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Challenging judgement of a low-positive ACPA test in the context of individuals at risk of RA
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  1. Aase Haj Hensvold,
  2. Anca I Catrina
  1. Rheumatology Unit, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden
  1. Correspondence to Dr Aase Haj Hensvold, Rheumatology Unit, Karolinska University Hospital and Karolinska Institutet, CMM L8:04, Stockholm 171 76, Sweden; aase.hensvold{at}sll.se

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We thank Bossuyt1 for his letter and the comments related to our previous published study.2 We agree that the calculated test likelihood ratios for low-positive anticitrullinated protein antibody (ACPA) reflect the relative uncommonness of low-titre ACPA in …

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