A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus

Ana Márquez; Laura Vidal-Bralo; Luis Rodríguez-Rodríguez; Miguel A González-Gay; Alejandro Balsa; Isidoro González-Álvaro; Patricia Carreira; Norberto Ortego-Centeno; María M Ayala-Gutiérrez; Francisco José García-Hernández; M Francisca González-Escribano; José Mario Sabio; Carles Tolosa; Ana Suárez; Antonio González; Leonid Padyukov; Jane Worthington; Timothy Vyse; Marta E Alarcón-Riquelme; Javier Martín

doi:10.1136/annrheumdis-2016-209436

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Basic and translational research

Extended report

A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus

Authors

Ana Márquez Instituto de Parasitología y Biomedicina “López-Neyra”, CSIC, PTS Granada, Granada, Spain Systemic Autoimmune Diseases Unit, Hospital Clínico San Cecilio, Granada, Spain PubMed articles Google scholar articles
Laura Vidal-Bralo Laboratorio de Investigación 10 and Rheumatology Unit, Instituto de Investigación Sanitaria—Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain PubMed articles Google scholar articles
Luis Rodríguez-Rodríguez Rheumatology Department and Heath Research Institute (IdISSC), Hospital Clinico San Carlos, Madrid, Spain PubMed articles Google scholar articles
Miguel A González-Gay Department of Rheumatology, Hospital Universitario Marqués de Valdecilla, IDIVAL, Santander, Spain PubMed articles Google scholar articles
Alejandro Balsa Department of Rheumatology and Institute for Health Research (IdiPAZ), University Hospital La Paz, Madrid, Spain PubMed articles Google scholar articles
Isidoro González-Álvaro Rheumatology Service and Health Research Institute (IP), Hospital Universitario de La Princesa, Madrid, Spain PubMed articles Google scholar articles
Patricia Carreira Rheumatology Department, Hospital 12 de Octubre, Madrid, Spain PubMed articles Google scholar articles
Norberto Ortego-Centeno Systemic Autoimmune Diseases Unit, Hospital Clínico San Cecilio, Granada, Spain PubMed articles Google scholar articles
María M Ayala-Gutiérrez Department of Internal Medicine, Hospital Carlos Haya, Málaga, Spain PubMed articles Google scholar articles
Francisco José García-Hernández Department of Internal Medicine, Hospital Universitario Virgen del Rocío, Sevilla, Spain PubMed articles Google scholar articles
M Francisca González-Escribano Department of Immunology, Hospital Universitario Virgen del Rocío (IBiS, CSIC, US), Sevilla, Spain PubMed articles Google scholar articles
José Mario Sabio Department of Internal Medicine, Hospital Virgen de las Nieves, Granada, Spain PubMed articles Google scholar articles
Carles Tolosa Department of Internal Medicine, Hospital Parc Taulí, Sabadell, Spain PubMed articles Google scholar articles
Ana Suárez Department of Functional Biology, Immunology Area, Faculty of Medicine, University of Oviedo, Oviedo, Spain PubMed articles Google scholar articles
Antonio González Laboratorio de Investigación 10 and Rheumatology Unit, Instituto de Investigación Sanitaria—Hospital Clinico Universitario de Santiago, Santiago de Compostela, Spain PubMed articles Google scholar articles
Leonid Padyukov Rheumatology Unit, Department of Medicine, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Jane Worthington Arthritis Research UK Centre for Genetics and Genomics, Centre for Musculoskeletal Research, Institute of Inflammation and Repair, Manchester Academic Health Science Centre, The University of Manchester, Manchester, UK PubMed articles Google scholar articles
Timothy Vyse Division of Genetics and Molecular Medicine, King's College London, London, UK Division of Immunology, Infection and Inflammatory Disease, King's College London, London, UK PubMed articles Google scholar articles
Marta E Alarcón-Riquelme Centro de Genómica e Investigación Oncológica (GENYO), Pfizer-Universidad de Granada-Junta de Andalucía, Granada, Spain Institute for Environmental Medicine, Karolinska Institutet, Stockholm, Sweden PubMed articles Google scholar articles
Javier Martín Instituto de Parasitología y Biomedicina “López-Neyra”, CSIC, PTS Granada, Granada, Spain PubMed articles Google scholar articles

Correspondence to Dr Ana Márquez, Instituto de Parasitología y Biomedicina López-Neyra, Consejo Superior de Investigaciones Científicas, Parque Tecnológico Ciencias de la Salud, Avenida del Conocimiento s/n Armilla, Granada 18016, Spain; anamaort{at}ipb.csic.es

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Citation

Márquez A, Vidal-Bralo L, Rodríguez-Rodríguez L, et al

A combined large-scale meta-analysis identifies COG6 as a novel shared risk locus for rheumatoid arthritis and systemic lupus erythematosus

Annals of the Rheumatic Diseases 2017;76:286-294.

Publication history

Received February 24, 2016
Revised April 14, 2016
Accepted April 29, 2016
First published May 18, 2016.

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November 02, 2019

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