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Utility of PET/CT in the diagnosis of inflammatory rheumatic diseases: a systematic review and meta-analysis
  1. Lucie Descamps1,
  2. Louis Olagne2,
  3. Charles Merlin3,
  4. Florent Cachin3,
  5. Martin Soubrier1,
  6. Sylvain Mathieu1
  1. 1Rheumatology Department, Gabriel Montpied Teaching Hospital, Clermont University, Clermont-Ferrand, France
  2. 2Internal Medicine Department, Gabriel Montpied Teaching Hospital, Clermont University, Clermont-Ferrand, France
  3. 3Nuclear Medicine, Jean Perrin Comprehensive Cancer Center, Clermont-Ferrand, France
  1. Correspondence to Sylvain Mathieu, Rheumatology Department, Gabriel Montpied Teaching Hospital, Clermont-Ferrand 63003, France; smathieu{at}chu-clermontferrand.fr

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In an article published in the Annals of the Rheumatic Diseases, Schönau et al suggested that positron emitted tomography (PET)/CT is useful in determining the cause of unexplained fever/inflammation.1 In this letter, we wish to add further data to support the conclusions of this article. More and more, PET/CT is used to determine the cause of fever, systemic inflammation or atypical or resistant rheumatic disease. However, the utility of PET/CT in these diagnoses is not clear. Thus, we performed a meta-analysis to investigate the utility of PET/CT in the diagnosis of inflammatory rheumatic diseases.

We searched MEDLINE to identify all reports of interest published prior to June 2016 using the search terms: ‘(PET scan OR …

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