Article Text
Correspondence response
Amino-bisphosphonates, γδT cells, and their roles in Rheumatoid Arthritis
Statistics from Altmetric.com
We thank Dr Rossini and colleagues1 for their interesting comments on our manuscript.2
Aminobisphosphonates (N-BPs), the analogue of isopentenyl pyrophosphate, promote the activation and proliferation of peripheral γδ T cells, specifically Vγ9/Vδ2 T cells,3 which are the cells we showed that play an important role in the pathogenesis of rheumatoid arthritis (RA).2 We fully agree that γδ T cells are one of the major factors that may contribute to N-BPs-related acute phase response …
Footnotes
Contributors All authors equally contributed to the writing of the manuscript. HC and XZ are the corresponding authors.
Competing interests None declared.
Provenance and peer review Commissioned; internally peer reviewed.
Linked Articles
- Correspondence