    • Seza Ozen,
    • Erkan Demirkaya,
    • Gayane Amaryan,
    • Isabelle Koné-Paut,
    • Adem Polat,
    • Pat Woo,
    • Yosef Uziel,
    • Consuelo Modesto,
    • Martina Finetti,
    • Pierre Quartier,
    • Efimia Papadopoulou-Alataki,
    • Sulaiman M Al-Mayouf,
    • Giovanna Fabio,
    • Romina Gallizzi,
    • Luca Cantarini,
    • Joost Frenkel,
    • Susan Nielsen,
    • Michael Hofer,
    • Antonella Insalaco,
    • C Acikel,
    • Huri Ozdogan,
    • Alberto Martini,
    • Nicolino Ruperto,
    • Marco Gattorno
    Ann Rheum Dis Published Online First: 5 March 2013 doi:10.1136/annrheumdis-2012-202708
    Clinical and epidemiological research: Extended report: Adalimumab added to a treat-to-target strategy with methotrexate and intra-articular triamcinolone in early rheumatoid arthritis increased remission rates, function and quality of life. The OPERA Study: an investigator-initiated, randomised, double-blind, parallel-group, placebo-controlled trial
    • Kim Hørslev-Petersen,
    • Merete Lund Hetland,
    • Peter Junker,
    • Jan Pødenphant,
    • Torkell Ellingsen,
    • Palle Ahlquist,
    • Hanne Lindegaard,
    • Asta Linauskas,
    • Annette Schlemmer,
    • Mette Yde Dam,
    • Ib Hansen,
    • Hans Christian Horn,
    • Christian Gytz Ammitzbøll,
    • Anette Jørgensen,
    • Sophine B Krintel,
    • Johnny Raun,
    • Julia S Johansen,
    • Mikkel Østergaard,
    • Kristian Stengaard-Pedersen
    Ann Rheum Dis Published Online First: 23 February 2013 doi:10.1136/annrheumdis-2012-202735
    Clinical and epidemiological research: Extended report: Clustering of hand osteoarthritis progression and its relationship to progression of osteoarthritis at the knee
    • Jessica Bijsterbosch,
    • Ingrid Meulenbelt,
    • Iain Watt,
    • Frits R Rosendaal,
    • Tom W J Huizinga,
    • Margreet Kloppenburg
    Ann Rheum Dis Published Online First: 23 February 2013 doi:10.1136/annrheumdis-2012-202461
    Clinical and epidemiological research: Extended report: The autoantibody repertoire in periodontitis: a role in the induction of autoimmunity to citrullinated proteins in rheumatoid arthritis?
    • Paola de Pablo,
    • Thomas Dietrich,
    • Iain L C Chapple,
    • Michael Milward,
    • Muslima Chowdhury,
    • Peter J Charles,
    • Christopher D Buckley,
    • Patrick J Venables
    Ann Rheum Dis Published Online First: 23 February 2013 doi:10.1136/annrheumdis-2012-202701
    Clinical and epidemiological research: Extended report: Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein
    • Stacy P Ardoin,
    • Laura Eve Schanberg,
    • Christy I Sandborg,
    • Huiman X Barnhart,
    • Greg W Evans,
    • Eric Yow,
    • Kelly L Mieszkalski,
    • Norman T Ilowite,
    • Anne Eberhard,
    • Lisa F Imundo,
    • Yuki Kimura,
    • Deborah Levy,
    • Emily von Scheven,
    • Earl Silverman,
    • Suzanne L Bowyer,
    • L Punaro,
    • Nora G Singer,
    • David D Sherry,
    • Deborah K McCurdy,
    • Marissa Klein-Gitelman,
    • Carol Wallace,
    • Richard M Silver,
    • Linda Wagner-Weiner,
    • Gloria C Higgins,
    • Hermine I Brunner,
    • Lawrence Jung,
    • Jennifer B Soep,
    • Ann M Reed,
    • Susan D Thompson
    Ann Rheum Dis Published Online First: 22 February 2013 doi:10.1136/annrheumdis-2012-202315
    Clinical and epidemiological research: Concise report: Phosphodiesterase-5 inhibitors for the treatment of secondary Raynaud's phenomenon: systematic review and meta-analysis of randomised trials
    • Matthieu Roustit,
    • Sophie Blaise,
    • Yannick Allanore,
    • Patrick H Carpentier,
    • Evren Caglayan,
    • Jean-Luc Cracowski
    Ann Rheum Dis Published Online First: 20 February 2013 doi:10.1136/annrheumdis-2012-202836
    Clinical and epidemiological research: Extended report: Patients with non-Jo-1 anti-tRNA-synthetase autoantibodies have worse survival than Jo-1 positive patients
    • Rohit Aggarwal,
    • Elaine Cassidy,
    • Noreen Fertig,
    • Diane Carol Koontz,
    • Mary Lucas,
    • Dana P Ascherman,
    • Chester V Oddis
    Ann Rheum Dis Published Online First: 19 February 2013 doi:10.1136/annrheumdis-2012-201800
    Clinical and epidemiological research: Extended report: Measurement invariance of the Illness Invalidation Inventory (3*I) across language, rheumatic disease and gender
    • Marianne Belia Kool,
    • Rens van de Schoot,
    • Isabel López-Chicheri García,
    • Ricarda Mewes,
    • José A P Da Silva,
    • Karoline Vangronsveld,
    • Andreas A J Wismeijer,
    • Mark A Lumley,
    • Henriët van Middendorp,
    • Johannes W J Bijlsma,
    • Geert Crombez,
    • Winfried Rief,
    • Rinie Geenen
    Ann Rheum Dis Published Online First: 14 February 2013 doi:10.1136/annrheumdis-2012-201807
    Clinical and epidemiological research: Concise report: The multifaceted clinical presentations and manifestations of Erdheim–Chester disease: comprehensive review of the literature and of 10 new cases
    • Giulio Cavalli,
    • Barbara Guglielmi,
    • Alvise Berti,
    • Corrado Campochiaro,
    • Maria Grazia Sabbadini,
    • Lorenzo Dagna
    Ann Rheum Dis Published Online First: 8 February 2013 doi:10.1136/annrheumdis-2012-202542
    Clinical and epidemiological research: Extended report: Shared care or nursing consultations as an alternative to rheumatologist follow-up for rheumatoid arthritis outpatients with low disease activity—patient outcomes from a 2-year, randomised controlled trial
    • Jette Primdahl,
    • Jan Sørensen,
    • Hans Christian Horn,
    • Randi Petersen,
    • Kim Hørslev-Petersen
    Ann Rheum Dis Published Online First: 5 February 2013 doi:10.1136/annrheumdis-2012-202695
    Clinical and epidemiological research: Concise report: Predictors of preterm birth in patients with mild systemic lupus erythematosus
    • Megan E B Clowse,
    • Daniel J Wallace,
    • Michael Weisman,
    • Andra James,
    • Lisa G Criscione-Schreiber,
    • David S Pisetsky
    Ann Rheum Dis Published Online First: 29 January 2013 doi:10.1136/annrheumdis-2012-202449
    Clinical and epidemiological research: Extended report: Efficacy and safety of secukinumab, a fully human anti-interleukin-17A monoclonal antibody, in patients with moderate-to-severe psoriatic arthritis: a 24-week, randomised, double-blind, placebo-controlled, phase II proof-of-concept trial
    • Iain B McInnes,
    • Joachim Sieper,
    • Jürgen Braun,
    • Paul Emery,
    • Désirée van der Heijde,
    • John D Isaacs,
    • Georg Dahmen,
    • Jürgen Wollenhaupt,
    • Hendrik Schulze-Koops,
    • Joseph Kogan,
    • Shenglin Ma,
    • Martin M Schumacher,
    • Arthur P Bertolino,
    • Wolfgang Hueber,
    • Paul P Tak
    Ann Rheum Dis Published Online First: 29 January 2013 doi:10.1136/annrheumdis-2012-202646
    Clinical and epidemiological research: Concise report: The genetic contribution to severe post-traumatic osteoarthritis
    • Ana M Valdes,
    • Sally A Doherty,
    • Kenneth R Muir,
    • Margaret Wheeler,
    • Rose A Maciewicz,
    • Weiya Zhang,
    • Michael Doherty
    Ann Rheum Dis Published Online First: 26 January 2013 doi:10.1136/annrheumdis-2012-202562
    Open Access
    Clinical and epidemiological research: Extended report: Effect of tumour necrosis factor blockers on radiographic progression of psoriatic arthritis: a systematic review and meta-analysis of randomised controlled trials
    • Radjiv Goulabchand,
    • Gaël Mouterde,
    • Thomas Barnetche,
    • Cédric Lukas,
    • Jacques Morel,
    • Bernard Combe
    Ann Rheum Dis Published Online First: 25 January 2013 doi:10.1136/annrheumdis-2012-202641
    Clinical and epidemiological research: Extended report: Early psoriatic arthritis: short symptom duration, male gender and preserved physical functioning at presentation predict favourable outcome at 5-year follow-up. Results from the Swedish Early Psoriatic Arthritis Register (SwePsA)
    • Elke Theander,
    • Tomas Husmark,
    • Gerd-Marie Alenius,
    • Per T Larsson,
    • Annika Teleman,
    • Mats Geijer,
    • Ulla R C Lindqvist
    Ann Rheum Dis Published Online First: 25 January 2013 doi:10.1136/annrheumdis-2012-201972
    Clinical and epidemiological research: Extended report: The characterisation and determinants of quality of life in ANCA associated vasculitis
    • Neil Basu,
    • Andrew McClean,
    • Lorraine Harper,
    • Esther Nicole Amft,
    • Neeraj Dhaun,
    • Raashid A Luqmani,
    • Mark A Little,
    • David RW Jayne,
    • Oliver Flossmann,
    • John McLaren,
    • Vinod Kumar,
    • Lars P Erwig,
    • David M Reid,
    • Gareth T Jones,
    • Gary J Macfarlane
    Ann Rheum Dis Published Online First: 25 January 2013 doi:10.1136/annrheumdis-2012-202750
    Clinical and epidemiological research: Extended report: Expert consensus for performing right heart catheterisation for suspected pulmonary arterial hypertension in systemic sclerosis: a Delphi consensus study with cluster analysis
    • Jérôme Avouac,
    • Dörte Huscher,
    • Daniel E Furst,
    • Christian F Opitz,
    • Oliver Distler,
    • Yannick Allanore
    Ann Rheum Dis Published Online First: 24 January 2013 doi:10.1136/annrheumdis-2012-202567
    Clinical and epidemiological research: Extended report: Metric properties of advanced imaging methods in osteoarthritis of the hand: a systematic review
    • Michael S Saltzherr,
    • Ruud W Selles,
    • Sita M A Bierma-Zeinstra,
    • Galied S R Muradin,
    • J Henk Coert,
    • Johan W van Neck,
    • Jolanda J Luime
    Ann Rheum Dis Published Online First: 24 January 2013 doi:10.1136/annrheumdis-2012-202515
    Clinical and epidemiological research: Extended report: Chronological reading of radiographs in rheumatoid arthritis increases efficiency and does not lead to bias
    • Lilian H D van Tuyl,
    • Désirée van der Heijde,
    • Dirk L Knol,
    • Maarten Boers
    Ann Rheum Dis Published Online First: 24 January 2013 doi:10.1136/annrheumdis-2012-202876
    Clinical and epidemiological research: Concise report: Pneumococcal polysaccharide vaccination in rheumatoid arthritis patients receiving tocilizumab therapy
    • Shunsuke Mori,
    • Yukitaka Ueki,
    • Yukihiro Akeda,
    • Naoyuki Hirakata,
    • Motohiro Oribe,
    • Yoshiki Shiohira,
    • Toshihiko Hidaka,
    • Kazunori Oishi
    Ann Rheum Dis Published Online First: 23 January 2013 doi:10.1136/annrheumdis-2012-202658
    Open Access
    Clinical and epidemiological research: Extended report: Randomised, controlled trial of avocado–soybean unsaponifiable (Piascledine) effect on structure modification in hip osteoarthritis: the ERADIAS study
    • Emmanuel Maheu,
    • Christian Cadet,
    • Marc Marty,
    • Dominique Moyse,
    • Isabelle Kerloch,
    • Philippe Coste,
    • Maxime Dougados,
    • Bernard Mazières,
    • Tim D Spector,
    • Hafid Halhol,
    • Jean-Marie Grouin,
    • Michel Lequesne
    Ann Rheum Dis Published Online First: 23 January 2013 doi:10.1136/annrheumdis-2012-202485
    Open Access
    Clinical and epidemiological research: Extended report: International comparisons of the consultation prevalence of musculoskeletal conditions using population-based healthcare data from England and Sweden
    • Kelvin P Jordan,
    • Anna Jöud,
    • Charlotte Bergknut,
    • Peter Croft,
    • John J Edwards,
    • George Peat,
    • Ingemar F Petersson,
    • Aleksandra Turkiewicz,
    • Ross Wilkie,
    • Martin Englund
    Ann Rheum Dis Published Online First: 23 January 2013 doi:10.1136/annrheumdis-2012-202634
    Open Access
    Clinical and epidemiological research: Extended report: Validation of the systemic lupus erythematosus responder index for use in juvenile-onset systemic lupus erythematosus
    • Rina Mina,
    • Marisa S Klein-Gitelman,
    • Shannen Nelson,
    • B Anne Eberhard,
    • Gloria Higgins,
    • Nora G Singer,
    • Karen Onel,
    • Lori Tucker,
    • Kathleen M O'Neil,
    • Marilynn Punaro,
    • Deborah M Levy,
    • Kathleen Haines,
    • Alberto Martini,
    • Nicolino Ruperto,
    • Daniel Lovell,
    • Hermine I Brunner
    Ann Rheum Dis Published Online First: 23 January 2013 doi:10.1136/annrheumdis-2012-202376
    Clinical and epidemiological research: Extended report: Quantitative measurement of syndesmophyte volume and height in ankylosing spondylitis using CT
    • Sovira Tan,
    • Jianhua Yao,
    • John A Flynn,
    • Lawrence Yao,
    • Michael M Ward
    Ann Rheum Dis Published Online First: 23 January 2013 doi:10.1136/annrheumdis-2012-202661
    Clinical and epidemiological research: Extended report: Low-dose aspirin use and recurrent gout attacks
    • Yuqing Zhang,
    • Tuhina Neogi,
    • Clara Chen,
    • Christine Chaisson,
    • David J Hunter,
    • Hyon Choi
    Ann Rheum Dis Published Online First: 23 January 2013 doi:10.1136/annrheumdis-2012-202589
    Clinical and epidemiological research: Extended report: Five-year outcomes of probable rheumatoid arthritis treated with methotrexate or placebo during the first year (the PROMPT study)
    • Jill van Aken,
    • Lotte Heimans,
    • Henrike Gillet-van Dongen,
    • Karen Visser,
    • H Karel Ronday,
    • Irene Speyer,
    • André J Peeters,
    • Tom W J Huizinga,
    • Cornelia F Allaart
    Ann Rheum Dis Published Online First: 19 January 2013 doi:10.1136/annrheumdis-2012-202967
    Clinical and epidemiological research: Concise report: MRI of hand and foot joints of patients with anticitrullinated peptide antibody positive arthralgia without clinical arthritis
    • Annemarie Krabben,
    • Wouter Stomp,
    • Désirée M F M van der Heijde,
    • Jessica A B van Nies,
    • Johan L Bloem,
    • Tom W J Huizinga,
    • Monique Reijnierse,
    • Annette H M van der Helm-van Mil
    Ann Rheum Dis Published Online First: 19 January 2013 doi:10.1136/annrheumdis-2012-202628
    Clinical and epidemiological research: Concise report: Tendon involvement in the feet of patients with gout: a dual-energy CT study
    • Nicola Dalbeth,
    • Ramanamma Kalluru,
    • Opetaia Aati,
    • Anne Horne,
    • Anthony J Doyle,
    • Fiona M McQueen
    Ann Rheum Dis Published Online First: 19 January 2013 doi:10.1136/annrheumdis-2012-202786
    Clinical and epidemiological research: Extended report: Efficacy and safety of epratuzumab in patients with moderate/severe active systemic lupus erythematosus: results from EMBLEM, a phase IIb, randomised, double-blind, placebo-controlled, multicentre study
    • Daniel J Wallace,
    • Kenneth Kalunian,
    • Michelle A Petri,
    • Vibeke Strand,
    • Frederic A Houssiau,
    • Marilyn Pike,
    • Brian Kilgallen,
    • Sabine Bongardt,
    • Anna Barry,
    • Lexy Kelley,
    • Caroline Gordon
    Ann Rheum Dis Published Online First: 12 January 2013 doi:10.1136/annrheumdis-2012-202760
    Open Access
    Clinical and epidemiological research: Extended report: Tophaceous gout and high level of hyperuricaemia are both associated with increased risk of mortality in patients with gout
    • Fernando Perez-Ruiz,
    • Lorea Martínez-Indart,
    • Loreto Carmona,
    • Ana Maria Herrero-Beites,
    • Jose Ignacio Pijoan,
    • Eswar Krishnan
    Ann Rheum Dis Published Online First: 12 January 2013 doi:10.1136/annrheumdis-2012-202421
    Clinical and epidemiological research: Extended report: Adalimumab, a human anti-TNF monoclonal antibody, outcome study for the prevention of joint damage in Japanese patients with early rheumatoid arthritis: the HOPEFUL 1 study
    • Tsutomu Takeuchi,
    • Hisashi Yamanaka,
    • Naoki Ishiguro,
    • Nobuyuki Miyasaka,
    • Masaya Mukai,
    • Tsukasa Matsubara,
    • Shoji Uchida,
    • Hideto Akama,
    • Hartmut Kupper,
    • Vipin Arora,
    • Yoshiya Tanaka
    Ann Rheum Dis Published Online First: 11 January 2013 doi:10.1136/annrheumdis-2012-202433
    Open Access
    Clinical and epidemiological research: Extended Report: Lymphoma risk in systemic lupus: effects of disease activity versus treatment
    • Sasha Bernatsky,
    • Rosalind Ramsey-Goldman,
    • Lawrence Joseph,
    • Jean-Francois Boivin,
    • Karen H Costenbader,
    • Murray B Urowitz,
    • Dafna D Gladman,
    • Paul R Fortin,
    • Ola Nived,
    • Michelle A Petri,
    • Soren Jacobsen,
    • Susan Manzi,
    • Ellen M Ginzler,
    • David Isenberg,
    • Anisur Rahman,
    • Caroline Gordon,
    • Guillermo Ruiz-Irastorza,
    • Edward Yelin,
    • Sang-Cheol Bae,
    • Daniel J Wallace,
    • Christine A Peschken,
    • Mary Anne Dooley,
    • Steven M Edworthy,
    • Cynthia Aranow,
    • Diane L Kamen,
    • Juanita Romero-Diaz,
    • Anca Askanase,
    • Torsten Witte,
    • Susan G Barr,
    • Lindsey A Criswell,
    • Gunnar K Sturfelt,
    • Irene Blanco,
    • Candace H Feldman,
    • Lene Dreyer,
    • Neha M Patel,
    • Yvan St Pierre,
    • Ann E Clarke
    Ann Rheum Dis Published Online First: 8 January 2013 doi:10.1136/annrheumdis-2012-202099
    Clinical and epidemiological research: Extended report: Effects of golimumab, an anti-tumour necrosis factor-α human monoclonal antibody, on lipids and markers of inflammation
    • Bruce W Kirkham,
    • Mary Chester Wasko,
    • Elizabeth C Hsia,
    • Roy M Fleischmann,
    • Mark C Genovese,
    • Eric L Matteson,
    • Hongjuan Liu,
    • Mahboob U Rahman
    Ann Rheum Dis Published Online First: 7 January 2013 doi:10.1136/annrheumdis-2012-202089
    Open Access
    Clinical and epidemiological research: Extended report: The role of methotrexate co-medication in TNF-inhibitor treatment in patients with psoriatic arthritis: results from 440 patients included in the NOR-DMARD study
    • Karen Minde Fagerli,
    • Elisabeth Lie,
    • Désirée van der Heijde,
    • Marte Schrumpf Heiberg,
    • Åse Stavland Lexberg,
    • Eric Rødevand,
    • Synøve Kalstad,
    • Knut Mikkelsen,
    • Tore K Kvien
    Ann Rheum Dis Published Online First: 3 January 2013 doi:10.1136/annrheumdis-2012-202347
    Clinical and epidemiological research: Concise report: Smoking and delay to diagnosis are associated with poorer functional outcome in psoriatic arthritis
    • William Tillett,
    • Deepak Jadon,
    • Gavin Shaddick,
    • Charlotte Cavill,
    • Eleanor Korendowych,
    • Corinne S de Vries,
    • Neil McHugh
    Ann Rheum Dis Published Online First: 3 January 2013 doi:10.1136/annrheumdis-2012-202608
    Clinical and epidemiological research: Extended report: Tabalumab, an anti-BAFF monoclonal antibody, in patients with active rheumatoid arthritis with an inadequate response to TNF inhibitors
    • Mark C Genovese,
    • Roy M Fleischmann,
    • Maria Greenwald,
    • Julie Satterwhite,
    • Melissa Veenhuizen,
    • Li Xie,
    • Pierre-Yves Berclaz,
    • Stephen Myers,
    • Olivier Benichou
    Ann Rheum Dis Published Online First: 25 December 2012 doi:10.1136/annrheumdis-2012-202775
    Clinical and epidemiological research: Extended report: A multi-centre, blinded, randomised, placebo-controlled, laboratory-based study of MQX-503, a novel topical gel formulation of nitroglycerine, in patients with Raynaud phenomenon
    • Laura K Hummers,
    • Carin E Dugowson,
    • Frederick J Dechow,
    • Robert A Wise,
    • Jeffrey Gregory,
    • Joel Michalek,
    • Gayane Yenokyan,
    • John McGready,
    • Fredrick M Wigley
    Ann Rheum Dis Published Online First: 25 December 2012 doi:10.1136/annrheumdis-2012-201536
    Clinical and epidemiological research: Extended report: MicroRNA-146a and Ets-1 gene polymorphisms in ocular Behçet's disease and Vogt–Koyanagi–Harada syndrome
    • Qingyun Zhou,
    • Shengping Hou,
    • Liang Liang,
    • Xinyu Li,
    • Xiaoyu Tan,
    • Lin Wei,
    • Bo Lei,
    • Aize Kijlstra,
    • Peizeng Yang
    Ann Rheum Dis Published Online First: 25 December 2012 doi:10.1136/annrheumdis-2012-201627
    Clinical and epidemiological research: Extended report: Should I send my patient with previous giant cell arteritis for imaging of the thoracic aorta? A systematic literature review and meta-analysis
    • Sarah Louise Mackie,
    • Elizabeth M A Hensor,
    • Ann W Morgan,
    • Colin T Pease
    Ann Rheum Dis Published Online First: 22 December 2012 doi:10.1136/annrheumdis-2012-202145
    Clinical and epidemiological research: Concise report: Female patients with ankylosing spondylitis: analysis of the impact of gender across treatment studies
    • Irene E van der Horst-Bruinsma,
    • Debra Jeske Zack,
    • Annette Szumski,
    • Andrew S Koenig
    Ann Rheum Dis Published Online First: 22 December 2012 doi:10.1136/annrheumdis-2012-202431
    Clinical and epidemiological research: Extended report: Treatment to lipid targets in patients with inflammatory joint diseases in a preventive cardio-rheuma clinic
    • Silvia Rollefstad,
    • Tore K Kvien,
    • Ingar Holme,
    • Anne S Eirheim,
    • Terje R Pedersen,
    • Anne Grete P Semb
    Ann Rheum Dis Published Online First: 22 December 2012 doi:10.1136/annrheumdis-2012-202789
    Clinical and epidemiological research: Extended report: Risk of mortality in patients with psoriatic arthritis, rheumatoid arthritis and psoriasis: a longitudinal cohort study
    • Alexis Ogdie,
    • Kevin Haynes,
    • Andrea B Troxel,
    • Thorvardur Jon Love,
    • Sean Hennessy,
    • Hyon Choi,
    • Joel M Gelfand
    Ann Rheum Dis Published Online First: 21 December 2012 doi:10.1136/annrheumdis-2012-202424
    Clinical and epidemiological research: Extended report: Annual direct medical cost of active systemic lupus erythematosus in five European countries
    • Andrea Doria,
    • Zahir Amoura,
    • Ricard Cervera,
    • Munther A Khamastha,
    • Matthias Schneider,
    • Jutta Richter,
    • Francis Guillemin,
    • Gisela Kobelt,
    • Frédérique Maurel,
    • Anna Garofano,
    • Alessandra Perna,
    • Miranda Murray,
    • Claude Schmitt,
    • Isabelle Boucot
    Ann Rheum Dis Published Online First: 21 December 2012 doi:10.1136/annrheumdis-2012-202443
    Clinical and epidemiological research: Extended report: Circulating maternal cytokines influence fetal growth in pregnant women with rheumatoid arthritis
    • Florentien D O de Steenwinkel,
    • Anita C S Hokken-Koelega,
    • Yaël A de Man,
    • Y B de Rijke,
    • Maria A J de Ridder,
    • Johanna M W Hazes,
    • Radboud J E M Dolhain
    Ann Rheum Dis Published Online First: 21 December 2012 doi:10.1136/annrheumdis-2012-202539
    Clinical and epidemiological research: Extended report: Validity of a three-variable Juvenile Arthritis Disease Activity Score in children with new-onset juvenile idiopathic arthritis
    • Flora Mcerlane,
    • Michael W Beresford,
    • Eileen M Baildam,
    • S E Alice Chieng,
    • Joyce E Davidson,
    • Helen E Foster,
    • Janet Gardner-Medwin,
    • Mark Lunt,
    • Lucy R Wedderburn,
    • Wendy Thomson,
    • Kimme L Hyrich
    Ann Rheum Dis Published Online First: 20 December 2012 doi:10.1136/annrheumdis-2012-202031
    Open Access
    Clinical and epidemiological research: Extended report: Large-vessel involvement in giant cell arteritis: a population-based cohort study of the incidence-trends and prognosis
    • Tanaz A Kermani,
    • Kenneth J Warrington,
    • Cynthia S Crowson,
    • Steven R Ytterberg,
    • Gene G Hunder,
    • Sherine E Gabriel,
    • Eric L Matteson
    Ann Rheum Dis Published Online First: 19 December 2012 doi:10.1136/annrheumdis-2012-202408
    Clinical and epidemiological research: Concise report: Outcomes of patients with systemic sclerosis-associated polyarthritis and myopathy treated with tocilizumab or abatacept: a EUSTAR observational study
    • Muriel Elhai,
    • Marine Meunier,
    • Marco Matucci-Cerinic,
    • Britta Maurer,
    • Gabriela Riemekasten,
    • Tifenn Leturcq,
    • Raffaele Pellerito,
    • Carlos Alberto Von Mühlen,
    • Alessandra Vacca,
    • Paolo Airo,
    • Francesca Bartoli,
    • Ginevra Fiori,
    • Maria Bokarewa,
    • Valeria Riccieri,
    • Mike Becker,
    • Jérôme Avouac,
    • Ulf Müller-Ladner,
    • Oliver Distler,
    • Yannick Allanore
    Ann Rheum Dis Published Online First: 19 December 2012 doi:10.1136/annrheumdis-2012-202657
    Clinical and epidemiological research: Extended report: Comorbid diseases as predictors of survival of primary total hip and knee replacements: a nationwide register-based study of 96 754 operations on patients with primary osteoarthritis
    • Esa Jämsen,
    • Mikko Peltola,
    • Antti Eskelinen,
    • Matti U K Lehto
    Ann Rheum Dis Published Online First: 19 December 2012 doi:10.1136/annrheumdis-2012-202064
    Open Access
    Clinical and epidemiological research: Extended report: Serum adipokines in patients with psoriatic arthritis and psoriasis alone and their correlation with disease activity
    • Lihi Eder,
    • Jai Jayakar,
    • Remy Pollock,
    • Fawnda Pellett,
    • Arane Thavaneswaran,
    • Vinod Chandran,
    • Cheryl F Rosen,
    • Dafna D Gladman
    Ann Rheum Dis Published Online First: 14 December 2012 doi:10.1136/annrheumdis-2012-202325
    Clinical and epidemiological research: Extended report: Efficacy and safety of mavrilimumab in subjects with rheumatoid arthritis
    • Gerd R Burmester,
    • Michael E Weinblatt,
    • Iain B McInnes,
    • Duncan Porter,
    • Olga Barbarash,
    • Mykola Vatutin,
    • Istvan Szombati,
    • Ehsanollah Esfandiari,
    • Matthew A Sleeman,
    • Christopher D Kane,
    • Guy Cavet,
    • Bing Wang,
    • Alex Godwood,
    • Fabio Magrini,
    • for the EARTH Study Group
    Ann Rheum Dis Published Online First: 12 December 2012 doi:10.1136/annrheumdis-2012-202450
    Clinical and epidemiological research: Concise report: Trends in the first decade of 21st century healthcare utilisation in a rheumatoid arthritis cohort compared with the general population
    • Sofia Hagel,
    • Ingemar F Petersson,
    • Ann Bremander,
    • Elisabet Lindqvist,
    • Charlotte Bergknut,
    • Martin Englund
    Ann Rheum Dis Published Online First: 8 December 2012 doi:10.1136/annrheumdis-2012-202571
    Clinical and epidemiological research: Extended report: The immunogenicity of anti-TNF therapy in immune-mediated inflammatory diseases: a systematic review of the literature with a meta-analysis
    • Sandra Garcês,
    • Jocelyne Demengeot,
    • Elizabeth Benito-Garcia
    Ann Rheum Dis Published Online First: 6 December 2012 doi:10.1136/annrheumdis-2012-202220
    Clinical and epidemiological research: Extended report: Ultrasound for diagnosis of carpal tunnel syndrome: comparison of different methods to determine median nerve volume and value of power Doppler sonography
    • Christian Dejaco,
    • Martin Stradner,
    • Dorothea Zauner,
    • Werner Seel,
    • Nicole Elisabeth Simmet,
    • Alexander Klammer,
    • Petra Heitzer,
    • Kerstin Brickmann,
    • Judith Gretler,
    • Florentine C Fürst-Moazedi,
    • Rene Thonhofer,
    • Rusmir Husic,
    • Josef Hermann,
    • Winfried B Graninger,
    • Stefan Quasthoff
    Ann Rheum Dis Published Online First: 4 December 2012 doi:10.1136/annrheumdis-2012-202328
    Clinical and epidemiological research: Extended report: Addition of infliximab compared with addition of sulfasalazine and hydroxychloroquine to methotrexate in early rheumatoid arthritis: 2-year quality-of-life results of the randomised, controlled, SWEFOT trial
    • Johan A Karlsson,
    • Martin Neovius,
    • Jan-Åke Nilsson,
    • Ingemar F Petersson,
    • Johan Bratt,
    • Ronald F van Vollenhoven,
    • Sofia Ernestam,
    • Pierre Geborek
    Ann Rheum Dis Published Online First: 29 November 2012 doi:10.1136/annrheumdis-2012-202062
    Clinical and epidemiological research: Extended report: Construct and criterion validity of several proposed DAS28-based rheumatoid arthritis flare criteria: an OMERACT cohort validation study
    • Aatke van der Maas,
    • Elisabeth Lie,
    • Robin Christensen,
    • Ernest Choy,
    • Yaël A de Man,
    • Piet van Riel,
    • Thasia Woodworth,
    • Alfons A den Broeder
    Ann Rheum Dis Published Online First: 23 November 2012 doi:10.1136/annrheumdis-2012-202281
    Clinical and epidemiological research: Extended report: A prediction rule for the development of arthritis in seropositive arthralgia patients
    • Lotte Arwen van de Stadt,
    • Birgit I Witte,
    • Wouter H Bos,
    • Dirkjan van Schaardenburg
    Ann Rheum Dis Published Online First: 23 November 2012 doi:10.1136/annrheumdis-2012-202127
    Clinical and epidemiological research: Extended report: Lupuzor/P140 peptide in patients with systemic lupus erythematosus: a randomised, double-blind, placebo-controlled phase IIb clinical trial
    • Robert Zimmer,
    • Hugo R Scherbarth,
    • Oscar Luis Rillo,
    • Juan Jesus Gomez-Reino,
    • Sylviane Muller
    Ann Rheum Dis Published Online First: 21 November 2012 doi:10.1136/annrheumdis-2012-202460
    Open Access
    Clinical and epidemiological research: Extended report: Efficacy of biological agents in juvenile idiopathic arthritis: a systematic review using indirect comparisons
    • Marieke H Otten,
    • Janneke Anink,
    • Sandra Spronk,
    • Lisette W A van Suijlekom-Smit
    Ann Rheum Dis Published Online First: 21 November 2012 doi:10.1136/annrheumdis-2012-201991
    Clinical and epidemiological research: Extended report: Clinical efficacy, radiographic and safety findings through 2 years of golimumab treatment in patients with active psoriatic arthritis: results from a long-term extension of the randomised, placebo-controlled GO-REVEAL study
    • Arthur Kavanaugh,
    • Iain B McInnes,
    • Philip J Mease,
    • Gerald G Krueger,
    • Dafna D Gladman,
    • Désirée van der Heijde,
    • Surekha Mudivarthy,
    • Weichun Xu,
    • Michael Mack,
    • Zhenhua Xu,
    • Anna Beutler
    Ann Rheum Dis Published Online First: 17 November 2012 doi:10.1136/annrheumdis-2012-202035
    Open Access
    Clinical and epidemiological research: Extended report: Individualised aerobic and resistance exercise training improves cardiorespiratory fitness and reduces cardiovascular risk in patients with rheumatoid arthritis
    • Antonios Stavropoulos-Kalinoglou,
    • Giorgos S Metsios,
    • Jet JJCS Veldhuijzen van Zanten,
    • Peter Nightingale,
    • George D Kitas,
    • Yiannis Koutedakis
    Ann Rheum Dis Published Online First: 15 November 2012 doi:10.1136/annrheumdis-2012-202075
    Clinical and epidemiological research: Extended report: Long-term work disability in patients with psoriatic arthritis treated with anti-tumour necrosis factor: a population-based regional Swedish cohort study
    • Lars Erik Kristensen,
    • Martin Englund,
    • Martin Neovius,
    • Johan Askling,
    • Lennart T H Jacobsson,
    • Ingemar F Petersson
    Ann Rheum Dis Published Online First: 12 November 2012 doi:10.1136/annrheumdis-2012-202229
    Clinical and epidemiological research: Extended report: Long-term safety of pegloticase in chronic gout refractory to conventional treatment
    • Michael A Becker,
    • Herbert S B Baraf,
    • Robert A Yood,
    • Aileen Dillon,
    • Janitzia Vázquez-Mellado,
    • Faith D Ottery,
    • Dinesh Khanna,
    • John S Sundy
    Ann Rheum Dis Published Online First: 10 November 2012 doi:10.1136/annrheumdis-2012-201795
    Press Release Open Access
    Clinical and epidemiological research: Extended report: Hydroxychloroquine in systemic lupus erythematosus: results of a French multicentre controlled trial (PLUS Study)
    • Nathalie Costedoat-Chalumeau,
    • Lionel Galicier,
    • Olivier Aumaître,
    • Camille Francès,
    • Véronique Le Guern,
    • Frédéric Lioté,
    • Amar Smail,
    • Nicolas Limal,
    • Laurent Perard,
    • Hélène Desmurs-Clavel,
    • Du Le Thi Huong Boutin,
    • Bouchra Asli,
    • Jean-Emmanuel Kahn,
    • Jacques Pourrat,
    • Laurent Sailler,
    • Félix Ackermann,
    • Thomas Papo,
    • Karim Sacré,
    • Olivier Fain,
    • Jerome Stirnemann,
    • Patrice Cacoub,
    • Moez Jallouli,
    • Gaelle Leroux,
    • Judith Cohen-Bittan,
    • Marie-Laure Tanguy,
    • Jean-Sébastien Hulot,
    • Philippe Lechat,
    • Lucile Musset,
    • Zahir Amoura,
    • Jean-Charles Piette
    Ann Rheum Dis Published Online First: 10 November 2012 doi:10.1136/annrheumdis-2012-202322
    Clinical and epidemiological research: Extended report: ASAS modification of the Berlin algorithm for diagnosing axial spondyloarthritis: results from the SPondyloArthritis Caught Early (SPACE)-cohort and from the Assessment of SpondyloArthritis international Society (ASAS)-cohort
    • Rosaline van den Berg,
    • Manouk de Hooge,
    • Martin Rudwaleit,
    • Joachim Sieper,
    • Floris van Gaalen,
    • Monique Reijnierse,
    • Robert Landewé,
    • Tom Huizinga,
    • Désirée van der Heijde
    Ann Rheum Dis Published Online First: 8 November 2012 doi:10.1136/annrheumdis-2012-201884
    Clinical and epidemiological research: Extended report: Efficacy and safety of adalimumab for the treatment of peripheral arthritis in spondyloarthritis patients without ankylosing spondylitis or psoriatic arthritis
    • Jacqueline E Paramarta,
    • Leen De Rycke,
    • Tanja F Heijda,
    • Carmen A Ambarus,
    • Koen Vos,
    • Huib J Dinant,
    • Paul P Tak,
    • Dominique L Baeten
    Ann Rheum Dis Published Online First: 8 November 2012 doi:10.1136/annrheumdis-2012-202245
    Clinical and epidemiological research: Extended report: Long-term safety of rituximab in rheumatoid arthritis: 9.5-year follow-up of the global clinical trial programme with a focus on adverse events of interest in RA patients
    • Ronald F van Vollenhoven,
    • Paul Emery,
    • Clifton O Bingham III,
    • Edward C Keystone,
    • Roy M Fleischmann,
    • Daniel E Furst,
    • Nicola Tyson,
    • Neil Collinson,
    • Patricia B Lehane
    Ann Rheum Dis Published Online First: 7 November 2012 doi:10.1136/annrheumdis-2012-201956
    Open Access
    Clinical and epidemiological research: Extended report: Healthcare service utilisation costs are reduced when rheumatoid arthritis patients achieve sustained remission
    • Cheryl Barnabe,
    • Nguyen Xuan Thanh,
    • Arto Ohinmaa,
    • Joanne Homik,
    • Susan G Barr,
    • Liam Martin,
    • Walter P Maksymowych
    Ann Rheum Dis Published Online First: 1 November 2012 doi:10.1136/annrheumdis-2012-201918
    Clinical and epidemiological research: Extended report: IFNα and its response proteins, IP-10 and SIGLEC-1, are biomarkers of disease activity in systemic lupus erythematosus
    • Thomas Rose,
    • Andreas Grützkau,
    • Heike Hirseland,
    • Dörte Huscher,
    • Cornelia Dähnrich,
    • Andrzej Dzionek,
    • Tobias Ozimkowski,
    • Wolfgang Schlumberger,
    • Philipp Enghard,
    • Andreas Radbruch,
    • Gabriela Riemekasten,
    • Gerd-Rüdiger Burmester,
    • Falk Hiepe,
    • Robert Biesen
    Ann Rheum Dis Published Online First: 31 October 2012 doi:10.1136/annrheumdis-2012-201586
    Clinical and epidemiological research: Extended report: Response to glucocorticoids at 2 weeks predicts the effectiveness of DMARD induction therapy at 3 months: post hoc analyses from the tREACH study
    • Pascal Hendrik Pieter de Jong,
    • Rogier A Quax,
    • Margriet Huisman,
    • A H Gerards,
    • Richard A Feelders,
    • Peter B de Sonnaville,
    • Jolanda J Luime,
    • Angelique E Weel,
    • J M Hazes
    Ann Rheum Dis Published Online First: 31 October 2012 doi:10.1136/annrheumdis-2012-202152
    Clinical and epidemiological research: Extended report: Metabolic health in families enriched for longevity is associated with low prevalence of hand osteoarthritis and influences OA biomarker profiles
    • Steffan Daniël Bos,
    • Marian Beekman,
    • Andrea B Maier,
    • Morton A Karsdal,
    • Wing-Yee Kwok,
    • Anne Christine Bay-Jensen,
    • Margreet Kloppenburg,
    • P Eline Slagboom,
    • Ingrid Meulenbelt
    Ann Rheum Dis Published Online First: 27 October 2012 doi:10.1136/annrheumdis-2012-202013
    Clinical and epidemiological research: Extended report: Smoking and overweight determine the likelihood of developing rheumatoid arthritis
    • Maria J H de Hair,
    • Robert B M Landewé,
    • Marleen G H van de Sande,
    • Dirkjan van Schaardenburg,
    • Lisa G M van Baarsen,
    • Danielle M Gerlag,
    • Paul P Tak
    Ann Rheum Dis Published Online First: 27 October 2012 doi:10.1136/annrheumdis-2012-202254
    Open Access
    Clinical and epidemiological research: Extended report: Therapeutic approaches for the treatment of renal disease in juvenile systemic lupus erythematosus: an international multicentre PRINTO study
    • Paivi M Miettunen,
    • Angela Pistorio,
    • Elena Palmisani,
    • Angelo Ravelli,
    • Earl Silverman,
    • Sheila Oliveira,
    • Maria Alessio,
    • Ruben Cuttica,
    • Dimitrina Mihaylova,
    • Graciela Espada,
    • Srdjan Pasic,
    • Antonella Insalaco,
    • Seza Ozen,
    • Oscar Porras,
    • Flavio Sztajnbok,
    • Dragana Lazarevic,
    • Alberto Martini,
    • Nicolino Ruperto,
    • for the Paediatric Rheumatology International Trials Organisation (PRINTO)
    Ann Rheum Dis Published Online First: 25 October 2012 doi:10.1136/annrheumdis-2012-201937
    Clinical and epidemiological research: Extended report: Disease activity assessment in childhood vasculitis: development and preliminary validation of the Paediatric Vasculitis Activity Score (PVAS)
    • Pavla Dolezalova,
    • Fiona E Price-Kuehne,
    • Seza Özen,
    • Susanne M Benseler,
    • David A Cabral,
    • Jordi Anton,
    • Jürgen Brunner,
    • Rolando Cimaz,
    • Katheleen M O'Neil,
    • Carol A Wallace,
    • Nicholas Wilkinson,
    • Despina Eleftheriou,
    • Erkan Demirkaya,
    • Marek Böhm,
    • Petra Krol,
    • Raashid A Luqmani,
    • Paul A Brogan
    Ann Rheum Dis Published Online First: 25 October 2012 doi:10.1136/annrheumdis-2012-202111
    Clinical and epidemiological research: Extended report: Why the findings of published multiple treatment comparison meta-analyses of biologic treatments for rheumatoid arthritis are different: an overview of recurrent methodological shortcomings
    • Kristian Thorlund,
    • Eric Druyts,
    • J Antonio Aviña-Zubieta,
    • Ping Wu,
    • Edward J Mills
    Ann Rheum Dis Published Online First: 20 October 2012 doi:10.1136/annrheumdis-2012-201574
    Clinical and epidemiological research: Extended report: Sustained efficacy of the monoclonal anti-interleukin-1 beta antibody canakinumab in a 9-month trial in Schnitzler's syndrome
    • Heleen D de Koning,
    • Joost Schalkwijk,
    • Johanna van der Ven-Jongekrijg,
    • Monique Stoffels,
    • Jos W M van der Meer,
    • Anna Simon
    Ann Rheum Dis Published Online First: 19 October 2012 doi:10.1136/annrheumdis-2012-202192
    Clinical and epidemiological research: Extended report: Demographic and disease-related predictors of abnormal lung function in patients with established inflammatory polyarthritis and a comparison with the general population
    • Suzanne M M Verstappen,
    • Mark Lunt,
    • Robert N Luben,
    • Jackie Chipping,
    • Tarnya Marshall,
    • Kay-Tee Khaw,
    • Nick Wareham,
    • William G Dixon,
    • Ian N Bruce,
    • Deborah P M Symmons
    Ann Rheum Dis Published Online First: 13 October 2012 doi:10.1136/annrheumdis-2012-201698
    Open Access
    Clinical and epidemiological research: Extended report: Comparison of two referral strategies for diagnosis of axial spondyloarthritis: the Recognising and Diagnosing Ankylosing Spondylitis Reliably (RADAR) study
    • Joachim Sieper,
    • Shankar Srinivasan,
    • Omid Zamani,
    • Herman Mielants,
    • Denis Choquette,
    • Karel Pavelka,
    • Anne Gitte Loft,
    • Pál Géher,
    • Debashish Danda,
    • Tatiana Reitblat,
    • Fabrizio Cantini,
    • Codrina Ancuta,
    • Shandor Erdes,
    • Helena Raffayová,
    • Andrew Keat,
    • J S H Gaston,
    • Sonja Praprotnik,
    • Nathan Vastesaeger
    Ann Rheum Dis Published Online First: 13 October 2012 doi:10.1136/annrheumdis-2012-201777
    Clinical and epidemiological research: Extended report: Genome-wide association study identifies GIMAP as a novel susceptibility locus for Behçet's disease
    • Yun Jong Lee,
    • Yukihiro Horie,
    • Graham R Wallace,
    • Yong Seok Choi,
    • Ji Ah Park,
    • Ji Yong Choi,
    • Ran Song,
    • Young-Mo Kang,
    • Seong Wook Kang,
    • Han Joo Baek,
    • Nobuyoshi Kitaichi,
    • Akira Meguro,
    • Nobuhisa Mizuki,
    • Kenichi Namba,
    • Susumu Ishida,
    • Jinhyun Kim,
    • Edyta Niemczyk,
    • Eun Young Lee,
    • Yeong Wook Song,
    • Shigeaki Ohno,
    • Eun Bong Lee
    Ann Rheum Dis Published Online First: 6 October 2012 doi:10.1136/annrheumdis-2011-200288
    Clinical and epidemiological research: Extended report: The structural basis of MRI bone erosions: an assessment by microCT
    • Andreas Albrecht,
    • Stephanie Finzel,
    • Matthias Englbrecht,
    • Jürgen Rech,
    • Axel Hueber,
    • Philipp Schlechtweg,
    • Michael Uder,
    • Georg Schett
    Ann Rheum Dis Published Online First: 19 September 2012 doi:10.1136/annrheumdis-2012-201982
    Clinical and epidemiological research: Extended report: Novel genetic variants associated with lumbar disc degeneration in northern Europeans: a meta-analysis of 4600 subjects
    • Frances M K Williams,
    • Aruna T Bansal,
    • Joyce B van Meurs,
    • Jordana T Bell,
    • Ingrid Meulenbelt,
    • Pradeep Suri,
    • Fernando Rivadeneira,
    • Philip N Sambrook,
    • Albert Hofman,
    • Sita Bierma-Zeinstra,
    • Cristina Menni,
    • Margreet Kloppenburg,
    • P Eline Slagboom,
    • David J Hunter,
    • Alex J MacGregor,
    • Andre G Uitterlinden,
    • Tim D Spector
    Ann Rheum Dis Published Online First: 19 September 2012 doi:10.1136/annrheumdis-2012-201551
    Open Access
    Clinical and epidemiological research: Extended report: Increased IL-17A expression in temporal artery lesions is a predictor of sustained response to glucocorticoid treatment in patients with giant-cell arteritis
    • Georgina Espígol-Frigolé,
    • Marc Corbera-Bellalta,
    • Ester Planas-Rigol,
    • Ester Lozano,
    • Marta Segarra,
    • Ana García-Martínez,
    • Sergio Prieto-González,
    • José Hernández-Rodríguez,
    • Josep M Grau,
    • Mahboob U Rahman,
    • Maria C Cid
    Ann Rheum Dis Published Online First: 19 September 2012 doi:10.1136/annrheumdis-2012-201836
    Clinical and epidemiological research: Extended report: Application of the 2010 ACR/EULAR classification criteria in patients with very early inflammatory arthritis: analysis of sensitivity, specificity and predictive values in the SAVE study cohort
    • Iuliia Biliavska,
    • Tanja A Stamm,
    • Jose Martinez-Avila,
    • Thomas W J Huizinga,
    • Robert B M Landewé,
    • Günter Steiner,
    • Daniel Aletaha,
    • Josef S Smolen,
    • Klaus P Machold
    Ann Rheum Dis Published Online First: 15 September 2012 doi:10.1136/annrheumdis-2012-201909
    Open Access
    Clinical and epidemiological research: Extended report: Golimumab monotherapy in Japanese patients with active rheumatoid arthritis despite prior treatment with disease-modifying antirheumatic drugs: results of the phase 2/3, multicentre, randomised, double-blind, placebo-controlled GO-MONO study through 24 weeks
    • Tsutomu Takeuchi,
    • Masayoshi Harigai,
    • Yoshiya Tanaka,
    • Hisashi Yamanaka,
    • Naoki Ishiguro,
    • Kazuhiko Yamamoto,
    • Nobuyuki Miyasaka,
    • Takao Koike,
    • Minoru Kanazawa,
    • Takuya Oba,
    • Toru Yoshinari,
    • Daniel Baker
    Ann Rheum Dis Published Online First: 14 September 2012 doi:10.1136/annrheumdis-2012-201796
    Open Access
    Clinical and epidemiological research: Extended report: Efficacy and safety of apremilast, an oral phosphodiesterase 4 inhibitor, in ankylosing spondylitis
    • Ejaz Pathan,
    • Sonya Abraham,
    • Elizabeth Van Rossen,
    • Robin Withrington,
    • Andrew Keat,
    • Peter J Charles,
    • Erin Paterson,
    • Muslima Chowdhury,
    • Catherine McClinton,
    • Peter C Taylor
    Ann Rheum Dis Published Online First: 14 September 2012 doi:10.1136/annrheumdis-2012-201915
    Clinical and epidemiological research: Extended report: Serum urate association with hypertension in young adults: analysis from the Coronary Artery Risk Development in Young Adults cohort
    • Angelo L Gaffo,
    • David R Jacobs, Jr,
    • Femke Sijtsma,
    • Cora E Lewis,
    • Ted R Mikuls,
    • Kenneth G Saag
    Ann Rheum Dis Published Online First: 14 September 2012 doi:10.1136/annrheumdis-2012-201916
    Clinical and epidemiological research: Extended report: Reliability of a consensus-based ultrasound score for tenosynovitis in rheumatoid arthritis
    • Esperanza Naredo,
    • Maria Antonietta D'Agostino,
    • Richard J Wakefield,
    • Ingrid Möller,
    • Peter V Balint,
    • Emilio Filippucci,
    • Annamaria Iagnocco,
    • Zunaid Karim,
    • Lene Terslev,
    • David A Bong,
    • Jesús Garrido,
    • David Martínez-Hernández,
    • George A W Bruyn
    Ann Rheum Dis Published Online First: 14 September 2012 doi:10.1136/annrheumdis-2012-202092
    Clinical and epidemiological research: Extended report: Serum proteins reflecting inflammation, injury and repair as biomarkers of disease activity in ANCA-associated vasculitis
    • Paul A Monach,
    • Roscoe L Warner,
    • Gunnar Tomasson,
    • Ulrich Specks,
    • John H Stone,
    • Linna Ding,
    • Fernando C Fervenza,
    • Barri J Fessler,
    • Gary S Hoffman,
    • David Iklé,
    • Cees GM Kallenberg,
    • Jeffrey Krischer,
    • Carol A Langford,
    • Mark Mueller,
    • Philip Seo,
    • E William St. Clair,
    • Robert Spiera,
    • Nadia Tchao,
    • Steven R Ytterberg,
    • Kent J Johnson,
    • Peter A Merkel
    Ann Rheum Dis Published Online First: 12 September 2012 doi:10.1136/annrheumdis-2012-201981
    Clinical and epidemiological research: Extended report: The US7 score is sensitive to change in a large cohort of patients with rheumatoid arthritis over 12 months of therapy
    • Tina M Backhaus,
    • Sarah Ohrndorf,
    • Herbert Kellner,
    • Johannes Strunk,
    • Wolfgang Hartung,
    • Horst Sattler,
    • Christof Iking-Konert,
    • Gerd R Burmester,
    • Wolfgang A Schmidt,
    • Marina Backhaus
    Ann Rheum Dis Published Online First: 6 September 2012 doi:10.1136/annrheumdis-2012-201397
    Open Access
    Clinical and epidemiological research: Extended report: Reasons for medical help-seeking behaviour of patients with recent-onset arthralgia
    • Jessica A B van Nies,
    • Elisabeth Brouwer,
    • Diederik P C de Rooy,
    • Floris A van Gaalen,
    • Tom W J Huizinga,
    • Marcel D Posthumus,
    • Annette H M van der Helm-van Mil
    Ann Rheum Dis Published Online First: 6 September 2012 doi:10.1136/annrheumdis-2012-201995
    Clinical and epidemiological research: Extended report: Improved early identification of arthritis: evaluating the efficacy of Early Arthritis Recognition Clinics
    • Jessica A B van Nies,
    • Elisabeth Brouwer,
    • Floris A van Gaalen,
    • Cornelia F Allaart,
    • Tom W J Huizinga,
    • Marcel D Posthumus,
    • Annette H M van der Helm-van Mil
    Ann Rheum Dis Published Online First: 5 September 2012 doi:10.1136/annrheumdis-2012-202289
    Clinical and epidemiological research: Extended report: The incidence of rheumatoid arthritis in the UK: comparisons using the 2010 ACR/EULAR classification criteria and the 1987 ACR classification criteria. Results from the Norfolk Arthritis Register
    • Jennifer H Humphreys,
    • Suzanne M M Verstappen,
    • Kimme L Hyrich,
    • Jacqueline R Chipping,
    • Tarnya Marshall,
    • Deborah P M Symmons
    Ann Rheum Dis Published Online First: 3 September 2012 doi:10.1136/annrheumdis-2012-201960
    Open Access
    Clinical and epidemiological research: Extended report: Clinical associations of the metabolic syndrome in systemic lupus erythematosus: data from an international inception cohort
    • Ben Parker,
    • Murray B Urowitz,
    • Dafna D Gladman,
    • Mark Lunt,
    • Sang-Cheol Bae,
    • Jorge Sanchez-Guerrero,
    • Juanita Romero-Diaz,
    • Caroline Gordon,
    • Daniel J Wallace,
    • Ann E Clarke,
    • Sasha Bernatsky,
    • Ellen M Ginzler,
    • David A Isenberg,
    • Anisur Rahman,
    • Joan T Merrill,