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Neuropeptides activate TRPV1 in rheumatoid arthritis fibroblast-like synoviocytes and foster IL-6 and IL-8 production

https://doi.org/10.1136/annrheumdis-2012-202846

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    Footnotes

    • *RT and ER contributed equally.

    • Contributors All authors were involved in drafting the article or revising it critically for important intellectual content and all authors approved the final version to be published. RT, ER, MM, MM-C, SG: Study conception and design; RT, ER, MM, FP, FN, MM-C, SG: Acquisition of data; RT, ER, MM, SG: Analysis and interpretation of data.

    • Funding This study has been supported by grants from the University of Florence (Progetti di Ricerca di Ateneo, ex 60% to M. Matucci-Cerinic).

    • Competing interests None.

    • Patient consent Obtained. All subjects gave written informed consent.

    • Ethics approval The study was approved by the Institutional Review Board.

    • Provenance and peer review Not commissioned; externally peer reviewed.