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  • Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice

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Basic and translational research
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Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice

Authors

  • Min-jun Huang Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Liang Wang Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Da-di Jin Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Zhong-min Zhang Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Tian-yu Chen Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Chun-hong Jia Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Yan Wang The Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu, PR China PubMed articlesGoogle scholar articles
  • Xiao-chen Zhen Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Bin Huang Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Bo Yan Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Yu-hui Chen Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Sheng-fa Li Department of Orthopedics, The Third Affiliated Hospital of Southern Medical University, Guangzhou, Guangdong, PR China Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Jin-cheng Yang Department of Orthopedics, Liu Hua Qiao Hospital, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  • Yi-fan Dai The Center of Metabolic Disease Research, Nanjing Medical University, Nanjing, Jiangsu, PR China PubMed articlesGoogle scholar articles
  • Xiao-chun Bai Academy of Orthopedics, Guangdong Province, Guangzhou, Guangdong, PR China Department of Cell Biology, School of Basic Medical Science, Southern Medical University, Guangzhou, Guangdong, PR China PubMed articlesGoogle scholar articles
  1. Correspondence to Dr Xiao-chun Bai, Department of Cell Biology, School of Basic Medical Science, Southern Medical University, 1838 North Guangzhou Avenue, Guangzhou 510515, China; baixc15{at}smu.edu.cn
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Citation

Huang M, Wang L, Jin D, et al
Enhancement of the synthesis of n-3 PUFAs in fat-1 transgenic mice inhibits mTORC1 signalling and delays surgically induced osteoarthritis in comparison with wild-type mice
Annals of the Rheumatic Diseases 2014;73:1719-1727.

Publication history

  • Received January 4, 2013
  • Revised June 27, 2013
  • Accepted June 29, 2013
  • First published July 12, 2013.
Online issue publication 
October 25, 2017

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